Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later. If you continue to have…
Non-enzymatic production of diindoles. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-46559-3 Researchers at the University of Toronto have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues. This can be achieved by binding the compounds to an important, but poorly understood, nuclear receptor. The gut…
TOPLINE: iGlarLixi, a fixed-ratio combination of insulin glargine and the glucagon-like peptide-1 receptor agonist (GLP-1 RA) lixisenatide, improves glycemic control, with a low rate of hypoglycemia, in adults with inadequately controlled type 2 diabetes (T2D). METHODOLOGY: The 2022 Consensus Statement from the American Diabetes Association/European Association for the Study of Diabetes suggests that a fixed-ratio…
Hospitals’ operating margins and patient volumes dropped slightly in March, according to a new report from Kaufman Hall. Hospitals’ single-month operating margin index closed out March at 3.4% — a small dip from February’s 3.6%. It’s also worth noting that March ended with a year-to-date operating margin index of 3.9% — which is still significantly…
Therapist burnout negatively affected the delivery of trauma-focused psychotherapies (TFPs) to patients with posttraumatic stress disorder (PTSD), according to study results published in JAMA Network Open. Clinicians who experience burnout have previously reported that their symptoms affect the quality of care they deliver, their communication with patients, and the likelihood of making a medical error….
Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later. If you continue to have…
Vivien Dugan isn’t getting much sleep these days. The director of the influenza division at the Centers for Disease Control and Prevention, Dugan is leading the team of CDC scientists that is working with partners — in the U.S. Department of Agriculture, the Food and Drug Administration, and state and local health departments — to respond…
Credit: Pixabay/CC0 Public Domain Neuroblastoma is a common pediatric cancer that originates in developing nerve cells outside the brain. While increasingly intensive treatments have improved the survival of patients with high-risk neuroblastoma, currently more than 40% of patients do not survive. New research from the University of Chicago shows the potential for a promising new…
Expanding eligibility criteria is a strategy for improving the inclusion of traditionally underrepresented populations in clinical trials, according to a study. The results were published in NEJM Evidence by Maneet Kaur, PhD, epidemiologist and senior scientist at Flatiron Health, New York, and colleagues. Flatiron Health is an independent member company of the Roche group and…
It’s not uncommon for a patient, when searching their insurer’s provider directory, to find listings for physicians who are no longer practicing and no longer in-network, as well as inaccurate addresses, phone numbers, and websites. These phantom entries create “ghost networks” in health insurance. For more than a year ghost networks have made headlines as…
Philips received a warning letter from the FDA in February, which the Agency posted on Tuesday, stating that an inspection of the tech giant’s manufacturing facility in Suzhou, China, that makes CT and ultrasonography systems revealed it was not in compliance with the Quality System Regulation’s good manufacturing requirements. The FDA said an inspection of…
Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later. If you continue to have…
Amgen’s comments Thursday that it’s “very encouraged” by interim Phase 2 data for its obesity drug have quickly sparked immense investor interest in what could be a potential contender with Novo Nordisk’s Wegovy and Eli Lilly’s Zepbound. The injectable drug MariTide, designed to be given monthly, could be a more attractive option than Wegovy and…
UChicago Pritzker School of Molecular Engineering PhD candidate Anna Slezak is first author on recent paper on developing in-situ cancer vaccines could make immunotherapies more effective in the blood cancer acute myeloid leukemia and other blood cancers. Credit: Ryne Montoya Acute myeloid leukemia (AML) is a type of blood cancer that forms in the soft…
In a recent study published in The Lancet Digital Health, a group of researchers analyzed severe coronavirus disease 2019 (COVID-19) outcomes in patients with immune-mediated inflammatory diseases (IMIDs), focusing on the effects of medications, comorbidities, and vaccination status during different pandemic phases. Study: Machine learning to understand risks for severe COVID-19 outcomes: a retrospective cohort study…
May 3, 2024 – There are plenty of reasons to exercise, but some are more motivating than others. Perhaps the sexiest motivator – and the one people tend to go with, especially with warm weather around the corner – is to build the “beach body.” The problem: Setting big expectations for weight loss can position…
TOPLINE: Researchers have identified specific circulating microRNAs (miRNAs) in blood samples that can identify individuals at high risk of developing pancreatic cancer within 5 years, potentially improving early detection and outcomes. METHODOLOGY: Early detection of pancreatic cancer could improve patient prognosis, but clinically viable biomarkers are lacking. In a two-stage study, researchers screened and validated…
Amgen aims to challenge the Novo Nordisk and Eli Lilly duopoly in the market for injectable obesity medications, and the company is now preparing for Phase 3 testing of an injectable drug candidate that would introduce new competition. While executives are not yet sharing specific details of the clinical data that support these plans, Amgen’s…
AI-enabled protein design company Profluent has leveraged artificial intelligence to design an open-source gene editor called OpenCRISPR-1, demonstrating the technology can be used to create molecules with the power to edit human DNA. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology, developed more than a decade ago, allows scientists to modify DNA sequences within living…
Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later. If you continue to have…
The Warburg effect and metabolic rewiring. Credit: Cancer Biology & Medicine Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues for cancer treatments that target cellular metabolism. A century after Otto Warburg first described the phenomenon where cancer…
Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning! A crowdsourced Readout today, to be sure, with contributions from STAT’s Jason Mast, Elaine Chen, and Jonathan Wosen. We get into earnings from Novo Nordisk, Amgen, and Illumina, and see…
Do you ever struggle to hear conversations in noisy environments, or miss the chirping of birds on a walk? If so, Bluetooth hearing aids might be the solution you’ve been looking for. Bluetooth hearing aids have revolutionized the way individuals with hearing loss experience the world around them. By seamlessly connecting to smartphones, televisions, and…
Chronic spontaneous urticaria (CSU) can make you feel itchy and uncomfortable. It causes hives that come and go unexpectedly. You probably wonder why you get them and what to do about them.There’s no clear cause of chronic spontaneous urticaria, or chronic hives, but you and your doctor can manage it.“When I diagnose a patient with…
A dietary intervention involving plant-based food can help people with medical conditions, including liver disease and kidney disorders. But, for people who are used to eating meat all through their lives, making a drastic dietary change and sticking to it can be difficult.Here’s some good news: going meatless for just one meal a day could…
Bisoprolol safe and effective for treating chronic obstructive pulmonary disease: Study We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok Source link
Sibling death in childhood tied to increased risk of early-onset cardiovascular disease: JAMA We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok Source link
High serum Vitamin D levels significantly linked to protection of caries development in children, reveals study We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok Source link
Omega-6 fatty acid arachidonic acid may reduce risk of bipolar disorder, finds study We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok Source link
Protein and anti-inflammatory diet may help against cognitive decline: Study We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok Source link
Omega-6 fatty acid may lower bipolar risk, finds study We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok Source link
Researchers at the National Cancer Institute have developed an AI tool, PERCEPTION, that predicts patient responses to cancer treatment drugs using individual tumor cells. This approach provides better resolution data by utilizing single-cell RNA sequencing. The tool showed promise in clinical trials for myeloma and breast cancer by ranking drug combinations based on individual tumor…
Medical providers are still struggling after a cyberattack on a UnitedHealth Group subsidiary disrupted payments. The digital network affected processes a significant number of U.S. patient records. Providers are facing difficulties in receiving payments and managing billing without the electronic remittance information. The cyberattack has cost UnitedHealth $870 million with a total expected cost of…
Presenters at the ACP’s annual meeting discussed a new over-the-counter birth control option, norgestrel 0.075 mg (Opill), which is less effective than other options but important for women without health insurance. The presentation highlighted the importance of counseling patients on the pill’s history, side effects, and effectiveness, as well as the need to continue using…
Social media is now being seen as a more trusted source of information than physicians when it comes to weight loss medicines. People are making decisions based on posts by friends and influencers, sometimes even skipping consulting with a doctor. Biocon is developing its own version of the weight loss drug Wegovy and plans to…
Zaid Al-Najjar, the medical director of NHS Practitioner Health, emphasizes the importance of tailored mental health support for healthcare workers due to the unique demands of their profession. The success of NHS Practitioner Health, which started as a pilot program for doctors and dentists, highlights the increasing need for mental health support in the healthcare…
Tumor deposits (TDs) are clusters of tumor cells found in adipose and fibrous tissues near the primary tumor in various cancers, including colorectal and gastric cancer. They lack lymphoid structures and are not directly linked to the primary tumor. The 8th edition of TNM staging defines TDs as tumor cell deposits without identifiable vascular or…
Researchers developed the TORCH deep-learning approach to differentiate tumor origins using cytological histology pictures from over 57,000 patients with hydrothorax and ascites. The AI model showed high accuracy in predicting cancer origin compared to pathologists. TORCH improved junior pathologists’ diagnostic abilities and guided treatment choices, leading to better overall survival rates in patients. The model…
Buccal patches stuck to the inside of the mouth offer a quicker and potentially side effect-free way to deliver drugs, especially for those who struggle with swallowing pills or insulin injections. Buccal films and patches are developing as innovative methods of drug administration, providing benefits such as rapid onset of action, avoidance of gastrointestinal side…
Better communication between primary care clinicians and hospice providers can reduce the number of denied Medicare approvals for end-of-life treatment. Dr. Tyler Haussler conducted a study showing that poor documentation by physicians often leads to denials by CMS. Having a face-to-face conversation between the referring physician and hospice medical director improved the quality of documentation…
Korean sunscreens are revolutionizing sun care by offering innovative formulas that go beyond basic sunblock to provide multiple skincare benefits. These sunscreens have cutting-edge formulations, lightweight textures, and high levels of sun protection, making them a pleasure to wear and incorporate into your daily routine. Factors to consider when choosing a Korean sunscreen include broad-spectrum…
A recent study explores the use of non-thermal atmospheric-pressure plasma as a novel approach for treating bone fractures. This method shows promise in promoting bone healing and regeneration. The study highlights the potential benefits of using this technique in the treatment of fractures, offering an alternative to traditional methods. Researchers are continuing to investigate the…
Ilant Health, a virtual obesity management company, extended its seed funding round from $3 million to $5.5 million. Based in New York City, the company provides value-based care to employers and government payers nationwide. They match patients to personalized obesity treatment options such as intensive behavioral therapy, pharmacotherapy, and bariatric surgery. The funding includes participation…
In a special ceremony, renowned immunologist Dr. Anthony Fauci was awarded an honorary fellowship by the UCD School of Medicine and received the Fulbright Ireland Public Service Award for his outstanding contributions to public service. Dr. Fauci, who served as director of the U.S. National Institute of Allergy and Infectious Diseases, has been a key…
Chinese Hospital in San Francisco, located in Chinatown, faces financial challenges common in underserved areas. Many patients are elderly with limited incomes and rely on Medicare and Medi-Cal. The hospital receives lower reimbursement rates due to a federal rule and struggles with high costs. Despite this, it has strong community support and partnerships. Fundraising efforts…
The FDA has approved the subcutaneous administration of Takeda Pharmaceuticals’ Entyvio for maintenance therapy in adult patients with moderate-to-severe Crohn’s disease after induction therapy via IV administration. The approval was based on the results of a phase 3 clinical trial, VISIBLE 2, which showed that patients who received SC vedolizumab achieved higher rates of clinical…
Share your new hires, promotions, and job changes with us so we can share them with others. This week, Athira Pharma hired Javier San Martin as chief medical officer, previously of Arrowhead Pharmaceuticals. Don’t forget to take a break from work to keep things interesting! Visit STAT+ for the full story. Source link
Health analysts are calling on UK ministers to address the severe shortages of medicines that have become the “new normal” since Brexit. The Nuffield Trust has warned that global supply problems have worsened shortages of essential drugs like antibiotics and epilepsy treatments. The UK risks being left behind in addressing these issues outside the EU….
A team of cancer researchers has developed an AI model that can trace the origins of metastatic cancer cells in the body, improving outcomes for patients. In a study published in Nature Medicine, the team trained the AI with images of cancer cells from patients and found it to be 83% accurate in identifying the…
Researchers developed the MONET foundation model to connect medical images to text based on medically relevant ideas, aiding in medical AI development. They collected over 100,000 dermatology image-text pairs to train MONET to identify various concepts in dermatological images. MONET’s concept annotation capabilities were evaluated by comparing its performance to other models and used for…