FogPharma, an oncology startup based in Cambridge, Mass., recently closed a $145 million Series E round of financing. The company is developing cancer treatments using unique peptides called helicons that could potentially improve cell penetration. CEO Mathai Mammen believes that many drugs released by pharma and biotech companies are only incrementally better than existing treatments,…
Yemisi Bokinni, a freelance journalist in London, reports on the economic struggles facing Nigeria due to the departure of major drug companies. This has led to a 1100% increase in antibiotic costs and other healthcare prices in the country. The escalating drug prices reflect a larger issue with Nigeria’s economy, with inflation reaching a 27-year…
Chimeric antigen receptor (CAR)-T cell therapy is a promising treatment for cancer, but it is not always effective in neuroblastoma, a deadly childhood cancer. Researchers have found that combining CAR-T cells with an ALK inhibitor drug can enhance the therapy’s effectiveness by increasing the number of targets for the CAR-T cells to attack. In preclinical…
Health providers and addiction experts are concerned about the unstable funding structure of California’s CA Bridge initiative, which aims to place patients with substance use disorder into long-term treatment after they leave the emergency room. The program, which relies on one-time funding, has led to employees leaving critical positions. Despite the program’s success in prescribing…
Motivating a child to exercise can be challenging if they aren’t interested, but there are ways to inspire them. Dr. Blaise A. Nemeth suggests exercising with your child in a fun way, talking about the benefits of physical activity, and finding creative ways to get them moving without them realizing. Understanding why your child may…
A 20-year study tracked biomarker changes in adults progressing from normal cognition to sporadic Alzheimer’s disease (AD), using cerebral spinal fluid (CSF) analysis, cognitive assessments, and brain imaging. Changes in levels of Aβ42, p-tau181, and NfL were observed years before clinical symptoms appeared, with accelerated changes followed by a slowing of progression up to diagnosis….
Eating disorders affect millions of people in the United States, with binge eating being one of the most common. Overeating and binge eating are different, with the latter involving loss of control and distress. Binge eating is characterized by frequent episodes of consuming large amounts of food in a short period, often as a coping…
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Orbis Medicines, a biotech company based in Copenhagen, aims to develop peptide-based drugs that can be dosed orally, unlike traditional biologic drugs that require injection or infusion. Backed by €26 million in seed financing, Orbis’s technology platform enables the design of macrocycles with desired properties such as oral bioavailability and cellular permeability. These compounds have…
The ‘I Am Number 17’ campaign in Ireland aims to bring awareness to rare diseases, with statistics showing that 1 in 17 people will be affected by one in their lifetime. An exhibition featuring 17 individuals living with rare diseases has been launched in Dublin, showcasing their resilience and stories. The campaign, funded by Takeda…
