Cellular

Related Articles HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow. Sci Rep. 2021 Jan 14;11(1):1468 Authors: Boehme JT, Morris CJ,…

Researchers have identified a pathway involving a protein called Rab35 in glioblastoma brain cancer. The study reports restoring the activity of Rab35 could have therapeutic benefits for those with glioblastoma. Source link

Related Articles Monitoring the Cellular Delivery of Doxorubicin-Cu Complexes in Cells by Fluorescence Lifetime Imaging Microscopy. J Phys Chem A. 2020 May 28;124(21):4235-4240 Authors: Peng Z, Nie K,…

Histologic and clinical improvement of sun-exposed skin following topical treatment with retinoic acid has been reported. Daily application of retinoic acid typically results within 2–5 d in an erythematous scaling reaction, which…

Nowsheen Mullani, Yevheniia Porozhan, Adèle Mangelinck, Christophe Rachez, Mickael Costallat, Eric Batsché, Michele Goodhardt, Giovanni Cenci, Carl Mann, Christian Muchardt RNAs originating from transcription upstream and downstream of…

Related Articles Cellular and molecular pathobiology of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2021 Jan 11;: Authors: Mishra S, Kass DA Abstract Heart failure…

To investigate the histogenesis of lymphomatoid papulosis (LYP), we have analyzed the configuration of the β, γ, and δ T-cell receptor (TCR) and Ig genes in DNA from 31 biopsies of 18 patients with this condition and also from peripheral…

Since the confirmation of cellular senescence as an important contributing cause of aging, a great many research initiatives have focused on the biochemistry of senescent cells, in search of new approaches to rejuvenation therapies. A…

BOSTON--(BUSINESS WIRE)--Gamida Cell Ltd. (Nasdaq: GMDA), an advanced cell therapy company committed to cures for blood cancers and serious hematologic diseases, today announced that the full results of the Phase 3 clinical trial of…

Chronic exposure to UVR is known to disrupt tissue homeostasis, accelerate the onset of age-related phenotypes, and increase the risk for skin cancer—a phenomenon defined as photoaging.In this paper, we review the current knowledge on…

Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition Source link

Related Articles Blood pressure changes PVAT function and transcriptome: use of the mid-thoracic aorta coarcted rat. Am J Physiol Heart Circ Physiol. 2020 12 01;319(6):H1313-H1324 Authors: Contreras…

Observational clinical research of COVID-19 patients can help clinicians better understand how the previously unknown SARS-CoV-2 virus acts, and findings from this research can better inform treatment and vaccine design. Credit: UAB …

COVID-19, which has killed 1.7 million people worldwide, does not follow a uniform path. Source link

Evidence has accumulated in recent years for the accumulation of senescent cells in aged tissues to be an important driver of fibrosis, particularly the evidence resulting from studies that employed senolytic therapies to selectively…

Ana Gabriela Jimenez, Cynthia J. Downs, Sahil Lalwani, and William Cipolli Source link

Ana Gabriela Jimenez, Cynthia J. Downs, Sahil Lalwani, and William CipolliThe immune system undergoes marked changes during aging characterized by a state of chronic, low-grade inflammation, so called inflammaging. Domestic dogs are the…

Researchers have identified a direct cellular interaction between the nervous system and the immune system. Pain sensing neurons around the lymph nodes can modulate lymph node activity. Source link

Cellular reprogramming can reverse the aging that leads to a decline in the activities and functions of mesenchymal stem/stromal cells (MSCs). This is something that scientists have known for a while. But what they had not figured out is…

by Ryan Houston, Shiori Sekine, Michael J. Calderon, Fayaz Seifuddin, Guanghui Wang, Hiroyuki Kawagishi, Daniela A. Malide, Yuesheng Li, Marjan Gucek, Mehdi Pirooznia, Alissa J. Nelson, Matthew P. Stokes, Jacob Stewart-Ornstein, Steven…