Studies have shown that antidepressant discontinuation symptoms are less common than previously believed, with only 15% of patients experiencing true symptoms. Severe symptoms occurred in about 2% of patients. These findings aim to calm the debate around antidepressant discontinuation symptoms and highlight the importance of being aware of the placebo effect. The study involved a meta-analysis of 44 controlled trials and 35 observational studies, including 21,002 patients. Different medications were associated with different rates and severity of discontinuation symptoms. Ultimately, patients and doctors should be aware of the potential for symptoms and carefully monitor those who discontinue antidepressant therapy.
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Antidepressant Withdrawal Symptoms Much Lower Than Thought
