Risk for blindness higher among boys with juvenile idiopathic arthritis-associated uveitis

In a study on children with juvenile idiopathic arthritis-associated uveitis, male sex, Black race, and Medicaid insurance were associated with an increased risk for blindness. The study found that disparities exist in visual outcomes and complications among these patients. Despite improvements in therapies for JIA-associated uveitis, clinicians should be aware of these disparities when evaluating…

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“Excited delirium”: can the world lose this controversial term, which is accused of covering up deaths in police custody?

Medical guidance on the term “excited delirium” is being updated, indicating a shift away from its use. The term gained attention after being used in relation to the death of George Floyd in police custody. Originally coined in the 1980s to explain unexplained deaths of black women, subsequent studies have found no medical basis for…

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Pre- and post-surgical immunotherapy improves outcomes for patients with operable lung cancer, Phase III study finds

Perioperative immunotherapy, given before and after surgery, significantly improves event-free survival in patients with early-stage non-small cell lung cancer compared to chemotherapy alone. Results from the Phase III CheckMate 77T study showed a 42% reduction in the risk of disease progression, recurrence, or death with perioperative nivolumab. Patients receiving this combination also had higher rates…

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COVID-19 linked to rise in autoimmune lung disease, study finds

A recent study in eBioMedicine found a connection between SARS-CoV-2 infection and MDA5 autoimmunity, particularly in cases of interstitial lung disease (ILD) associated with dermatomyositis (DM). The study investigated the rise in MDA5-related disease during the COVID-19 pandemic and identified an increase in MDA5+ cases in the UK in 2021. The study proposed the term…

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Testosterone/CVD Risk Debate Revived by New Meta-Analysis

A recent literature review on testosterone therapy’s impact on cardiovascular health found that while the TRAVERSE trial showed no increased risk for major cardiovascular events, other studies have yielded different results. The review, which included 11 prospective cohort studies, found that men with very low testosterone, high luteinizing hormone, or very low estradiol concentrations had…

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Better health equity needed to improve visual outcomes

Addressing social and political determinants of health is crucial for improving visual outcomes in patients, as only 20% of healthcare contributes to overall health. Factors such as socioeconomic status and physical location play a significant role in a patient’s health. Disparities exist in eye care, with conditions like diabetic retinopathy affecting Black Americans more than…

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HPV vaccine: the key to eliminating cervical cancer inequities

Trisha L Amboree, Joslyn Paguio, and Kalyani Sonawane highlight the importance of equitable access to the HPV vaccine in reducing cervical cancer inequalities. The HPV vaccine has shown effectiveness in preventing invasive cervical cancers caused by HPV strains. Falcaro and colleagues provide further evidence of the vaccine’s impact in eliminating invasive cancers and address whether…

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New method uses tau protein deposition patterns to predict Alzheimer’s severity

Researchers have developed a method to assess Alzheimer’s disease severity by analyzing patterns of tau pathology in brain scans. Using unsupervised machine learning, they identified eight patterns of tau deposition correlated with clinical outcomes. This model could help determine disease progression and guide treatment decisions. The study, published in Alzheimer’s and Dementia, aims to monitor…

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