Andrew Joseph , 2025-04-28 07:17:00 Andrew Joseph covers health, medicine, and the biopharma industry in Europe. You can reach Andrew on Signal at drewqjoseph.45. After months of discussion, Germany’s Merck KGaA said Monday it would buy SpringWorks Therapeutics for $47 a share in cash, a deal with an equity value of nearly $4 billion. The…
, 2025-04-28 07:00:00 Credit: Unsplash/CC0 Public Domain A recent randomized controlled trial reveals the potential of a program designed to connect patients who have breast cancer to needed exercise and rehabilitation services starting at diagnosis and throughout care. Participants provided positive feedback about the program, supporting efforts to integrate exercise and rehabilitation services as part…
, 2025-04-28 07:04:00 TOPLINE: Investigators have identified a range of risk factors that significantly increase the odds of late-onset epilepsy (LOE) in people with cognitive decline (PWCD), including having the apolipoprotein E4 (APOE4) allele, early-onset dementia, severe cognitive decline, the Alzheimer’s disease (AD) dementia subtype, a history of stroke or transient ischemic attack (TIA), and…
, 2025-04-28 06:42:00 Childhood obesity sets the stage for a lifetime of health risks, and scientists are racing against time to uncover the hidden causes. Now, new research points to an unexpected suspect: antibiotics, a medicine millions of people, including young children, take to fight infections, may be quietly fueling the problem. Although antibiotics are…
, 2025-04-28 06:03:00 TOPLINE: Patients with cancer who received prophylactic intravenous (IV) magnesium before starting cisplatin had a lower risk for cisplatin-associated acute kidney injury (AKI) than those who did not receive IV magnesium. METHODOLOGY: AKI is a frequent and serious complication of cisplatin chemotherapy and is associated with poor outcomes. Although preclinical studies have…
, 2025-04-28 06:00:00 A graphic showing the three types of ‘bad cholesterol’ lipoprotein carriers which all contain the apoB particle as a defining structural feature. Credit: Chalmers University of Technology | Jakub Morze For almost 60 years, measuring cholesterol levels in the blood has been the best way to identify individuals at high risk of…
, 2025-04-28 02:35:00 Numerous studies conducted by researchers at Dana-Farber Cancer Institute report progress for cancers including head and neck cancer, metastatic breast cancer and lung cancer. The results of these studies, along with dozens of others led by Dana-Farber faculty, will be presented at this year’s American Association for Cancer Research (AACR) Annual Meeting…
, 2025-04-28 02:38:00 Healthcare practitioners from around the world received hands-on training for treating patients in cardiogenic shock (CS) during a first-ever simulation lab at today’s Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplantation (ISHLT) in Boston. The simulation lab was part of ISHLT’s inaugural Cardiogenic Shock Academy, a…
, 2025-04-28 05:10:00 TOPLINE: Statin use in chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) patients showed significant survival benefits, with a 45% lower risk for overall mortality and 27% reduced risk for disease progression. Benefits remain consistent across treatment types, with no increase in severe adverse effects. METHODOLOGY: Individual participant data were pooled…
, 2025-04-28 04:00:00 Credit: CC0 Public Domain An infectious disease detection platform developed by University of Pittsburgh scientists working with UPMC infection preventionists proved over a two-year trial that it stops outbreaks, saves lives and cuts costs. The results are published in the journal Clinical Infectious Diseases, making the case for adoption in hospitals nationwide…
, 2025-04-28 04:16:00 New research reveals that ultra-processed foods account for nearly half of US household grocery purchases, with lower-income and less-educated families bearing the brunt, underscoring the need for urgent national policy reform. Study: Exploring disparities in the proportion of ultra-processed foods and beverages purchased in grocery stores by US households in 2020. Image…
, 2025-04-28 04:10:00 Credit: Unsplash/CC0 Public Domain A study analyzing data from nationally representative dietary surveys and mortality data from eight countries (Australia, Brazil, Canada, Chile, Colombia, Mexico, United Kingdom, and United States) shows that premature deaths attributable to consumption of ultraprocessed foods (UPFs) increase significantly according to their share in individuals’ total energy intake….
, 2025-04-28 02:42:00 In places like Australia, where metropolitan areas are separated by an entire continent, donor hearts used to go unused simply because transplant teams couldn’t get the organ to a recipient in time. If there isn’t a recipient for an available heart in Perth but there’s a match in Sydney, that’s nearly…
, 2025-04-28 03:38:00 TOPLINE: A systematic review identified a prevalence range of tinea pedis in children from 0.03% to 15.6%, with notable demographic and geographic variations. Dermatophytes, particularly Trichophyton rubrum, were the most common causative agents. METHODOLOGY: To evaluate the prevalence of tinea pedis in children aged 0-19 years, the researchers conducted a systematic review…
, 2025-04-28 02:48:00 A study on donor lungs preserved outside the body before transplantation demonstrated that the hypothermic oxygenated machine perfusion (HOPE) technique is a safe and effective lung preservation method, even with total out-of-body times approaching 20 hours. Jitte Jennekens, MSc, organ perfusionist/transplant coordinator at the UMC Utrecht in the Netherlands, presented the study…
, 2025-04-28 03:05:00 A century after early warnings, researchers now fear that yellow fever could erupt beyond its historical strongholds, posing an unprecedented threat to billions in the Asia-Pacific and beyond. Study: Yellow Jack: a modern threat to Asia-Pacific countries? Image Credit: nechaevkon / Shutterstock A recent study published in the journal npj Viruses proposed that global…
, 2025-04-28 02:53:00 Patients with locally advanced head and neck cancer who received the immune checkpoint inhibitor pembrolizumab before, during and after standard-of-care surgery had longer event-free survival without the cancer coming back and higher rates of substantial tumor shrinkage prior to surgery, according to the first interim analysis of a randomized, open-label phase 3…
, 2025-04-28 02:46:00 Researchers at the Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplantation (ISHLT) marked the 10-year anniversary of modern heart donation after circulatory death (DCD), a technique that has significantly increased transplant volumes around the world. Sarah Scheuer, MD, PhD, said that most centers that have started…
, 2025-04-28 02:09:00 New projections warn that measles could once again become a permanent fixture in the U.S. unless vaccination rates improve, highlighting the urgent need to bolster immunization efforts amid rising vaccine hesitancy. Image Credit: Lightspring / Shutterstock In a recent study published in the JAMA (The Journal of the American Medical Association), researchers utilized nearly…
, 2025-04-28 01:30:00 A new perspective highlights how Brexit has fractured the UK’s food system, exposing vulnerabilities and ushering in new economic strategies that threaten food access, resilience, and public health. Perspective: The Impact of Brexit on UK Food Standards and Food Security: Perspectives on the Repositioning of Neoliberal Food Policy. Image Credit: Mhai Little Arts /…
, 2025-04-28 00:44:00 Daily communication can make or break relationship satisfaction for FIFO workers separated from their partners, new research shows, offering industries a roadmap to better support worker wellbeing. Study: Communication and relationship satisfaction of Fly-in, Fly-out workers and partners. Image Credit: Adwo / Shutterstock Researchers from Central Queensland University reveal that the relationship satisfaction of…
Helen Branswell , 2025-04-27 23:11:00 Confusion over the Food and Drug Administration’s delay in granting full approval to Novavax’s Covid-19 vaccine deepened over the weekend when the agency’s commissioner, Marty Makary, took to social media to defend the FDA’s controversial handling of the company’s submission. In the process, Makary and a spokesman for the Department…
Sara Kellner , 2025-04-27 20:51:00 April 27, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Angus Chen and Matthew Herper , 2025-04-27 20:52:00 You’re reading the web edition of AACR in 30 Seconds, STAT’s guide to the American Association for Cancer Research annual meeting. Sign up for email here. AACR’s big annual meeting began as usual with its large opening ceremony, but AACR CEO Margaret Foti’s closing remarks were very much…
, 2025-04-27 20:11:00 Neurology student Henriette Dieng examines Abdou Diop, a patient with genetic neuropathy at Pedro Rodriguez’s clinic in Dakar, Senegal, Friday, Jan. 10, 2025. Credit: AP Photo/Annika Hammerschlag Ndeye Lam visits the cemetery often, praying and gently touching the seashells laid out across her daughter’s gravesite. “Mariama will always be here,” she said,…
, 2025-04-27 20:12:00 Credit: Unsplash/CC0 Public Domain Sierra Leone is facing an increase in recorded mpox infections, with 177 new cases reported in recent days, a health ministry official told AFP. The West African country, which in January declared a public health emergency to combat mpox, has sent health teams to carry out screening operations…
, 2025-04-27 19:50:00 Credit: Pixabay/CC0 Public Domain A study on donor lungs preserved outside the body before transplantation demonstrated that the hypothermic oxygenated machine perfusion (HOPE) technique is a safe and effective lung preservation method, even with total out-of-body times approaching 20 hours. Jitte Jennekens, MSc, organ perfusionist/transplant coordinator at the UMC Utrecht in the…
Eamon N. Dreisbach , 2025-04-27 18:30:00 April 27, 2025 1 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . ” data-action=subscribe> Subscribe We were unable to process your request. Please try again…
, 2025-04-27 18:00:00 Credit: PARINDA SHAAN from Pexels At today’s Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) in Boston, Angela Lorts, MD, MBA, issued an urgent call for improved mechanical circulatory support (MCS) devices for children with life-threatening heart conditions. “Advances in pediatric cardiac disease are underfunded…
, 2025-04-27 17:00:00 Credit: Pixabay/CC0 Public Domain Researchers at the Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplantation (ISHLT) marked the 10-year anniversary of modern heart donation after circulatory death (DCD), a technique that has significantly increased transplant volumes around the world. Sarah Scheuer, MD, Ph.D., said that most…
Nancy Hemphill, ELS, FAAO , 2025-04-27 16:48:00 April 27, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable…
Sara Kellner , 2025-04-27 15:09:00 April 27, 2025 2 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Anthony DeFino , 2025-04-27 14:53:00 April 27, 2025 1 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Joe Graw , 2025-04-27 14:34:00 You arrive at the scene to find a patient struggling to breathe. They can’t speak clearly, no family is present, and no one knows their medical history. What medications are they on? Do they have life-threatening allergies? Are they diabetic, asthmatic, or recovering from surgery? EMS providers face situations like…
, 2025-04-27 14:30:00 Credit: Pixabay/CC0 Public Domain In places like Australia, where metropolitan areas are separated by an entire continent, donor hearts used to go unused simply because transplant teams couldn’t get the organ to a recipient in time. “If there isn’t a recipient for an available heart in Perth but there’s a match in…
Dr. Caroline Carney , 2025-04-27 13:34:00 The connection between climate and physical health is evident. We know, for instance, that asthma is exacerbated by exposure to wildfire smoke that occurs more commonly during hot, dry, windy conditions. Heat stroke is also a well-known outcome of exposure to heat and dehydration. Now, an equally urgent narrative…
Katie Adams , 2025-04-27 13:59:00 Hospitals experienced a severe drop in M&A activity during the first quarter of 2025. There were only five transactions during the quarter — and zero mega-mergers (deals where the smaller party’s revenue is $1 billion or more). Compare this to the first quarters of 2024 and 2023, which had 20…
Frank Vinluan , 2025-04-27 13:35:00 Compounded versions of Novo Nordisk’s Wegovy and Ozempic will need to stop production soon. Lawsuits over these products are ongoing, but a federal court ruling in Texas means that compounding pharmacies can’t keep making their products as the legal process continues. The April 24 order by U.S. District Court Judge…
, 2025-04-27 13:30:00 Vaccination and sampling schedule for RV456/EBL2003 Phase 2 Ad26/MVA Ebola vaccine trial. Credit: Science Translational Medicine (2025). DOI: 10.1126/scitranslmed.adq2496 Filoviruses are among the globe’s most lethal—indeed, so dangerous they can be handled only in high-security laboratories. Yet, more than five decades after the discovery of the Marburg virus and nearly 50 years…
Gerard Gallagher , 2025-04-26 23:45:00 April 26, 2025 3 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Alex Young , 2025-04-26 21:46:00 April 26, 2025 1 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process…
Andrew (Drew) Rhoades; Christos S. Katsanos, PhD , 2025-04-26 20:36:00 April 26, 2025 2 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe …
Eamon N. Dreisbach , 2025-04-26 20:37:00 April 26, 2025 1 min read Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to…
Angus Chen and Matthew Herper , 2025-04-26 20:48:00 You’re reading the web edition of AACR in 30 Seconds, STAT’s guide to the American Association for Cancer Research annual meeting. Sign up for email here. Welcome to STAT’s annual newsletter covering the meeting of the American Association for Cancer Research. We’re glad you’re here. AACR is…
, 2025-04-25 15:32:00 RSV infects human iPS cell–derived respiratory organoids. Credit: Life Science Alliance (2025). DOI: 10.26508/lsa.202402837 A study by former Junior Associate Professor Kazuo Takayama, currently a professor of the Institute of Science Tokyo, demonstrates the potential of human iPS cell-derived respiratory organoids as an effective model for studying respiratory syncytial virus (RSV) infections….
Anthony Wallace; Anthony DeFino , 2025-04-26 19:58:00 April 26, 2025 2 min watch Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable…
, 2025-04-25 15:36:00 Scheme of immuno-infrared sensor (iRS). Credit: EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00229-z Parkinson’s disease is a neurodegenerative disorder that is usually diagnosed in its late stage on the basis of clinical symptoms, mainly motor disorders. By this point, however, the brain is already severely and irreparably damaged. Moreover, diagnosis is difficult and…
, 2025-04-25 15:40:00 by I. Edwards Health officials in California are now offering gift cards to encourage folks near farms to get tested for bird flu. The project is a partnership between the state and the U.S. Centers for Disease Control and Prevention (CDC), according to CBS News. Clinics run by a state vendor near…
, 2025-04-25 15:47:00 Images from the research paper show an increase in neurogenesis (as indicated by two markers: Ki67 and EdU) in mice exposed to 40Hz stimulation compared to those exposed only to ambient light and sound. Yellow arrows highlight instances of the markers. Credit: Alana Down Syndrome Center at MIT Studies by a growing…
, 2025-04-26 17:20:00 Salutegenic traits, like immune resilience, provide protection against pathogenic factors. Credit: UT Health San Antonio What if, rather than focusing solely on the drivers of disease (pathogenesis), we also explored the factors sustaining our health—the concept of salutogenesis (derived from Salus (health) in Roman mythology)? The idea of salutogenesis through immune resilience,…