Zepbound effective in obstructive sleep apnea trials

Eli Lilly’s obesity drug Zepbound has shown positive results in treating obstructive sleep apnea, positioning it as a potential first approved treatment for the disorder. In a year-long Phase 3 study, patients with obesity not on PAP therapy experienced a significant reduction in breathing interruptions during sleep while taking Zepbound compared to those on a…

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Vaccines targeting chronic diseases show promise in combatting age-related conditions

Researchers in a recent review in Nature Aging discuss the potential of vaccine-based therapeutics for age-related disorders. Aging is a risk factor for chronic illnesses, and vaccines provide a method to target specific antigens and generate immune responses. Vaccines that target senescent cells, cancer, Alzheimer’s disease, type 2 diabetes, vascular diseases, osteoarthritis, fibrosis, and kidney…

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When to Call a Pediatrician

New parenthood can be full of uncertainty, especially when it comes to deciding whether to call the pediatrician when your baby is sick. Key symptoms to look out for include fever, dehydration signs, persistent vomiting or diarrhea, and difficulty breathing. In some cases, a fever in a baby under 2 months old may require an…

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Guselkumab Provides Long-Term Relief From PsA Symptoms

In a post-hoc analysis of the DISCOVER-2 trial, guselkumab showed significant long-term improvement in joint symptoms, spinal pain, and skin clearance in biologic-naive patients with active psoriatic arthritis (PsA). By week 100, patients receiving guselkumab every 4 or 8 weeks experienced reductions in joint counts, improvement in skin psoriasis symptoms, and resolution of enthesitis and…

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Two Chairs Rakes In $72M For Its Hybrid Therapy Platform

Two Chairs, a San Francisco-based company, raised $72 million in a Series C funding round, bringing their total funding to $130 million. The startup offers virtual and in-person psychotherapy to adults with mental health issues. CEO Alex Katz emphasizes the importance of matching patients with the right therapist for better outcomes. Two Chairs focuses on…

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Cancer outcomes ‘at risk of going backwards’, clinicians warn

Twenty-one leading clinicians and academics have written an open letter to the Taoiseach urging the government to reverse its decision to not fund the National Cancer Strategy this year. The letter highlights the negative impact of underfunding on cancer outcomes, including delays in screenings, surgeries, and treatments. Ireland has the third-highest cancer mortality rate in…

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