A breakthrough study presented at the 61st ERA Congress has identified anti-nephrin autoantibodies as a reliable biomarker for tracking kidney diseases associated with nephrotic syndrome. The study, also published in the New England Journal of Medicine, used a hybrid technique to detect these autoantibodies, revealing their correlation with disease activity. This discovery opens new avenues for personalized treatment approaches for conditions like minimal change disease and focal segmental glomerulosclerosis. The researchers also established a mouse model that mimics these kidney diseases, providing insights into underlying mechanisms and paving the way for precision medicine in the diagnosis and monitoring of nephrotic syndrome.
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New technique detects novel biomarkers for kidney diseases with nephrotic syndrome
