Resistance

Related Articles Predicting antimicrobial resistance using conserved genes. PLoS Comput Biol. 2020 10;16(10):e1008319 Authors: Nguyen M, Olson R, Shukla M, VanOeffelen M, Davis JJ Abstract…

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Related Articles The Metabolic Role of GRK2 in Insulin Resistance and Associated Conditions. Cells. 2021 Jan 15;10(1): Authors: Sorriento D, Rusciano MR, Visco V, Fiordelisi A, Cerasuolo FA, Poggio P,…

Credit: Jan Zrimec/Chalmers University of Technology Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected. Now, computational research at Chalmers University of Technology, Sweden, shows…

New high-resolution structures of the bacterial ribosome determined by researchers at the University of Illinois Chicago show that a single water molecule may be the cause -; and possible solution -; of antibiotic resistance. Source…

New images first to show water molecule present in drug-resistant bacteria models Credit: Jenny Fontaine/UIC New high-resolution structures of the bacterial ribosome determined by researchers at the University of Illinois Chicago…

A decrease in activation of the LEF1 gene may be the reason why many patients with bipolar disorder do not respond to lithium, considered the 'gold standard' treatment, new research suggests. Medscape Medical News Source link

Insulin resistance is associated with poor functional outcome after acute ischemic stroke in non-diabetic patients Source link

Tumor-infiltrating mast cells are connected to immune checkpoint inhibitor resistance in melanoma Credit: The Wistar Institute PHILADELPHIA — (Jan. 12, 2021) — Scientists at The Wistar Institute have created an advanced…

An intriguing new study explores the mechanisms by which an Italian island called Giglio remained resistant to coronavirus disease 2019 (COVID-19) even after much exposure. Source link

High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Source link

Facebook Posts Big Drivers in Vaccine Resistance, Study Finds Source link

An important and still unanswered question is how new genes that cause antibiotic resistance arise. In a new study, Swedish and American researchers have shown how new genes that produce resistance can arise from completely random DNA…

AbstractWe studied five chemically distinct but related 1,3,5-triazine antifolates with regard to their effects on growth of a set of mutants in dihydrofolate reductase. The mutants comprise a combinatorially complete data set of all 16…

The mutations are already widespread in parasite populations in Africa and Asia Credit: Lauren Holden, Wellcome Collection (CC BY 4.0) In the ongoing arms race between humans and the parasite that causes malaria, Taane Clark and…

In the ongoing arms race between humans and the parasite that causes malaria, Taane Clark and colleagues at the London School of Hygiene and Tropical Medicine (LSHTM) report that new mutations that enhance resistance to a drug used to…

Related Articles Resistance of hepatocellular carcinoma to sorafenib can be overcome with co-delivery of PI3K/mTOR inhibitor BEZ235 and sorafenib in nanoparticles. Expert Opin Drug Deliv. 2020 04;17(4):573-587…

Credit: Ralph Panstruga & Matthew Moscou People have puzzled for years why pathogen Phytophthora infestens causes the devastating late blight disease, source of the Irish Potato famine, on potatoes, but has no effect at all on…

Related Articles A Luminescent Mg-Metal-Organic Framework for Sustained Release of 5-Fluorouracil: Appropriate Host-Guest Interaction and Satisfied Acid-Base Resistance. ACS Appl Mater Interfaces. 2020 Apr…