Drug

The pandemic has shined a spotlight on the biopharmaceutical industry, proving its value through the speed of vaccine development to a society that ranked it even lower in its esteem than the federal government. But when it comes to…

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating…

In an unusual move, Pacira Biosciences (PCRX) has filed a libel lawsuit against a medical journal, its editors, and the authors of several recently published papers, arguing the articles were based on “faulty scientific…

What You Should Know: – Medable, Inc., a Palo Alto, CA-based global platform for decentralized clinical trials today announced $78M in new funding to fuel advances in the delivery of digital and decentralized clinical…

Metformin inhibits disease progression in non-diabetic chronic kidney disease (ND-CKD) Credit: Professor Hirofumi Kai Researchers from Kumamoto University (Japan) have found that the anti-diabetic drug metformin significantly…

People living with amyotrophic lateral sclerosis, or ALS, in the U.S. will have to wait longer than their counterparts in Europe and Canada for access to a potentially beneficial treatment, even though the medicine is being developed…

DUBLIN--(BUSINESS WIRE)--The "Global Regenerative Medicines Market 2020-2030: Focus on Products, Applications, 17 Countries' Data and Competitive Landscape" report has been added to ResearchAndMarkets.com's offering. The global…

The anti-diabetic drug phenformin may prompt stronger cancer-fighting activities than its sister compound metformin, a finding that could have major implications for current and future clinical trials investigating both agents for their…

For countries in Europe, negotiating a deal with a pharma company over drug prices is the equivalent of a David and Goliath matchup. Payers have little leverage to push back against prices and terms set by pharma companies, causing many…

Editors note: A livestream of the conversation will be embedded below at 1 p.m. ET. Sponsored By   Every week, STAT+ subscribers get access to exclusive conversations with biotech, pharma, and health tech leaders. This week, STAT…

WASHINGTON — Steve Ubl, who leads the drug industry lobbying powerhouse PhRMA, has a bold prediction: Democrats might control the House, Senate, and White House, but Covid-19 has given pharma the advantage in the debate over drug…

Curr Drug Targets. 2021 Apr 12. doi: 10.2174/1389450122666210412125643. Online ahead of print.ABSTRACTBACKGROUND: Chagas disease is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi and is…

Rapid Commun Mass Spectrom. 2021 Apr 9:e9096. doi: 10.1002/rcm.9096. Online ahead of print.ABSTRACTRATIONALE: Low speed and low flexibility of most LC-MS/MS approaches in early drug discovery delay sample analysis from routine in vivo…

In a small phase 2 trial, GM-CSF/sargramostim provided measurable disease-modifying and memory-enhancing benefits in patients with mild-to-moderate Alzheimer's disease. Medscape Medical News Source link

Revolution Medicines on Saturday presented updated data to bolster the case for its lead cancer drug — designed to stop tumor growth by throttling back mutations in a common cell-signaling pathway. The drug, called RMC-4630,…

A Brazilian Supreme Court judge suspended extensions for pharmaceutical patents in the country, and although the decision is only temporary, the move still holds the potential for opening the door to numerous lower-cost generic…

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is rather modest. We have bold plans to train the official…

Adv Exp Med Biol. 2021;1310:533-550. doi: 10.1007/978-981-33-6064-8_20.ABSTRACTDrug metabolism and pharmacokinetics (DMPK) are fundamental in drug discovery. New chemical entities (NCEs) are typically evaluated with various in vitro and…

Int J Nanomedicine. 2021 Apr 1;16:2597-2613. doi: 10.2147/IJN.S295445. eCollection 2021.ABSTRACTINTRODUCTION: Limited by tumor vascular barriers, restricted intratumoural T cell infiltration and nanoparticles accumulation remain major…

The Orphan Drug Act, passed in good faith to help patients with rare diseases in 1983, has been at the center of multiple controversies in recent years. A study published last month in Health Affairs has added fuel to that fire.The key…