Study highlights impact of aldehydes on DNA damage and aging

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A study by researchers at Nagoya University in Japan reveals that aldehydes are metabolic byproducts linked to premature aging, with implications for aging diseases and potential ways to combat aging by controlling exposure to aldehyde-inducing substances like alcohol, pollution, and smoke. Aldehydes damage DNA and proteins by forming DNA-protein crosslinks, leading to cellular processes malfunctioning and premature aging. The study suggests a connection between aldehyde accumulation and premature aging diseases, shedding light on potential therapeutic interventions. Furthermore, the findings suggest aldehyde-induced DNA damage may also impact healthy individuals’ aging processes, emphasizing the relationship between environmental factors and cellular aging.

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