A study published in Environment International explored the impact of PFAS compounds on sperm DNA methylation and gene expression in offspring’s metabolic organs. Male fertility is decreasing globally due to exposure to EDCs like PFAS, which affect hormone levels. PFAS presence in human blood and semen raises concerns about male fertility. Exposure to PFOS alters testosterone levels and sperm development. PFAS exposure in mice led to changes in sperm methylation and gene expression in offspring’s livers and fat cells. The study uncovered specific molecular processes affected by PFAS exposure, highlighting potential risks to male fertility and offspring health.
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Mouse study finds PFAS exposure in fathers disrupts offspring’s gene expression
