Researchers at the University of Michigan have created a detailed atlas of the human ovary, identifying the different compartments and processes involved in follicle maturation and egg production. This new insight could lead to the development of artificial ovaries using stored tissues for patients who have undergone toxic medical treatments. By understanding gene expression at a single-cell level, the researchers hope to create functional follicles that can be transplanted back into the body, providing longer fertility windows and facilitating hormone production. This work is part of the Human Cell Atlas project and aims to understand the female reproductive system better.
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First atlas of the human ovary with cell-level resolution is a step toward artificial ovary
