A study conducted in Australia found that using 5-mm margins to manage small melanoma in situ (MIS) lesions on low-risk body sites resulted in a low local recurrence rate of 0.9%. This approach potentially reduces treatment-related morbidity and costs without compromising patient outcomes. The retrospective analysis included 351 MIS lesions from 292 patients with a mean follow-up of 7 years. Only three lesions (0.9%) had local recurrence, which was successfully reexcised, and no regional or metastatic spread occurred. The study suggests that a 5-mm excisional margin may be effective for treating select MIS lesions on low-risk body sites. Further research is recommended to confirm these findings.
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5-mm Margin Excision Evaluated in Small Melanoma In Situ
