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UK Maternal Mortality Rates Reach Two-Decade High

Maternal mortality rates in the UK have reached levels not seen since 2003-2005, according to a study by MBRRACE-UK. The maternal death rate in 2020-2022 was 13.41 deaths per 100,000 maternities, compared to 8.79 in 2017-2019. Thrombosis and thromboembolism were the leading causes of maternal death, followed by COVID-19, suicide, and sepsis. The report also…

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Noom, Liviniti partner on GLP-1 Companion platform

Noom, a digital weight loss company, has partnered with a pharmacy benefit manager, Liviniti, to offer a digital GLP-1 Companion for chronic weight conditions to plan sponsors and their employees. The GLP-1 Companion integrates with PBM processes, offering nutrition guidance and fitness-focused lessons to help those taking GLP-1 medications. Noom aims to support lasting habits…

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Cytokinetics and Novartis’ starcrossed tale

If you are interested in staying up to date on the latest developments in the biotech industry, you can sign up for the STAT biotech newsletter in your inbox. This week’s newsletter includes topics such as the aftermath of the JPM conference, FDA review of GLP-1 drugs, Novartis’ decision not to acquire Cytokinetics, and a…

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William Stanley Monkhouse | The BMJ

Reverend Stanley Monkhouse had a diverse career as an organist, doctor, teacher, Anglican priest, and blogger. He was a medical undergraduate at Queens’ College, Cambridge, where his interest in anatomy and embryology began. In his third year, he studied art history, suggesting a non-traditional career path. Proud of his Cumbrian roots, he pursued various passions…

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Stroke Risk in Young and Middle-Aged Adults

On a hot day in Nashville, writer Sekou Writes had a hemorrhagic stroke. Research shows strokes are rising in young adults and middle-aged individuals, due to lifestyle factors such as high blood pressure, diabetes, smoking, and obesity. Sedentary lifestyle during the pandemic may have also contributed to this increase. Writes, who had been on a…

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CMS Okays Payment for Novel AI Prostate Test

Medicare will now cover an AI-based test for prostate cancer that predicts which men will benefit from androgen deprivation therapy. The Centers for Medicare & Medicare Services approved the payment rate for ArteraAI as a clinical diagnostic test. The test improves risk stratification and personalizes treatment. It combines a patient’s clinical and pathologic information into…

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ED interrogates Jharkhand IAS officer’s wife

An Indian Administrative Service (IAS) officer’s wife from Jharkhand is being interrogated by the Enforcement Directorate (ED) in connection with the Berlin Hospital Land case. This case involves alleged irregularities in the acquisition of land in Germany for a hospital project. The ED is investigating potential financial misconduct and illegal transactions related to the case….

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Medical Innovation Must Shift Focus From Common Problems to Unsolvable Ones

The economics of healthcare have historically driven innovation in common conditions with high patient volumes, such as cardiovascular disease. However, as technology grows more sophisticated, the focus in medical discovery is shifting towards solving previously considered impossible problems. Advancements in surgical technology are redefining the boundaries between possible and impossible, particularly in repairing microscopic anatomy…

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Polypharmacy project improves patient care

A cross-border project called iSIMPATYHY has led to improved patient safety by reducing adverse drug reactions. The project, which involved health services in Ireland, Northern Ireland, and Scotland, trained additional healthcare professionals in polypharmacy and medicines reviews. The project resulted in over 2,500 comprehensive medicines reviews by pharmacists in GP practices in border counties. As…

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Polycystic Ovary Syndrome Status Unrelated to Fertility Treatment Births

Fertility treatment-attributed births are similar among patients with and without polycystic ovary syndrome (PCOS) regardless of fertility treatment pathway. A study found that despite the variety of available treatment options, the effectiveness of different treatment pathways remains unclear. Patients with PCOS were more likely to start their treatment with ovulation induction and were less likely…

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Zeta Surgical mixed reality navigation gets FDA special 510(k) clearance

Zeta Surgical, a company specializing in surgical robotics and mixed reality, has obtained FDA special 510(k) clearance for its cranial navigation system for neurosurgery. The system offers real-time guidance with millimeter precision, eliminating the need for general anesthesia and rigid skull immobilization. The Special 510(k) clearance covers workflow and performance enhancements, such as streamlined navigation…

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Alex Azar’s Unusual Spin Through the Revolving Door

Former Health and Human Services secretary Alex Azar, who spent a decade with pharmaceutical giant Eli Lilly and Co, has now become the chairman of the board of a company trying to make prescription drug imports happen. The company, LifeScience Logistics, is managing Florida’s Canadian importation program and is being paid $39 million by the…

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Surgeon shares tips for incorporating botulinum toxins into ophthalmic practice

In a presentation at Hawaiian Eye/Retina 2024, Dr. Joely Kaufman discussed the differences between the five available botulinum toxins for treating glabellar muscle contraction. She advises starting with just one toxin to get used to it before incorporating others. She also highlighted five common glabellar contraction patterns and emphasized the importance of dosing based on…

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Arena BioWorks launches in Cambridge to speed drug discovery

A new biomedical institute called Arena BioWorks is being launched in Cambridge’s Kendall Square, with $500 million in private funding. The institute aims to shorten the time from research to life-saving medicines by combining drug discovery and company creation under one roof. This model challenges the traditional separation of academic research and venture-backed drug development….

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Akhil Chandra Biswas | The BMJ

Akhil Chandra Biswas, a consultant paediatrician, former international adviser to the Royal College of Physicians, and professor, has passed away after battling idiopathic pulmonary fibrosis. Known as Andy to colleagues and friends in the UK, Biswas was a dedicated scholar committed to paediatric care. Born in pre-independence India, he overcame significant challenges to complete his…

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Tapering of inhaled steroids feasible for asthma controlled with benralizumab

A study published in The Lancet found that patients with severe eosinophilic asthma controlled on bevacizumab can successfully taper their inhaled corticosteroids (ICS) without worsening asthma control. The study involved adults with severe eosinophilic asthma who tapered their high-dose ICS to a medium-dose, low-dose, and as-needed dose. The study found that 92 percent of patients…

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Learning to Live With Chronic Migraine

In the summer of 2005, Qasim Amin Nathari suffered memory loss while giving a sermon at a New Jersey mosque due to medication for severe migraines. He decided to openly address his condition with the congregation and has been met with understanding and support. Having experienced a hemiplegic migraine, he discussed a backup plan with…

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Europe Tightens Valproate Treatment Rules

The European Medicines Agency has recommended precautionary measures for the treatment of male patients with valproate after concerns about an increased risk of neurodevelopmental disorders in children fathered by men treated with the drug. The treatment should be started and supervised by a specialist and the potential risks explained to patients. Regular reviews of the…

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Red Cross Urges Action Amid Emergency Shortage

The American Red Cross has reported a critical blood shortage in the United States, with donations at an all-time low. This has resulted in a deficit of nearly 7,000 units of blood, impacting hospitals’ ability to meet the demand. This problem is compounded by the upcoming winter weather and the ongoing COVID-19 pandemic, which may…

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The Case for Asset Stewardship: How Healthcare Wastes Millions of Dollars on Endoscope Ownership

The use and ownership of endoscopes and other medical instruments in U.S. hospitals come with significant costs and challenges. These instruments are expensive to acquire and maintain, and hospitals often face hidden costs in service contracts and repair agreements. As a result, the healthcare industry is unnecessarily spending millions of dollars on these instruments. To…

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Report finds lack of resources available to adopt behavioural and cultural insights in public health

Ireland has scored highly in all five commitments to adopt behavioural and cultural insights (BCI) in public health, as outlined by the World Health Organisation. The WHO resolution aims to use BCI to combat major health issues, such as cancer, hypertension, vaccination coverage, antimicrobial resistance, and climate change. Ireland’s Chief Medical Officer, Prof Breda Smith,…

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Rezafungin May Provide Early Treatment Benefit in Candidemia, Invasive Candidiasis

A comparison of rezafungin and caspofungin for the treatment of candidemia and invasive candidiasis found that rezafungin may offer an early treatment benefit with its front-loaded dosing regimen. Study findings published in The Lancet Infectious Diseases showed that rezafungin was noninferior to caspofungin in terms of all-cause mortality and had higher rates of mycologic eradication….

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Ways to Lose Weight Without Diet or Exercise

There are unconventional ways to lose weight without traditional dieting or intense physical activity, such as mindful eating, getting sufficient sleep, stress management, and hydration/nutrition awareness. Mindful eating involves fully engaging in the dining experience and being deliberate in savoring the sensory aspects of meals, leading to a decrease in calorie consumption. Getting sufficient sleep…

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Paul Cassford Weaver | The BMJ

Paul Cassford Weaver was a university student involved in rowing and climbing. After completing surgical training in London, he did a fellowship at Massachusetts General Hospital in Boston. In 1976, he became a surgical oncologist consultant at Portsmouth Hospitals and also served as the director of surgery. Source link

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African women living with HIV have an effective option to prevent malaria during pregnancy, clinical trial finds

A clinical trial conducted by the Barcelona Institute for Global Health (ISGlobal) found that preventive treatment with DHA-PPQ is a safe and effective strategy to prevent malaria during pregnancy in women living with HIV. Pregnant women with HIV who were given DHA-PPQ had a significantly lower risk of developing clinical malaria throughout pregnancy and a…

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Are You Unwittingly Aiding the Rise of Superfungi?

Researchers have found that prescriptions for topical antifungal medications are being given out without proper consideration, potentially leading to microbial resistance. This indiscriminate use of these medications may pose a threat to their effectiveness in the future. The findings highlight the need for more cautious and targeted prescribing of topical antifungal treatments to prevent the…

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Expert Debunks Misconceptions About Blood Donation

January is National Blood Donor Month aimed at raising awareness about blood donation’s importance, especially as the U.S. faces an emergency shortage due to a 40% drop in donations over the past 20 years. Many myths and fears keep healthy potential donors away. Dr. Jessica Jacobson, director of Blood Bank and Transfusion Medicine at Bellevue…

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Manufacturing Issues Block Astellas From a First-in-Class Cancer Drug Approval

Astellas Pharma’s drug approval for zolbetuximab, a promising treatment for gastrointestinal cancer, has been delayed by the FDA due to manufacturing issues at a third-party facility. The FDA did not raise concerns about the drug’s safety or efficacy but cited unresolved deficiencies during the pre-license inspection. Zolbetuximab targets a specific protein found in stomach cells,…

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Why winter vaccination is important for healthcare workers

Ireland is experiencing high levels of influenza and Covid-19, with over 2,800 cases reported in the first week of 2024. The HSE is urging eligible individuals to get vaccinated. Dr. Alice Quinn from the National Immunisation Office emphasizes the importance of vaccination for healthcare workers. Vaccination reduces the risk of infection for workers and the…

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Key Factors of COVID-19 Vaccine Acceptance in People Experiencing Homelessness

A study published in BMC Infectious Diseases found that while COVID-19 vaccine acceptance rates have increased among people experiencing homelessness, targeted public health interventions are still needed to further address vaccine uptake in this vulnerable population. Researchers conducted a systematic review and meta-analysis of 29 studies to determine factors associated with vaccine acceptance and uptake….

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Beat Bladder the Blues: Strength, Beauty and Power

Urinary incontinence can be managed through various treatments beyond traditional methods. Lifestyle changes can help prevent and manage symptoms. For women in menopause, hormone replacement therapy, as well as antidepressants, may offer relief. The diversity of gut bacteria can also affect urinary incontinence. Pelvic floor exercises can provide some relief, particularly for postmenopausal women. Advanced…

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