Preoperative antibiotic therapy decreased microbiologic culture yield

Preoperative antibiotic therapy in patients with native joint septic arthritis led to a significant decrease in operative culture yield, according to a recent study. Researchers found that patients who received preoperative antibiotics had a lower microbiologic yield in operative cultures compared to those who did not receive antibiotics. Additional doses and earlier initiation of antibiotics also contributed to decreased culture positivity. The study emphasized the importance of a thoughtful approach to antibiotic therapy and surgical management in native joint septic arthritis, recommending diagnostic arthrocentesis before antibiotic initiation to improve culture yield and guide antibiotic therapy decisions.

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