Children in urban areas with asthma and overweight or obesity have significant metabolic changes compared to other urban children with asthma. Obesity-related asthma is a growing issue in inner cities, leading to greater asthma symptoms, healthcare use, and poor response to standard treatments. Metabolomic profiling may help link genetics and environmental factors, allowing for more targeted treatments. The study analyzed metabolites in children with asthma and overweight or obesity, showing elevated levels of certain compounds and metabolic alterations affecting various pathways. Further research is needed to understand the underlying mechanisms and develop more precise therapeutics for this specific asthma phenotype.
Source link
Urban children with obesity-related asthma exhibit significant metabolic changes
