Scientists discover a key mechanism used by human herpesvirus 8 to induce cancer
Cleveland Clinic researchers have discovered how Kaposi’s sarcoma-associated herpesvirus (KSHV) induces cancer by manipulating human enzymes CDK6 and CAD. This finding has significant implications as viruses cause 10-20% of cancers globally. The study showed that inhibiting the virus’s manipulation of these enzymes with existing drugs could reduce replication, block progression, and shrink tumors in preclinical…