Delgocitinib cream outperforms alitretinoin capsule in treating severe chronic hand eczema

Delgocitinib cream, an investigational topical pan-Janus kinase inhibitor, has demonstrated superiority to alitretinoin capsules in the treatment of severe chronic hand eczema. In a phase 3 study, delgocitinib cream achieved better outcomes in reducing hand eczema severity, improving quality of life, and experiencing fewer adverse events compared to alitretinoin capsules. Currently, delgocitinib cream is not…

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Surprise medical billing ban raises prices elsewhere

The federal law banning surprise billing is protecting patients from huge medical bills but is raising costs elsewhere. New progress report shows that in over 80% of payment disputes, insurance companies were ordered to pay more to an out-of-network provider than to a contracted one. The arbitration process is taking up more time than expected,…

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John Miell | The BMJ

John Miell, born in Windsor, studied endocrinology at major international centers. He also served in the Royal Navy and spent a year in Antarctica after the Falklands War. After returning to the UK, he was awarded his doctorate of medicine. Source link

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Hitchhiking cancer vaccine makes progress in the clinic

Darrell Irvine developed “amphiphile” vaccines that hitch a ride on albumin molecules to the lymph nodes, where they teach the immune system to fight cancer. Elicio Therapeutics, the MIT spinout, is testing the vaccines in clinical trials and has produced promising early results in treating pancreatic cancer. Therapeutic cancer vaccines have not lived up to…

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Study suggests patients with severe long COVID present with variable symptoms, do not cluster in relation to organs affected or immunological states

A new preprint on medRxiv summarizes a study called “Restrained memory CD8+ T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID” which discusses associations found in long COVID. The study points to evidence indicating a link between persistent viral RNA and elevated antibody responses. The study focused on…

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Age-Friendly Health Care: A New Approach

America’s senior population has grown by 34.2% in the last 10 years, with about 54 million Americans aged 65-plus. Many seniors take multiple medications, see multiple doctors annually, and have at least one chronic health condition. A study found that one in five seniors experienced age discrimination from their doctors or during hospital visits. The…

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Nurse Workforce Bounces Back After Pandemic Fears

A new study indicated that nurse employment in the US has grown despite fears of a potential shortage due tothe COVID-19 pandemic. The number of registered nurses (RNs) employed increased by 6% from 2019 to 2023 and is projected to reach 4.56 million by 2035. However, concerns remain about nurse burnout and high patient-to-nurse ratios….

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COVID-19 Vaccination Or Booster During Pregnancy Protects Infants For 6 Months: Study

A study published in the journal Pediatrics found that pregnant women who receive an mRNA-based COVID-19 vaccination or booster during pregnancy can protect their infants against symptomatic COVID-19 infection for at least six months after birth. This underscores the importance of getting vaccinated during pregnancy to ensure infants are born with strong protection until they…

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