A systematic review and meta-analysis published in The Lancet Psychiatry found that clinical trials of psychological interventions for depression often do not assess suicidality, despite the known association between depression and suicide risk. Most trials did not include assessments for suicide, with only a small number reporting on suicidal thoughts and behaviors as adverse events. However, psychological interventions, such as cognitive behavioral therapy, were found to significantly reduce suicidal ideation and suicide risk immediately after the intervention. The study authors emphasized the need for improved monitoring and reporting of suicidal thoughts and behaviors in psychotherapy trials, even when individuals at risk of suicide are excluded.
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Trials of Psychological Interventions for Depression Rarely Assess Suicidality
