Alex Lugovskoy, CEO of Diagonal Therapeutics, aims to develop antibodies that activate targets, rather than just inhibit cellular functions. Using computational and experimental techniques, the startup focuses on binding combinations to yield desired effects. Diagonal’s platform, developed over two years, includes a lead program for a rare bleeding disorder without FDA-approved therapies. Their technology, which…
The SMART trial compared self-expanding and balloon-expandable valves in patients with small aortic annuli undergoing TAVR. The study showed that self-expanding valves had better hemodynamic results at 1 year, with no difference in clinical outcomes. The trial, which enrolled primarily women, found that the self-expanding valve had lower rates of bioprosthetic valve dysfunction compared to…
Cancer cases among younger people have been increasing, with new evidence showing that younger generations are aging faster at the cellular level. A study of nearly 150,000 people in the UK found that those born after 1965 had a biological age that exceeded their chronological age, leading to a 17% increased risk of developing solid…
Cognitive decline and dementia impact over 55 million people globally, with this number expected to rise as the population ages. While genetic factors play a role, modifiable lifestyle habits like smoking, obesity, and lack of exercise are linked to a higher risk of dementia. Research suggests that following a traditional Japanese diet, characterized by foods…
A study published in Nutrients investigated the link between ultra-processed food intake and glaucoma among Spanish university graduates. Glaucoma, a leading cause of blindness worldwide, is influenced by factors like age, race, and genetics, but nutrition plays a role. The study followed 19,255 participants for 13 years and found those with high ultra-processed food intake…
Leslie Crowder received a pink silk scarf with elephants from her mother days before starting chemotherapy for breast cancer. Her mother, sisters, and others wore a matching scarf every Friday to show support during her treatment. Ranak Trivedi, an expert on caregiving and long-distance caregiving, provided tips on how to help loved ones facing cancer…
A pivotal trial showed that semaglutide, a GLP-1 receptor agonist, improved symptoms in patients with heart failure, obesity, and diabetes, similar to those without diabetes. The trial, conducted in patients with heart failure with preserved ejection fraction (HFpEF), obesity, and type 2 diabetes, demonstrated significant weight loss and improvement in quality of life compared to…
A review has found that patients taking semaglutide may experience a higher rate of altered skin sensations and alopecia. These side effects should be considered when prescribing this medication. Additionally, the use of cookies for analytics, advertising, and site improvement is acknowledged and continued use of the site implies agreement to their use. Further information…
Heali, a food as medicine platform, has partnered with Medicaid in California to provide personalized nutrition plans for over 200 chronic conditions through its AI-driven app. The company aims to expand its partnerships with more Medicaid programs in the future. Heali has launched its Medical Nutrition Therapy tool, offering evidence-based dietary recommendations for various conditions….
The Royal Victoria Eye and Ear Hospital is a specialist hospital for eye, ear, nose, throat, and head and neck disorders. It is a University Teaching Hospital with a history dating back to 1814. They are currently seeking candidates for medical positions, specifically a Senior House Officer in Ophthalmology from July 2024 to January 2025….
