This article discusses the evolving treatment trajectories for patients with incurable solid cancers, focusing on the impact of newer systemic anticancer treatments, such as immunotherapy and targeted therapy. The updated trajectories now include major temporary improvement, long term ongoing response, rapid decline due to adverse events, and the traditional trajectory. The importance of discussing patients’…
Bifidobacterium breve, a species of gut bacteria, is important for infant gut health. During childbirth, these beneficial bacteria are transferred from the mother to the baby, especially through vaginal birth. B breve plays a key role in breaking down carbohydrates, boosting the immune system, and protecting against pathogens. Breast milk, with its human milk oligosaccharides,…
Researchers have identified specific strains of bacteria in the microbiome that are linked to a positive response to combination immunotherapy in various cancers, including rare gynecological and biliary tract cancers. A study published in Nature Medicine details how understanding the microbiome at a strain-level can help predict who will benefit from immunotherapy. The research used…
Fires are becoming a worsening global crisis, with the U.S. experiencing an 8% increase in fires in 2020 compared to 2019. Survivors face long-term physical and mental health challenges, including scarring, chronic pain, PTSD, and respiratory issues. Climate change has contributed to longer and more intense wildfire seasons. The COVID-19 pandemic may have also increased…
Vector control strategies have led to a decrease in vector-borne transmission of Chagas disease in many regions, but oral ingestion of Trypanosoma cruzi through contaminated food and beverages is on the rise. This method of transmission is highly lethal, especially in pediatric and adult populations. There is a lack of awareness about oral transmission in…
People aged 65 and older are advised to get an additional COVID shot this spring by the CDC. The recommended booster dose corresponds to the latest version of Pfizer-BioNTech, Moderna, or Novavax vaccines and is meant for older adults at least four months after a previous dose. People with compromised immune systems may need extra…
A fake drugs racket was busted in Uttarakhand, where counterfeit medicines were being manufactured and sold. Authorities conducted a raid and seized a large quantity of fake drugs. The operation was a result of ongoing efforts to combat the illegal trade of counterfeit medications. Investigations are underway to identify the individuals involved in the racket…
The evolution of cloud services has changed the way organizations manage data, with multi-cloud environments becoming common for flexibility and efficiency. However, challenges in data security, especially for Protected Health Information (PHI), are increasing with cloud adoption. Safeguards are crucial to prevent misconfigurations and data breaches, especially in healthcare. Cloud Reference Architectures (CRAs) provide a…
The content is about the RCPI Faculty of Pathology’s 43rd Annual Symposium and AGM, featuring key figures such as Prof Brendan Doyle, Prof David Gonzales de Castro, Prof Ian Cree, Prof Mary Keogan, Prof Siobhan Glavey, and Dr Ennna McCann. The event included discussions and presentations on various topics related to pathology. The image shows…
A study found that false-positive findings were common in cardiovascular imaging using dual-energy computed tomography (DECT) in patients with gout. Researchers compared non-electrocardiogram (ECG)-gated DECT pulmonary angiograms in patients with and without gout, finding artifacts that could be mistaken for vascular monosodium urate (MSU) deposits. Factors such as motion, foreign bodies, and contrast medium mixing…
