Researchers at the University of Cologne found that reducing glycogen levels in fruit flies improves short-term memory related to food intake. The study focused on how the neurotransmitter octopamine influences the formation of food-related memories based on internal energy reserves in the body. High glycogen levels led to stable memories of food intake, even during fasting, which resulted in increased food intake. This mechanism could explain overeating and contribute to the development of obesity. The findings suggest that erasing long-lasting memories of food rewards may be important for weight loss. The study could provide insights into human eating behavior and weight management.
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