RESPONSE

Guedes et al.1 measured exosomal and plasma biomarkers in veterans with a history of mild traumatic brain injury (mTBI) and tested their relationships with chronic symptoms. Neurofilament light (NfL) chain, tumor necrosis factor…

We thank Dr. Sioka et al. for their positive comments about our article1 showing a high risk of major adverse cardiovascular events after acute ischemic stroke. They also summarized the results of their study on myocardial perfusion…

In their large population-based study, Sposato et al.1 reported that ischemic stroke was independently associated with a higher risk of a subsequent major adverse cardiovascular event, such as myocardial infarction, congestive heart…

Credit: © Institut Pasteur Describing the genetic diversity of human populations is essential to improve our understanding of human diseases and their geographical distribution. However, the vast majority of genetic studies have…

We thank Dr. Kawada for his comments and inquiry on our article.1 Our report of plasma and exosomal axonal, inflammatory, and vascular biomarkers is part of a discovery project studying candidate biomarkers of remote mild TBI (mTBI)…

MENLO PARK, Calif.--(BUSINESS WIRE)--Synthekine Inc., an engineered cytokine therapeutics company, today announced preclinical data presented at the American Association of Cancer Research Annual Meeting 2021 demonstrating its alpha/beta…

Dana-Farber researchers find patients whose tumors have low aneuploidy levels often have better outcomes following treatment with immune checkpoint inhibitors Credit: Dana-Farber Cancer Institute Patients with non-small cell lung…

(MedPage Today) -- Substituting a targeted agent for a chemotherapy drug improved tolerance of an established therapy for high-risk pediatric Hodgkin lymphoma and allowed a third of patients to avoid nodal irradiation, a prospective…

Eur Arch Psychiatry Clin Neurosci. 2021 Apr 5. doi: 10.1007/s00406-021-01257-9. Online ahead of print.ABSTRACTTo investigate pharmacokinetic correlates of clinical response in patients treated with once-monthly paliperidone palmitate…

We thank Dr. Blumenfeld for his comments on our article.1 In our manuscript, we acknowledged that—in this cross-sectional analysis—we cannot determine the causal sequence that links opioid use to migraine features, such as…

Despite guidelines directing against the use of opioids in migraine management, this analysis by Lipton et al.1 reveals that more than 36% of patients surveyed have opioids available to them. These opioid users were more likely to have…

We thank Dr. Gupta for his comments on our article.1 We agree that patterns of opioid use vary by region of the world and acknowledge that opioid treatment of migraine may be particularly problematic in the United States.2 We also agree…

I read the article by Lipton et al.1 Epidemic opioid use disorder, most apparent in North America and parts of Europe, is associated with widespread access to prescription opioid analgesics.2 Over the 4 decades that I have worked in…

Opioids are not the recommended treatment for migraine. In this study by Lipton et al.,1 which compared people with migraine who were opioid users vs nonusers, opioid users were less likely to have a self-reported physician-diagnosed…

In a study published on the bioRxiv* preprint server, researchers report the effect of neutralizing antibodies from recovered patients or mRNA vaccinated individuals on neutralizing this variant. Source link

We thank Dr. Minen for her comment on our article,1 and we agree that additional training and education in headache management is needed for ED/UC physicians and pain specialists. Furthermore, we are encouraged by the community-led…

BELLEVUE, Wash.--(BUSINESS WIRE)--Daiya Healthcare Expands Behavioral Health Program Source link

Ann Pharmacother. 2021 Apr 3:10600280211007213. doi: 10.1177/10600280211007213. Online ahead of print.ABSTRACTBACKGROUND: No clear association between standard vasopressin doses and body mass index exists, despite potential…

A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.…

Study identifies a novel mechanism in which the lateral habenula regulates the cardiovascular system in response to stress. Source link