The Lancet Commission on prostate cancer predicts a doubling of cases worldwide by 2040, with the highest increases in low- and middle-income countries. Annual deaths are expected to rise by 85%, primarily in LMICs. Early detection programs are crucial, with MRI scans recommended for high-risk men in high-income countries. In LMICs, outreach programs like ‘The Man Van’ can aid in detection. Public awareness of advanced prostate cancer and available treatments, especially in LMICs, needs improvement. Building capacity for diagnosis and treatment in LMICs is necessary. More research on ethnic disparities in care and survival is needed.
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