Scientists discover a key mechanism used by human herpesvirus 8 to induce cancer

Cleveland Clinic researchers have discovered how Kaposi’s sarcoma-associated herpesvirus (KSHV) induces cancer by manipulating human enzymes CDK6 and CAD. This finding has significant implications as viruses cause 10-20% of cancers globally. The study showed that inhibiting the virus’s manipulation of these enzymes with existing drugs could reduce replication, block progression, and shrink tumors in preclinical…

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The Science Behind the Increased Risk for Black People

Multiple myeloma, a type of cancer that affects plasma cells, disproportionately affects Black people compared to white people. Some possible reasons for this disparity include genetic factors, such as variations in genes that may make Black individuals more susceptible to the disease. Additionally, health care disparities, such as lack of access to quality medical care…

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FDA OKs First Drug-Coated Balloon for In-Stent Restenosis

The FDA has approved Boston Scientific’s Agent Drug-Coated Balloon (DCB) for the treatment of coronary in-stent restenosis in patients with coronary artery disease. The DCB transfers a therapeutic dose of the antiproliferative drug paclitaxel to the vessel wall to prevent restenosis. The approval was based on positive results from the AGENT IDE trial, which showed…

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EAGLE-1 phase III trial shows

The EAGLE-1 phase III trial demonstrated that gepotidacin has the potential to be a novel oral treatment option for uncomplicated gonorrhoea. This new medication could offer an effective and convenient alternative for patients with this sexually transmitted infection. The study results suggest that gepotidacin may be a promising solution to combat the rising rates of…

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Navigating the Wellness Frontier: Show Me the Science

The famous movie line “Show me the money” from Jerry Maguire serves as a metaphor for the shift towards evidence-based practices in the health and wellness industry. Consumers are now seeking products and practices backed by scientific credibility, driving a convergence between traditional health and wellness sectors. Tele-wellness technologies are bridging the gap between individuals…

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NCHD General Adult Psychiatrists – Temporary Full Time

The NCHD General Adult Psychiatrists position is temporary full-time from July 2024 to July 2025, requiring current Irish Medical Council Registration. Interested applicants can inquire with Sarah Foley or Caitlyn McGoldrick and submit their CVs via email or post by the closing date. The proposed interview date is in the week commencing 8th April 2024….

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Metabolic Syndrome Associated With Risk for Various GI Cancers

The study found a significant association between metabolic syndrome (MetS) and an increased risk for gastrointestinal (GI) cancers. MetS and its components were linked to a higher risk for colorectal, esophageal, gallbladder, liver, and pancreatic cancers. Lifestyle changes or medical interventions targeting MetS patients could be potential prevention strategies for GI cancers. MetS components like…

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Salvo Health secures $5M for digital gastrointestinal care

Salvo Health, a digital gastrointestinal care startup, recently closed a $5 million Seed Prime round led by City Light Capital and Human Ventures. The company’s existing investors, including Torch Capital, Threshold Ventures, and Felicis Ventures, also participated in the round. Salvo Health offers a virtual clinic for chronic gastrointestinal and metabolic liver issues, providing wraparound…

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