A recent study led by McLean Hospital researchers sheds new light on the molecular mechanisms underlying schizophrenia by analyzing genetic and cellular data from postmortem brain tissue. The research identified specific neuronal populations affected by genetic risk factors for schizophrenia, particularly implicating excitatory neurons and neurodevelopmental pathways. This study provides insights that could lead to personalized treatments for schizophrenia in the future, improving outcomes for the estimated 24 million people worldwide affected by this disorder. The researchers are now expanding their investigation to other brain regions and exploring the molecular impact of other psychiatric diseases to further understand the complexity of schizophrenia.
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Study sheds new light on the intricate molecular mechanisms underlying schizophrenia
