New data from a US institution suggests that the prevalence of Cushing syndrome in the United States may be higher than previously thought. Researchers at the University of Wisconsin estimate an incidence of at least 7.2 cases per million patient-years in Wisconsin, with adrenal Cushing syndrome more common than pituitary ACTH-secreting tumors. Milder cases of hypercortisolism may be going undiagnosed, leading to long-term damaging effects. While Wisconsin may have a lower threshold for diagnosing milder cases, detecting even mild hypercortisolism is important for preventing adverse health outcomes. The study’s findings may not be representative of Cushing syndrome prevalence nationwide.
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Is Cushing Syndrome More Common in the US Than We Think?
