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Uganda declares end of 6th Ebola outbreak

, 2025-04-26 18:50:00 Credit: Unsplash/CC0 Public Domain Uganda declared the end of an Ebola virus outbreak Saturday, which has killed at least two people in the east African nation since late January. The announcement came 42 days after the discharge of the last confirmed patient from hospital. The outbreak marked the sixth time Uganda was…

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New Medicare program could dramatically improve affordability for cancer drugs—if patients enroll

, 2025-04-26 18:00:00 Credit: Unsplash/CC0 Public Domain Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000—until recently. Thanks to changes in Medicare Part D introduced by the Inflation Reduction Act (IRA) that took effect in 2025, annual out-of-pocket drug costs for all beneficiaries…

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Young adults drive historic decline in smoking

, 2025-04-25 16:02:00 Since the 1950s, when researchers first linked smoking to lung cancer, national smoking rates have dropped dramatically. Credit: Matthew Stone/John Pierce, UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science Researchers at University of California San Diego found that cigarette smoking continues to decline across the United States,…

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Anti-obesity drugs in the pipeline

Andrew (Drew) Rhoades; Harold E. Bays, MD, FOMA, FTOS, FACC, FASPC, FNLA , 2025-04-26 15:43:00 April 26, 2025 2 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted…

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Why our waistlines expand in middle age—aging stem cells shift into overdrive

, 2025-04-25 16:10:00 Adipogenesis contributes to age-related visceral adipose tissue accumulation. Credit: Science (2025). DOI: 10.1126/science.adj0430 It’s no secret that our waistlines often expand in middle age, but the problem isn’t strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases. Exactly how…

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Surgery May Be Best for Older Patients With Cholecystitis

, 2025-04-25 09:59:00 TOPLINE: Surgical treatment of acute cholecystitis in older patients with multiple comorbidities was linked to lower rates of readmissions and emergency department (ED) revisits than nonoperative treatment, challenging the convention that these patients are “too sick” for surgery. METHODOLOGY: Acute cholecystitis in older patients with multiple health issues is linked to a…

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Serotonin system’s hidden complexity may reshape understanding of day-to-day decision making

, 2025-04-25 16:16:00 Habenula input to raphe triggers direct excitation and heterosynaptic inhibition in 5-HT neurons. Credit: Nature Neuroscience (2025). DOI: 10.1038/s41593-025-01912-7 Our lives are filled with binary decisions—choices between one of two alternatives. But what’s really happening inside our brains when we engage in this kind of decision making? A University of Ottawa Faculty…

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Cannabis Hospitalization Linked to Increased Dementia Risk

, 2025-04-25 10:21:00 TOPLINE: Cannabis-related emergency department (ED) visits or hospitalizations increased more than 26-fold over a 13-year period among individuals aged 65 years or older and were associated with a significantly higher risk of dementia than visits for all-cause acute care, a new study showed. METHODOLOGY: This population-based, retrospective, matched cohort study included data…

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Study illuminates a general principle of neural processing in the brain’s serotonin system

, 2025-04-26 02:37:00 Our lives are filled with binary decisions – choices between one of two alternatives. But what’s really happening inside our brains when we engage in this kind of decision making? A University of Ottawa Faculty of Medicine-led study published in Nature Neuroscience sheds new light on these big questions, illuminating a general principle of neural…

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Can Curing Infections Help Prevent Cancer?

, 2025-04-25 10:52:00 The session titled “Defeating Cancer by Curing Infections” at European Society of Clinical Microbiology and Infectious Diseases Global 2025, held in Vienna, Austria, was led by Catharina Alberts, PhD, from the World Health Organization’s International Agency for Research on Cancer, and Francesco Negro, MD, emeritus professor, formerly at the Department of Medicine…

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Definitely, Photoprotection Is Required in Childhood

, 2025-04-25 11:03:00 “Do children need photoprotection? Definitely yes,” stated Henry W. Lim, MD, former director of the Department of Dermatology at Henry Ford Health in Detroit, former president of the American Academy of Dermatology, and current president of the International League of Dermatological Societies, during a presentation at The World Congress of Pediatric Dermatology…

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Insights could lead to tailored treatments

, 2025-04-25 16:30:00 DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH Researchers using next-generation DNA sequencing have identified four specific genes whose mutations are linked to the development and progression of lethal stomach cancers. This could potentially enable doctors to offer targeted treatments that would spare many patients…

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Computational biology uncovers RNA changes in ALS patients

, 2025-04-26 03:04:00 Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the United States are affected, and doctors still don’t know what causes it. To lay the groundwork for better tests, Thomas Jefferson University researchers Phillipe Loher, Eric Londin, PhD, and Isidore Rigoutsos, PhD are…

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Cancer Deaths Down, but Incidence Rates Vary

, 2025-04-25 11:17:00 Overall cancer deaths in the United States continue to decline, but trends are mixed when it comes to deaths associated with specific cancer types and overall cancer incidence, according to the 2025 Annual Report to the Nation on the Status of Cancer. The report — a joint initiative of the National Cancer…

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STAT readers respond to a viral essay on animal wellness

Torie Bosch , 2025-04-26 11:00:00 First Opinion is STAT’s platform for interesting, illuminating, and provocative articles about the life sciences writ large, written by biotech insiders, health care workers, researchers, and others. To encourage robust, good-faith discussion about issues raised in First Opinion essays, STAT publishes selected Letters to the Editor received in response to…

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DNA changes in umbilical cord blood could provide clues to preventable health issues later in life

, 2025-04-25 16:38:00 Credit: Pixabay/CC0 Public Domain The umbilical cord may become a crystal ball of sorts, helping doctors predict the future of children at risk for long-term health problems, including diabetes, stroke, and liver disease. DNA changes found in cord blood could offer early clues about which infants are at higher risk—opening the door…

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Distinct subtypes of senescent skin cells identified

, 2025-04-26 04:01:00 Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.  New findings may explain why: Not all senescent skin…

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ACP Initiatives Boost Reach, Effectiveness in Primary Care

, 2025-04-25 11:33:00 TOPLINE: Advance care planning (ACP) strategies, such as adding ACP coordinators and using the Lightning Report Facilitation, improved patient outcomes in primary care clinics in Nebraska, with an increase noted in the reach of ACP discussions. METHODOLOGY: Researchers conducted a mixed-methods study at two Nebraska primary care sites, focusing on two strategies…

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Global survey highlights the challenges of VR-haptic technology in dental education

, 2025-04-25 16:39:00 Credit: Pixabay/CC0 Public Domain A recent global survey of 156 institutions reveals strong interest in VR-haptic technology for dental training, yet significant barriers impede widespread adoption. The study was led by the University of Eastern Finland and published in Frontiers in Dental Medicine. Combining virtual reality with force feedback, VR-haptic technology is…

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A Risky Side Effect of Certain Cancer Drugs

, 2025-04-25 11:40:00 The October 2024 approval of inavolisib for advanced breast cancer spotlighted a growing problem in breast oncology: Managing the hyperglycemia caused by phosphoinositide 3-kinase (PI3K)/Akt pathway inhibitors. Inavolisib is one of a growing class of inhibitors targeting the PI3K/Akt pathway in certain patients with advanced or metastatic breast cancer. Targeting the pathway,…

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Study identifies how malaria can lead to childhood cancer

, 2025-04-25 16:45:00 Credit: Pragyan Bezbaruah from Pexels New data published in The Journal of Immunology has revealed the role of Plasmodium falciparum infection (malaria) in the development of Burkitt lymphoma (BL), the most common childhood cancer in equatorial Africa and New Guinea. BL has been associated with P. falciparum malaria since 1958, but the…

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BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

, 2025-04-26 04:26:00 BioSkryb Genomics and Tecan Group, today introduced a high-throughput single-cell workflow, combining BioSkryb’s 384-well format of the ResolveOME™ Whole Genome and Transcriptome Single-Cell Core Kit with the Uno Single Cell Dispenser™, provided by Tecan. The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for…

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Cobenfy Falls Short as Add-On Therapy for Schizophrenia

, 2025-04-25 11:41:00 Adjunctive use of xanomeline/trospium chloride (Cobenfy) offered no statistically significant benefit over placebo in adults with symptoms of schizophrenia inadequately controlled by an atypical antipsychotic, according to top-line results from the phase 3 ARISE study. However, adjunctive use of the first-in-class antipsychotic did show a numerical improvement compared with treatment with placebo…

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Understanding the motivations behind cancer patients’ adoption of traditional Chinese medicine

, 2025-04-26 04:45:00 Background and objectives Traditional Chinese medicine (TCM) is widely used in cancer care in China as an integral part of treatment. This study aimed to understand the motivations of cancer patients in China for adopting TCM in their treatment and to examine their communication with oncologists. Gaining insights into these factors can…

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Memory, Mood Symptoms Form Feedback Loop in Older Adults

, 2025-04-25 12:00:00 TOPLINE: Depression and loneliness predicted memory decline over time in older adults, while memory decline worsened mood symptoms, according to a new study that highlighted a bidirectional link among these variables. METHODOLOGY: Researchers aimed to study longitudinal relationships among immediate memory, depressive symptomatology, and loneliness, while controlling for age and the number…

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