Foam technology revolutionizes gene therapy, boosting efficiency and safety

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The study published in Nature Communications explores the benefits of using liquid foam as a drug delivery system, specifically for gene therapy. The researchers investigated the safety, practicality, and cost-effectiveness of foam-based vectors compared to traditional liquid-based gene delivery agents. The study found that a liquid foam made of FDA-approved methylcellulose and xanthan gum showed significant improvements in transfection efficiency in nonviral gene delivery to murine models. Foam-based vectors prevent leakage of DNA cargo, reduce treatment cost, and increase safety by shielding the vector from the immune system. The study suggests that foam-based drug delivery systems have the potential to revolutionize gene therapy, making it more accessible and effective for a wide range of diseases.

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