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Torsemide, Furosemide Have Similar Outcomes in Patients Discharged With Acute HF

The TRANSFORM-HF study found no significant difference in outcomes between torsemide and furosemide treatments for heart failure. However, patients with de novo heart failure had better outcomes compared to those with worsening chronic heart failure after hospitalization. The study analyzed patients from 60 US hospitals and found that de novo heart failure was associated with…

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Readout LOUD podcast: live from JPM 2024

The content is about the latest in the biotech industry, discussed in a podcast called “The Readout LOUD” from STAT. The podcast covers the recent turnaround in the biotech industry, with deals and positive developments at the J.P. Morgan Healthcare Conference. It also delves into topics such as the Sarepta Therapeutics saga, Nvidia’s potential impact…

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Labour launches child action plan to create “healthiest generation ever”

Labour has unveiled a child action plan aimed at creating the healthiest and happiest generation in Britain. The plan includes reducing paediatric waiting times, improving child mental health support, addressing junk food advertising, and implementing supervised toothbrushing in schools. A Labour government would establish a mission delivery board focusing on child health and inequalities. Keir…

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American Heart Association’s merit award recipients announced

The American Heart Association is celebrating 100 years by awarding its prestigious Merit Award to three researchers. Joseph Loscalzo will study natural food chemicals and their impact on heart disease. Daniel J. Rader will investigate lipid metabolism and cardiovascular diseases, while Philip S. Tsao will focus on the effects of vaping on abdominal aortic aneurysms….

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Insulin Injections at Home: What to Expect

Diabetes management with insulin involves learning to give yourself injections. Kathy Bostrom emphasizes the rapid changes in syringes and pens which have made the process easier. Syringes are prone to errors, while pens are more user-friendly. An alcohol wipe is essential while also having a sharps container. Different insulins require different times for their administration…

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Death of a Sibling Increases the Risk for Heart Disease

A new study published in JAMA Cardiology suggests that people who have experienced the death of a sibling may be at an increased risk of developing cardiovascular illnesses. The study, which analyzed data from over 2 million people in Denmark, found that individuals who lost a sibling had a 17% higher risk for overall cardiovascular…

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Elevance Health To Offer Smartphones to Some Medicaid Members

Elevance Health has partnered with Samsung, Verizon, AT&T, and T-Mobile to provide Medicaid members with smartphones and unlimited data, talk, and text at no cost. The program aims to improve access to virtual healthcare tools and bridge the digital divide for low-income individuals. The initiative is funded by the Federal Communications Commission’s Affordable Connectivity Program…

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GP required to join north Dublin city practice

A Dublin-based GP practice on the north side of the city is looking for a GP to join their team. The practice focuses on providing high-quality patient care in a sustainable work environment, serving approximately 5,200 patients. They are open to integrating new skills and have the support of the local hospital to develop skills…

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Suicide prevention telehealth provider Vita Health receives $22.5M

Connecticut-based Vita Health has raised $22.5 million in Series A funding, with participation from various investors. The telehealth platform connects individuals contemplating suicide with providers and offers teletherapy and psychiatry services. The funding will support the company’s expansion to help address the increasing rate of suicides in the U.S. Vita Health aims to tackle the…

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Consider complete pathology, surgical techniques for tibial plateau fractures

Surgeons should consider the 3D orientation of tibial plateau fractures before fixation. Understanding the fracture pathology and components is crucial in treatment, including the size and orientation of the fracture, which dictates the location of the medial plate. Methods of articular elevation depend on the degree of comminution and depression, and reducing varus medial column…

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U.K. sequencing study surfaces new findings about tumor DNA

The UK’s 100,000 Genomes Project has revealed that certain tumors are more likely to carry mutations that can inform patient care, steering treatment choices or indicating a potential familial risk. The findings from over 13,800 solid tumors in adults are already influencing clinical practice in the UK’s National Health Service, with patients diagnosed with certain…

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“Safer supply” alternatives to toxic unregulated drug markets

Adam Holland, Thomas D Brothers, Dan Lewer, Olivia M Maynard, and Mat Southwell address the urgent need for action to reduce drug-related deaths. They discuss the prescription of safer supply interventions in response to opioid toxicity and the COVID-19 pandemic in Canada. Despite controversy and concerns about limited evidence, observational studies show that opioid dispensation…

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Pangolins’ genetic makeup linked to increased coronavirus susceptibility

A study published in Scientific Reports suggests that pangolins are highly susceptible to coronavirus infection due to the pseudogenization of key immune system genes in their genome. Researchers analyzed pangolin skin and found that the host immune response pathways were not upregulated in response to infection. They also discovered that the coronavirus suppresses endogenous retrovirus…

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How Does Too Much Sugar Affect Your Body?

The average American consumes about 17 teaspoons of added sugar each day, and sugary drinks, candy, baked goods, and sweetened dairy are the main sources of added sugar. Excess sugar intake can lead to various health issues, including mood changes, joint pain, skin aging, liver damage, heart disease, diabetes, kidney damage, weight gain, and erectile…

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FDA Rejects GI Cancer Drug Over Manufacturing Issues

The FDA has rejected approval of the cancer drug zolbetuximab due to manufacturing issues. The drug, developed by Astellas, was intended for treating a specific type of gastric cancer. The FDA’s decision was related to unresolved deficiencies in the manufacturing process at a third-party facility. The company is working to resolve the issues and clarified…

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Expert Offers Tips To Fight Off Cold And Flu

To stay healthy as temperatures drop and flu season lingers, focus on maintaining a nutritious diet. Nutrition expert Bonnie Taub-Dix recommends incorporating immunity-boosting foods rich in vitamin C, omega-3 fatty acids, and lean protein, including garlic, ginger, colorful fruits and veggies, seafood, and yogurt. Warm soups and herbal teas with immune-supporting properties like elderberry, echinacea,…

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MedCity News is Accepting Applications for the Healthcare Startup Pitch Perfect Contest in Chicago

Healthcare startups in health tech, diagnostics, medtech, and biotech are invited to apply for the MedCity News startup pitch contest at the INVEST conference in Chicago on May 21-22. The contest has four tracks focusing on oncology, cardiology, women’s health, and addressing burnout and operational efficiency. Six finalists will be chosen for each track to…

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Oral SERDs Provide PFS Benefit in HR+, HER2- Advanced Breast Cancer

A meta-analysis supports the use of oral selective estrogen receptor degraders (SERDs) for patients with hormone receptor (HR)-positive, HER2-negative advanced breast cancer. The analysis showed a significant improvement in progression-free survival (PFS) with oral SERDs over standard endocrine therapy in patients who had previously received at least 1 line of endocrine therapy. Oral SERDs significantly…

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Eisai harnesses wearables data for AI-led Alzheimer’s prediction

Japanese pharmaceutical company Eisai and Oita University have developed an AI model that uses data from wearable devices to predict Alzheimer’s disease. The study collected data from 122 individuals aged 65 and older, including physical activity, sleep, heart rate, and lifestyle information. Participants also underwent annual amyloid PET examinations to detect the accumulation of amyloid-beta…

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Mammography AI Can Cost Patients Extra. Is It Worth It?

Some radiology clinics in the U.S. are offering AI analysis of mammograms for an extra $40, which isn’t covered by insurance. The analysis uses AI to detect abnormalities that human radiologists might miss and has the potential to improve the detection of suspicious breast masses and lead to earlier diagnoses of breast cancer. While studies…

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Scarlett McNally: My trust has shown how doctors’ assistants can help support clinicians

Scarlett McNally, a professor and orthopaedic surgeon, highlights several issues in the healthcare system, particularly in the NHS. These issues include backlogs, overworked staff, lack of time, and administrative burdens on doctors. She argues that introducing administrative roles like doctors’ assistants could help doctors use their time more productively. McNally suggests that more support staff…

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Nicotine beliefs elicit dose-response reactions in human brains

A recent study published in Nature Mental Health investigates whether nicotine-related beliefs influence brain processes in a dose-dependent manner. Researchers examine the influence of perceived nicotine dose on the human brain, using nicotine as a test case. The study finds that beliefs about nicotine strength can elicit dose-dependent responses in specific areas of the brain,…

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Take Action After Diagnosis with HER2-Positive Breast Cancer

Advocating for yourself when diagnosed with HER2-positive breast cancer is crucial. Janet Shomaker’s experience with the diagnosis and treatment of HER2-positive breast cancer highlights the importance of being “responsibly selfish” and taking control of your treatment plan, while allowing friends and family to support you. Cancer experts emphasize the need to learn from trusted sources,…

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Low Rate of Aspiration With GLP-1s During Upper GI Endoscopy

New data from Mayo Clinic shows a low rate of pulmonary aspiration during upper gastrointestinal endoscopy in patients taking GLP-1 receptor agonists. Researchers analyzed 4134 procedures and found only two definite cases of pulmonary aspiration, resulting in a cumulative incidence of 4.8 per 10,000 procedures. Both cases occurred under monitored anesthesia care and the patients…

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At JPM, Top GSK Cancer Executive Talks Drug Targets and Oncology Strategy

GSK has committed $270 million to gain access to early-stage assets in the cancer therapy class of antibody drug conjugates. After divesting its oncology business in 2015, the company has decided to re-enter the field, focusing on therapeutic modalities like immuno-oncology, synthetic lethality, and tumor cell targeting. They are prioritizing hematological malignancies, gynecological cancers, lung…

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Amazon announces Health Condition Programs for digital health access

At the JPM Healthcare Conference, Amazon announced the launch of its new Health Condition Programs, allowing customers to access digital health benefits through their employer or insurance carrier. Chronic care management company Omada Health is the launch partner, offering services for conditions such as diabetes and high blood pressure. Omada focuses on data-driven behavior change…

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Will CMS Crack Down on Prior Authorization?

Doctors and patients in the US are frustrated with the prior authorization process required by health insurance companies. Medicare Advantage insurers had to process an average of 1.5 prior authorization requests per patient in 2021. Legislation to regulate prior authorization has strong support from lawmakers, but a bill has not yet passed Congress. The Centers…

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COVID-19 pandemic delayed socio-emotional development in young children

A study published in JAMA Pediatrics found that infants and toddlers experienced socio-emotional development delays during the COVID-19 pandemic. The study included 60,171 families enrolled in the Nurse-Family Partnership (NFP) between 2015 and 2021. The researchers examined the impact of COVID-19 on children’s socioemotional development, finding that all pandemic cohorts had higher odds of positive…

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