A new study found that the level of physical activity needed to prevent obesity varies depending on an individual’s genetic risk. Researchers used genetic data from the All of Us Research Program to measure the genetic risk of higher body mass index (BMI) as a polygenic risk score (PRS) and physical activity as daily step counts. The study showed that individuals with a higher genetic risk for obesity would need to take more steps daily to reduce their risk compared to those with lower genetic risk. The findings suggest that personalized activity recommendations based on genetic background could be more effective in preventing obesity.
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