Immune-based therapies, like immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T cell therapy (CAR-T), have seen increased use in cancer treatment. This has led to cardiovascular adverse events, including myocarditis, pericarditis, vasculitis, thromboembolism, and accelerated atherosclerosis. ICIs impact T cell activation, leading to myocardial inflammation in ICIMy, with combination therapy increasing the risk. CAR-T…
A recent study has uncovered how SARS-CoV-2 and its variants evade the immune system, shedding light on potential therapeutic strategies for COVID-19. By focusing on the interactions between the virus and the innate immune system, researchers found that infected cells reduce important immune signals that activate natural killer cells. The study identified a viral protein,…
New research presented at the 10th European Stroke Organisation Conference reveals that high-income individuals and those with higher education levels have lower risks of post-stroke mortality. The study analyzed data from stroke patients in Gothenburg, Sweden, highlighting disparities in stroke survival based on social determinants of health (SDoH). Patients with one unfavorable SDoH factor faced…
Schizophrenia manifested in Dawn Brown’s son at a young age, leading to a difficult journey of finding effective treatment. Medication was just a small part of the treatment plan, with maintaining overall health and wellness being crucial. Engagement, empathy, and collaboration were key in helping loved ones with schizophrenia seek treatment and manage symptoms. Trial…
A study found that individuals with overweight and obesity who hit a weight loss plateau after 6 months on a healthy diet may not lose further weight by switching to a different diet. The research, conducted on participants with overweight and obesity who switched between healthy low-carb and low-fat diets, found that weight loss slowed…
Emergency Department failures are a common occurrence in the news, with a recent case of a 16-year-old girl dying from sepsis due to understaffing at University Hospital Limerick. The ED was overwhelmed with cases that night, leading to a tragic outcome. Emergency healthcare workers face challenges such as unclear workload definition, lack of control over…
The Mi’kmaq Nation used $50,000 of opioid settlement funds to build a healing lodge for sweat ceremonies to help people recover from addiction. The lodge accommodates up to 10 people at once for traditional ceremonies. The tribe received $150,000 from settlements with opioid companies, part of a larger $1.5 billion payout to tribes over 15…
Researchers found that a 12-month self-guided, low-intensity, video-based lifestyle intervention helped patients with COPD and obesity lose weight. The intervention group also showed improvements in 6-minute walk distance, dyspnea after walking, Framingham Risk score, BMI, and quality of life compared to the usual care group. However, there were no significant differences in walk distance and…
The reporter describes a strange experience purchasing raw milk, which is illegal to trade interstate, from a man named Karl in Washington. Despite the risks of illness associated with raw milk, the FDA has not enforced the ban on its transport across state lines. Raw milk enthusiasts claim it is nutritious, while public health officials…
The PRE-EMPT trial aimed to compare the clinical effectiveness of long acting progestogens with the combined oral contraceptive pill in preventing endometriosis related pain recurrence after surgery. The study included 405 women randomized to receive either a long acting progestogen or COCP. At three years, both groups showed around a 40% improvement in pain compared…
