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New algorithms can help GPs predict which of their patients have undiagnosed cancer

, 2025-05-07 09:00:00 Credit: Pixabay/CC0 Public Domain Two new advanced predictive algorithms use information about a person’s health conditions and simple blood tests to accurately predict a patient’s chances of having a currently undiagnosed cancer, including hard-to-diagnose liver and oral cancers. The new models could revolutionize how cancer is detected in primary care, and make…

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New consensus on clear aligner treatment aims to improve orthodontic outcomes

, 2025-05-07 06:29:00 Malocclusion affects nearly half of the global population, impacting oral function and aesthetics. Clear aligners have gained popularity due to their discreet appearance and ease of use, but their effectiveness varies depending on the type of tooth movement required. Unlike fixed appliances, clear aligners rely on elastic forces, which can complicate complex…

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Do GLP-1s Lower CRC Risk in Patients With Obesity and T2D?

, 2025-05-07 07:53:00 SAN DIEGO — Patients with obesity and type 2 diabetes treated with glucagon-like peptide 1 (GLP-1) receptor agonists had significantly reduced rates for colorectal cancer (CRC) risk and associated mortality compared with those undergoing bariatric surgery, new research showed. CRC risk was also lower for patients taking GLP-1s than the general population….

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More than 1.6 million drivers opt-in to organ donation

Michael McHale , 2025-05-07 07:30:00 New Human Tissue Act will see establishment of ‘opt-out’ register for organ donation More than 1.6 million drivers in Ireland have registered as potential organ donors, according to new figures released to mark Organ Donation Awareness Week. Data from the Road Safety Authority shows that, as of last Friday, 1,609,351…

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During aging, people with Down syndrome may face a higher risk of cardiovascular disease

, 2025-05-07 07:10:00 Credit: Unsplash/CC0 Public Domain Because life expectancy for individuals with Down syndrome has increased dramatically, investigators assessed the risk of age-related cardiovascular diseases in this population. As reported in the Journal of Internal Medicine, the researchers found increased risks of various cardiovascular diseases compared with the general population. In the study, 5,155…

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Gastrointestinal cancer patterns vary across diverse Asian and Pacific Islander populations

, 2025-05-07 06:45:00 The incidence of gastrointestinal cancers varies across Asian American, Native Hawaiian and other Pacific Islander communities, according to a study published March 15 in the journal Gastro Hep Advances.  When combined, Asian American, Native Hawaiian and other Pacific Islander communities compose the fastest-growing group in the United States. They accounted for 6.2% of the…

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Limited Awareness and Uptake Gaps of RSV Vaccine in Seniors

, 2025-05-07 06:39:00 TOPLINE: Only one tenth of hospitalized adults aged 60 years or older received the respiratory syncytial virus (RSV) vaccine during its first season. Sociodemographic differences were observed, with higher vaccine uptake among those aged 75 years or older, those with pulmonary disease, and those with an immunocompromised status. METHODOLOGY: In this cross-sectional…

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Precision medicine approach improves treatment for soft tissue sarcomas

, 2025-05-07 05:58:00 A study conducted by researchers from the Agency for Science, Technology and Research (A*STAR), National Cancer Centre Singapore (NCCS) and National University of Singapore (NUS), in collaboration with biotech company, KYAN Technologies, has demonstrated that a precision medicine approach improves treatment selection for patients with soft tissue sarcomas (STS) in a clinical…

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Limited Access to Cardioprotective T2D Meds in Medicaid

, 2025-05-07 05:15:00 TOPLINE: Medicaid enrollees with type 2 diabetes (T2D) continue to face restricted access to newer cardioprotective diabetes medications — sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 receptor agonists (GLP-1 RAs) — despite recommendations as first-line treatment those also at risk for cardiovascular disease. METHODOLOGY: For adults with T2D, studies suggest…

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Waters integrates Multi-Angle Light Scattering Detectors with empower software for improved biologics quality control and simplified regulatory compliance

, 2025-05-07 04:29:00 Waters Corporation today announced that its Empower™ Software now supports biologics data acquisition and quality control (QC) analysis from Multi-Angle Light Scattering (MALS) and differential Refractive Index (RI) instruments in its Wyatt Technology™ Portfolio. This integration expands the scope of critical quality attributes that a biopharmaceutical laboratory can manage using Empower Software. Additionally,…

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Trump Team’s $500M Bet on Old Vaccine Tech Baffles Experts

, 2025-05-07 04:42:00 The Trump administration’s unprecedented $500 million grant for a broadly protective flu shot has confounded vaccine and pandemic preparedness experts, who said the project was in early stages, relied on old technology, and was just one of more than 200 such efforts. Health and Human Services Secretary Robert F. Kennedy Jr. shifted…

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NIH Clinical Center, wildfire deaths, etc.

Theresa Gaffney , 2025-05-06 12:47:00 Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here. Good morning, I’m back! It seems like there was a lot of news while I was away …. drop me a line at [email protected] to let me know the biggest stories I…

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Nanoplastics are all around (and inside) us

, 2025-05-06 20:36:00 Credit: Unsplash/CC0 Public Domain Each year, more than 400 million metric tons of plastic are produced globally from petrochemicals derived from fossil fuels. Only 9% of this plastic is recycled and 19% is incinerated; 72% goes to landfills, other dumpsites or ends up in our environment. These plastics degrade into smaller and…

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NCCN hosts Oncology Policy Summit to bridge primary and cancer care

, 2025-05-07 02:58:00 The National Comprehensive Cancer Network® (NCCN®) hosted an Oncology Policy Summit in Washington, D.C., today, focused on improving care coordination between primary care and oncology providers. The program featured a diverse group of patients, advocates, practitioners, and policy makers weighing in on how to improve cancer prevention, detection, treatment, and long-term survival….

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Hormonal IUDs Not Linked to Melasma Risk

, 2025-05-07 03:01:00 TOPLINE: Hormonal intrauterine devices (IUDs), unlike oral contraceptives, were not linked with an increased risk for melasma in women with menorrhagia, this study found. METHODOLOGY: Researchers analyzed data from the TriNetX Research Network spanning 95 healthcare organizations from 2001 to 2024, identifying patients with menorrhagia aged 18-52 years who received hormonal contraceptives….

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What Does HHS’ Restructuring Mean for Interoperability In Healthcare?

Katie Adams , 2025-05-07 00:01:00 Healthcare leaders are continuing to express their concerns about the changes that President Donald Trump’s administration is making to HHS. Just this week, 20 state attorneys general sued the administration, saying that the department’s restructuring plan and resulting layoffs are unconstitutional and dangerous for public safety. Experts say the fallout…

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Digital Collaborative Care Model Improves IBS Symptoms

, 2025-05-06 11:42:00 SAN DIEGO — An artificial intelligence (AI)–enhanced digital collaborative care model led to rapid, clinically significant, and sustained symptom relief for patients with irritable bowel syndrome (IBS) seen at Cleveland Clinic, Cleveland, an observational study found. Symptom tracking at 4-week intervals showed that “almost everybody got better” regardless of IBS subtype, with…

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Trump asks judge to toss suit restricting mifepristone access

Associated Press , 2025-05-06 13:27:00 WASHINGTON — The Trump administration has asked a judge to toss out a lawsuit from three Republican-led states seeking to cut off telehealth access to the abortion medication mifepristone. Justice Department attorneys on Monday stayed the legal course charted by the Biden administration, though they didn’t directly weigh in on the…

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Varicose veins increase your risk of dementia, study finds

, 2025-05-06 23:59:00 A nationwide Korean study finds a surprising link between varicose veins and dementia, and suggests that treating the veins could help prevent vascular brain damage. Study: Association between varicose veins and the occurrence of dementia: A nationwide population-based cohort study. Image Credit: New Africa / Shutterstock.com A recent PLOS One study explores the…

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AIDS-Related Illnesses Lead Global HIV Hospitalizations

, 2025-05-06 11:48:00 TOPLINE: AIDS-related illnesses continued to be the leading cause of hospitalization, accounting for 42% of the admissions, with tuberculosis being the most frequent illness. This pattern was consistent across all age groups. METHODOLOGY: Researchers conducted an updated meta-analysis of 110 studies to determine the causes of hospitalizations and the risk for in-hospital…

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Vinay Prasad to run key FDA division that oversees vaccines

Lizzy Lawrence, Jason Mast, and Matthew Herper , 2025-05-06 16:50:00 WASHINGTON — Vinay Prasad, an academic and fierce critic of the medical mainstream, will be the next director of the Food and Drug Administration center that oversees the regulation of vaccines, gene therapies, and the blood supply.  Prasad, previously an epidemiology professor at the University of…

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Physician-led online nutrition intervention program is successful at improving health for patients with type 2 diabetes

, 2025-05-06 20:38:00 Credit: Tima Miroshnichenko from Pexels An online physician-led plant-based nutrition intervention program for patients with type 2 diabetes is practical, cost-effective, and successful at improving patient health, finds a new study by the Physicians Committee for Responsible Medicine published in the American Journal of Lifestyle Medicine. The program led to reductions in…

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Rethinking the social side of problem drinking

, 2025-05-06 12:12:00 When picturing a “typical” alcoholic, people tend to imagine a person drinking at home alone. But that focus overlooks the social origins of many serious alcohol problems, say the authors of a new review paper in the journal Current Directions in Psychological Science. “Evidence for the centrality of social motives in problem…

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Oura Ring now syncs with Dexcom’s Stelo CGM

, 2025-05-06 21:11:00 Glucose monitoring specialist Dexcom is expanding its partnership with health-tracking ring maker Oura to provide Stelo users and ring wearers with metabolic health features, including meal insights and glucose data.  Stelo provides individuals 18 and up who do not require insulin with round-the-clock glucose readings and delivers personalized insights into glucose health,…

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Researchers recommend new standard of care for families with hereditary neuroblastoma linked to ALK mutation

, 2025-05-06 21:23:00 Radiographic findings. (A) Coronal T2-weighted image shows a small, ovoid right adrenal mass (white arrow) and larger, triangular left adrenal mass (black arrow) with heterogeneity and higher T2 signal intensity than the right adrenal mass. (B) Coronal T2 HASTE fetal MRI image shows a fetus with normal adrenal glands. (C) Two months…

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Heart Health Worsened in Pts With Chronic Hypoparathyroidism

, 2025-05-06 12:00:00 TOPLINE: Patients with chronic hypoparathyroidism faced a significantly higher risk for cardiovascular diseases and mortality from cardiovascular causes than control individuals without the condition, with the effect being particularly prominent among women. METHODOLOGY: Researchers conducted this study by merging data from population-based registries in Sweden to assess the risk for cardiovascular diseases…

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