Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets
Artistic rendering of a chimeric antigen receptor (CAR) (blue) on a T cell attaching to a targeted cancer protein (red) on another cell. Credit: St. Jude Children’s Research Hospital Targeting anti-cancer therapy to affect cancer cells but not healthy cells is challenging. For chimeric antigen receptor (CAR) T–cell immunotherapy, where a patient’s own immune cells…