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Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 Inulin, a type of fiber found in certain plant-based foods and fiber supplements, causes inflammation in the gut and exacerbates inflammatory bowel disease in a preclinical model, according to a new study by Weill Cornell…
LONG BEACH, California — An experimental new gene therapy has specialists questioning whether heart vessel growth to restore blood flow could actually be possible in refractory angina after bypass surgery. “These patients by definition have exhausted all medical and surgical options in terms of revascularization,” reported lead study investigator Kenta Nakamura, MD, an interventional cardiologist…
Antidepressant medication use is not associated with long-term cognitive decline, brain atrophy, or dementia risk, according to results from a prospective cohort study published in Alzheimer’s and Dementia. Although antidepressants are used widely and have become more frequently used among older adults, the long-term effects of antidepressant use on cognition and dementia remain uncertain. To…
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Non-enzymatic production of diindoles. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-46559-3 Researchers at the University of Toronto have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues. This can be achieved by binding the compounds to an important, but poorly understood, nuclear receptor. The gut…
TOPLINE: iGlarLixi, a fixed-ratio combination of insulin glargine and the glucagon-like peptide-1 receptor agonist (GLP-1 RA) lixisenatide, improves glycemic control, with a low rate of hypoglycemia, in adults with inadequately controlled type 2 diabetes (T2D). METHODOLOGY: The 2022 Consensus Statement from the American Diabetes Association/European Association for the Study of Diabetes suggests that a fixed-ratio…
Hospitals’ operating margins and patient volumes dropped slightly in March, according to a new report from Kaufman Hall. Hospitals’ single-month operating margin index closed out March at 3.4% — a small dip from February’s 3.6%. It’s also worth noting that March ended with a year-to-date operating margin index of 3.9% — which is still significantly…
Therapist burnout negatively affected the delivery of trauma-focused psychotherapies (TFPs) to patients with posttraumatic stress disorder (PTSD), according to study results published in JAMA Network Open. Clinicians who experience burnout have previously reported that their symptoms affect the quality of care they deliver, their communication with patients, and the likelihood of making a medical error….
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