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Sen. Collins slams NIH research cuts, urges funding be restored

John Wilkerson , 2025-04-30 14:32:00 WASHINGTON — Sen. Susan Collins (Maine), the Republican chair of the Senate Appropriations Committee, rebuked the Trump administration for cutting federal biomedical research funding, cancelling grants, and laying off federal health department employees, and said the changes must be reversed. “Proposed funding cuts, the firing of essential federal scientists,  and…

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Vapourtec video showcases fully automated peptide synthesis

, 2025-04-30 13:22:00 A recent video produced by Vapourtec highlights the patented automatic Variable Bed Flow Reactor (VBFR) demonstrating fully automated solid phase peptide synthesis. Image Credit: Vapourtec The process begins with swelling Tentagel S resin in DMF, preheating and Fmoc deprotection using 20% Piperidine in DMF. A reduction in resin volume marks this deprotection step, tracked on the…

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Hypoxemia Rare in Early Trauma Care

, 2025-04-30 13:05:00 TOPLINE: Only 5% of patients with trauma experienced significant hypoxemia within the first 8 hours of care, with no difference observed between restrictive and liberal oxygen strategies. METHODOLOGY: This substudy of the randomized TRAUMOX2 trial included 60 adults with trauma injury (median age, 49 years; 75% men) who were randomly assigned to…

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Trump restores Title X funding for two anti-abortion states — while wiping it out elsewhere

, 2025-04-30 10:55:00 The Trump administration quietly restored federal family planning money to Tennessee and Oklahoma, despite court rulings that the states weren’t entitled to funds because they refused to provide women information about terminating pregnancies or abortion referrals on request. The decision by the Department of Health and Human Services to restore millions of…

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New Fecal Product Expected to Enhance Microbiome Research

, 2025-04-30 12:07:00 The US National Institute of Standards and Technology (NIST) has developed precisely measured human fecal material to foster a new era in gut microbiome research.  According to the American Gastroenterological Association’s Center for Gut Microbiome Research & Education, this critical resource will help advance the utility and reproducibility of microbiome-based diagnostics —…

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Parallel activity in orbitofrontal cortex and hippocampus shapes cognitive maps and schemas, study suggests

, 2025-04-30 10:30:00 Task design, histology and behavior. Credit: Zong et al. (Nature Neuroscience, 2025). As humans and other animals navigate their surroundings and experience different things, their brain creates so-called cognitive maps, which are internal representations of environments or tasks. These mental maps are eventually generalized into schemas, frameworks that organize information acquired through…

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Curcumin’s role in combating obesity and neuroinflammation

, 2025-04-30 08:30:00 A new study highlights the antioxidant and anti-inflammatory effects of curcumin, suggesting its potential as a therapeutic agent for metabolic disorders and brain health. Study: Curcumin Modulation of the Gut–Brain Axis for Neuroinflammation and Metabolic Disorders Prevention and Treatment. Image Credit: New Africa / Shutterstock.com A recent Nutrients study explores the medicinal role…

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Metabolic Syndrome in Midlife Tied to Early-Onset Dementia

, 2025-04-30 09:44:00 TOPLINE: Metabolic syndrome was associated with a 24% increased risk for young-onset dementia, defined as dementia before the age of 65 years, with stronger associations found in women vs men, younger vs older adults, and individuals with vs without depression, a new study showed. METHODOLOGY: This nationwide population-based cohort study included data…

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Trump Restores Title X Funding for Two Anti-Abortion States — While Wiping It Out Elsewhere

Rachana Pradhan , 2025-04-30 09:00:00 The Trump administration quietly restored federal family planning money to Tennessee and Oklahoma, despite court rulings that the states weren’t entitled to funds because they refused to provide women information about terminating pregnancies or abortion referrals on request. The decision by the Department of Health and Human Services to restore…

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AHA stands together with Arkansas and against the soda industry to reduce sugary drink consumption

, 2025-04-30 08:34:00 Credit: CC0 Public Domain The American Heart Association, committed to changing the future of health for everyone, everywhere, is standing with Arkansas health officials in their efforts to reduce sugary drink consumption in the face of fierce opposition by the soda industry. The Association has submitted written comments in support of the…

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New antiviral compounds show broad protection against COVID-19 variants

, 2025-04-30 08:05:00 AVI-4773 and related MPro inhibitors outperform existing treatments like nirmatrelvir in preclinical studies, offering a promising path toward pan-coronavirus therapies. Study: Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy. Image Credit: H_Ko / Shutterstock.com Since the start of the coronavirus disease 2019 (COVID-19) pandemic, numerous novel antiviral…

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New Tool Predicts Vasectomy Regret Before Surgery

, 2025-04-30 08:00:00 Vasectomy, an increasingly popular method of male contraception, is appealing because of its simplicity, reliability, and effectiveness. However, its irreversible nature can sometimes lead to regret among patients. To address this, European experts, including Belgian teams, have developed a tool to predict potential regret following the procedure. Performed under local anesthesia, vasectomy…

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New Tool Predicts Vasectomy Regret Before Surgery

, 2025-04-30 08:00:00 Vasectomy, an increasingly popular method of male contraception, is appealing because of its simplicity, reliability, and effectiveness. However, its irreversible nature can sometimes lead to regret among patients. To address this, European experts, including Belgian teams, have developed a tool to predict potential regret following the procedure. Performed under local anesthesia, vasectomy…

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FDA, Makary on vaccines, HPV shot, trans health

Elizabeth Cooney , 2025-04-29 12:00:00 Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here. Good morning. Liz Cooney here taking a turn with the newsletter while Theresa’s out exploring the world.  Today is officially the 100th day of the second Trump administration, a tenure marked by…

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Higher cigarette taxes may improve childhood survival

, 2025-04-29 22:30:00 Credit: Unsplash/CC0 Public Domain A higher tax on cigarettes in low and middle-income countries (LMICs) can help to reduce child mortality, especially among the poorest children, a new study led by researchers at Karolinska Institutet and published in The Lancet Public Health suggests. The paper is titled “Cigarette taxation and socioeconomic inequalities…

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AI tools could prevent maternal heart-related deaths

, 2025-04-30 02:28:00 Every year, some mothers die after giving birth due to heart problems, and many of these deaths could be prevented. The ability to screen for heart weakness before pregnancy could play a crucial role in identifying women who may need additional care to improve pregnancy outcomes. Mayo Clinic researchers, led by Anja Kinaszczuk, D.O., and Demilade…

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A Safer Sedation for Atrial Fibrillation Ablation?

, 2025-04-30 06:32:00 TOPLINE: The combination of remimazolam and ketamine for deep analgosedation during pulsed-field ablation for atrial fibrillation was associated with fewer adverse events than propofol-based methods, with the regimen significantly reducing hypoxemia and hypotension. METHODOLOGY: Czech researchers conducted a prospective randomized controlled trial involving 127 patients (mean age, 62.9 years; 35.1% women) with…

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Readout Newsletter: Abeona, Pfizer, Regeneron, AstraZeneca

Elaine Chen , 2025-04-29 13:58:00 Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning, we’ve got a bunch of news this morning about GLP-1 drugs,  compounding, and biotechs’ interactions with the FDA. Let’s get into it. The need-to-know this morning Abeona…

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Parents with alcohol-related diagnoses are twice as likely to maltreat children, researchers find

, 2025-04-30 04:10:00 Credit: Unsplash/CC0 Public Domain A new systematic review has found that parents and other child caregivers who have alcohol-related diagnoses are twice as likely to maltreat children in their care than parents and caregivers with no alcohol-related diagnoses. The review is published in Addiction. “Alcohol-related diagnoses” included alcohol-related hospitalization, alcohol-related service use,…

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Study uncovers why anxiety and depression lead to low self-belief

, 2025-04-30 02:31:00 Researchers at UCL have uncovered why individuals who experience anxiety and depression often struggle with persistent low self-belief in their abilities. A new study, published in Nature Communications, examined two large groups of people (230 and 278 participants) to measure their “confidence” when doing individual jobs and their “self-belief” when judging their overall…

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A Resident’s Guide to Finding Your First Position

, 2025-04-29 11:51:00 Elisa Zenni, MD, recalls the process of completing her fellowship training in Boston, while at the same time, trying to land her first job in academic pediatric medicine. The Navy had stationed her husband, also a doctor, in Bay Area, California. Some professional couples are willing to live apart, but Zenni and…

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ADHD and anxiety show different patterns in boys and girls

, 2025-04-30 02:35:00 ADHD can exacerbate anxiety, and anxiety can exacerbate ADHD. Girls are particularly vulnerable to developing anxiety disorders, but researchers have recently discovered something that may help slow down – or prevent – the development of these types of disorders. Researchers at the Norwegian University of Science and Technology (NTNU) have found new…

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New Study Says Measles Could Become Endemic: 3 Key Takeaways

, 2025-04-30 02:59:00 Back in 2000, health experts declared measles had been eliminated from the United States thanks to an ambitious measles-mumps-rubella (MMR) vaccination program for children. But as vaccination rates decline, measles is making a troubling comeback. As of Friday, the CDC says that nearly 900 measles cases have been reported in at least…

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Exercise helps mitigate cancer treatment side effects

, 2025-04-30 02:17:00 Exercise can counter the detrimental effects of cancer treatment, such as heart and nerve damage and brain fog, suggests an overarching review of the existing pooled data analyses of the most recent research, published online in the British Journal of Sports Medicine. Exercise also seems to boost psychological wellbeing and overall quality of…

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Polyhydramnios Linked to Higher Postpartum Haemorrhage Risk

, 2025-04-29 12:00:00 TOPLINE: Women with polyhydramnios faced a higher risk for postpartum haemorrhage (PPH), with caesarean section delivery and foetal macrosomia serving as independent risk factors and prophylactic oxytocin use offering protection. METHODOLOGY: This retrospective single-centre study (2015-2022) aimed to identify risk factors for PPH among pregnancies with polyhydramnios, focusing on uterine overdistension and…

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Hospitals Leaders Share How They’re Balancing Finance, Innovation and Patient Care

Katie Adams , 2025-04-29 22:38:00 Amid market shifts and shallower pockets, health system leaders are restrategizing. Hospitals across the country are juggling new and ongoing financial pressures, increasing digital health initiatives and the need to provide high-quality care.  On Monday during a session at the symplr Healthcare Operations Summit in Chicago, hospital leaders discussed how…

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