Research suggests that reports of memory issues in older adults are linked to higher levels of tau neurofibrillary tangles in the brain, even without overt clinical symptoms. This highlights the importance of understanding early signs of Alzheimer’s disease, especially with new drugs available. Subjective cognitive decline, reported by both individuals and their partners, may be an early indicator of AD. The study involved 675 cognitively unimpaired older adults, with findings showing that tau levels were associated with self- and partner-reported cognitive decline. Partner reporting may be valuable for early detection, especially in individuals with elevated AD biomarkers. Future studies should include more diverse participants.
Source link
Early Memory Problems Linked to Increased Tau
