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Graphical abstract. Credit: Immunity (2024). DOI: 10.1016/j.immuni.2024.04.006 The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so that the tumor can grow unimpeded by the body’s defenses. The lab’s discovery was published in the paper, “Glucose-driven histone…
More than 1 million Americans live with Crohn’s, a chronic and sometimes crippling inflammatory bowel disease that affects the intestines and leads to digestive issues. While some people may have mild symptoms or even be symptom-free at times, others get severe belly pain, diarrhea, fatigue, weight loss, anemia, and other life-threatening complications. So far, the…
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Credit: Pixabay/CC0 Public Domain New data from the REAL-PE analysis investigated catheter-based pulmonary embolism (PE) treatment, showing women and Black people were less frequently treated with minimally invasive therapy compared to men or non-Black patients. The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions. PE is…
Microbiota therapeutics, such as fecal microbiota transplantation (FMT), could offer more diverse, personalized treatment options for patients with inflammatory bowel disease (IBD), particularly for those with no response or resistance to existing therapies, according to a new review. Treatments that target the microbiome could help when combined with current drugs that alter the immune system,…
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Credit: CC0 Public Domain An analysis of 15 name-brand drugs and their “skinny label” generic counterparts found that competition from these counterparts saved Medicare Part D nearly $15 billion from 2015 to 2021. Skinny labeling allows generic drug manufacturers to exclude labeling information that remains patent-protected by the brand name manufacturer. However, a recent federal…
A global increase in stroke-related death and disability has been linked to extreme temperatures related to climate change, data from a 30-year global study showed. In the first study to assess the global stroke burden attributed to nonoptimal temperatures, investigators found that in 2019, more than 500,000 people around the world died of stroke linked…
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