Cancer trial discovers a potentially broader role for an established dual HER2-blocking treatment

The NCI-MATCH clinical trial published in Clinical Cancer Research found that the drug combination trastuzumab-pertuzumab, approved for HER2-positive breast cancer, shrank tumors in patients with other cancers with high levels of the HER2 gene. NCI-MATCH is one of the largest precision oncology trials globally, offering potential treatment options for patients with advanced HER2-amplified cancers. While…

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How Is Pompe Disease Diagnosed?

Pompe disease is a rare disorder that can often take years to diagnose due to its similarity to other conditions and its rarity. Newborn screenings are making it easier to diagnose babies with the disease, allowing for immediate treatment to start. Symptoms of Pompe disease can show up at any age, from infancy to adulthood,…

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Patient-Reported Outcomes Important in Cutaneous GVHD: Study

A longitudinal study involving 436 patients with chronic GVHD found that patients with sclerotic and combination disease had worse symptoms and quality-of-life impairment compared to those with epidermal disease. The study used two validated patient-reported outcome tools to measure these factors. PROs were also found to predict non-relapse mortality for all three disease subtypes, indicating…

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Better Air Quality Reduces Suicide Rates: Study Finds

A new study has found a causal connection between air pollution and suicide rates, particularly affecting elderly women. Researchers from India and the U.S. found that China’s efforts to reduce air pollution have prevented 46,000 suicide deaths over five years. The study suggests that environmental factors, such as air pollution, can have a significant impact…

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Preserving the Pillars: The Vital Role of Independent Primary Care in American Healthcare

Independent primary care physicians and practices are crucial to the American healthcare system, providing personalized care and fostering trust-based relationships with patients. Patients overwhelmingly prefer visiting their primary care physician for routine and preventive care, as they receive higher quality and more personalized treatment. These independent practices also play a vital role in addressing healthcare…

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Lockdown was beneficial for gut health of newborns, Irish research shows

Babies born during pandemic lockdowns had improved gut health and lower rates of allergies, according to Irish research. Public health restrictions during the pandemic positively impacted the gut microbiome of newborns, leading to fewer infections and reduced allergic conditions. The newborns showed higher levels of beneficial microbes, acquired from their mothers, which may protect against…

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With Medical Debt Burdening Millions, a Financial Regulator Steps In to Help

President Obama established the Consumer Financial Protection Bureau in 2010 to prioritize consumer protection over the interests of big banks. The CFPB has shifted its focus to addressing medical debt issues, penalizing collectors, warning providers, and developing rules to remove medical debt from credit reports. This move has faced opposition from collectors and legal challenges….

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