An ion pump tested as a possible method to treat malignant brain tumors
Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumors.
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Browsing Tag
drugs
Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model
Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating…
Listen: J&J’s vaccine pause, how to talk about remote risks, & why we don’t have new drugs…
How do you describe a one-in-a-million risk? What’s heparin-induced thrombocytopenia? And why’s it so hard to find drugs for Covid-19?
We cover all that and more this week on “The Readout LOUD,” STAT’s…
Can biomaterials offer novel therapeutic strategies against COVID-19?
A team of scientists reviews the current and potential impact of the biomaterial sciences on the COVID-19 pandemic.
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The FDA seeks a new way to review old drugs without causing prices to soar
Chuck Peterson of Omaha, Nebraska, recently experienced a swollen, painful knuckle caused by arthritis. He got a prescription for colchicine.
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Ponatinib identified as a potent inhibitor of SARS-CoV2-induced cytokine storm
Researchers at the Human Biology Division, Fred Hutchinson Cancer Research Center in Washington, United States, found that the FDA-approved, multi-kinase inhibitor Ponatinib is a potent inhibitor of the N-terminal domain (NTD) -mediated…
Epilepsy Drugs For Newly Diagnosed Patients: What's Best?
(MedPage Today) -- Valproate (Depakene) emerged as the best first-line choice for generalized epilepsy in a pragmatic study and lamotrigine (Lamictal) as the best first-line treatment for focal epilepsy, British researchers said.
The…
Using genetics, researchers identify potential drugs for early treatment of COVID-19
Credit: Frank Curran
A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages.
The findings appeared online in the journal…
Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections
Experts have uncovered a new molecular reason why faecal transplants are highly effective in treating infections such as C. difficile (a nasty bacteria that can infect the bowel), which could lead to more targeted treatments for this and…
STAT+: Clinical study reports hold more details about the side effects of cancer drugs
For years, researchers have urged regulators to release clinical study reports that are generated during clinical trials in order to support further research and improve care. Now, a new study offers evidence why this is a good idea:…
STAT+: A controversial court case in Brazil will tackle pharma ‘monopolies’ and access to drugs
After years of anticipation, the Brazilian Supreme Court is holding a hearing this week on a case that has pitted the pharmaceutical industry against consumer advocates over patent rights and the extent to which many prescription drugs…
Gold Sensor Lives Under Skin for Months Measuring Drugs and Biomarkers
Researchers at the Johannes Gutenberg University Mainz in Germany have developed an implantable biosensor that can measure concentrations of various biomarkers and drugs in the body. Unlike many implantable devices, the sensor can…
Researchers take key step toward new drugs and vaccines to combat COVID-19
Researchers in the Oregon State University College of Science have taken a key step toward new drugs and vaccines for combating COVID-19 with a deep dive into one protein's interactions with SARS-CoV-2 genetic material.
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Research finds possible explanation for why many cancer drugs don't work in human trials
A possible explanation for why many cancer drugs that kill tumor cells in mouse models won't work in human trials has been found by researchers with The University of Texas Health Science Center at Houston (UTHealth) School of Biomedical…
Synthesis of Michael Adducts as Key Building Blocks for Potential Analgesic Drugs: In vitro, in vivo…
Drug Des Devel Ther. 2021 Mar 23;15:1299-1313. doi: 10.2147/DDDT.S292826. eCollection 2021.ABSTRACTBACKGROUND: Organocatalytic asymmetric Michael addition is a strong approach for C-C bond formation. The objective of the study is to…
Refractory IBD: The Case for Doubling Up on Drugs
(MedPage Today) -- Dual biologic or small molecule therapy may benefit highly selected, refractory inflammatory bowel disease (IBD) patients at specialized centers, a meta-analysis suggested.
In a review of 30 studies reporting on 288…
Could a flavonoid found in common fruit and vegetables combat COVID-19?
Researchers in India have gathered and presented a large body of evidence highlight quercetin – a flavonoid molecule found in many common fruits and vegetables – may be developed into drug therapies used to combat COVID-19.
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Immunotherapy Drugs Industry Assessment 2021 Featuring Comprehensive Profiles of Amgen, Bayer,…
DUBLIN--(BUSINESS WIRE)--The "Immunotherapy Drugs: Global Markets" report has been added to ResearchAndMarkets.com's offering. The global immunotherapy market can be segmented into the following types: checkpoint inhibitors, monoclonal…
Early treatment with anti-VEGF injections slows diabetic retinopathy
Early treatment with anti-VEGF injections slowed diabetic retinopathy in a clinical study from the DRCR Retina Network (DRCR.net). However, two years into the four-year study its effect on vision was similar to standard treatment, which…
A smart viral vector for targeted delivery of hydrophobic drugs
Sci Rep. 2021 Mar 29;11(1):7030. doi: 10.1038/s41598-021-86198-y.ABSTRACTTargeted delivery of hydrophobic chemotherapeutic drugs to tumor cells remains a fundamental problem in cancer therapy. Effective encapsulation of hydrophobic drugs…