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Cancer outcomes ‘at risk of going backwards’, clinicians warn

Twenty-one leading clinicians and academics have written an open letter to the Taoiseach urging the government to reverse its decision to not fund the National Cancer Strategy this year. The letter highlights the negative impact of underfunding on cancer outcomes, including delays in screenings, surgeries, and treatments. Ireland has the third-highest cancer mortality rate in…

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Kidney Failure Risk Equation May Improve Vascular Access Planning

Using the kidney failure risk equation (KFRE) alongside estimated glomerular filtration rate (eGFR) for vascular access planning may help more patients start hemodialysis with arteriovenous fistula or grafts at appropriate times. A study of 2581 adults found that creating a fistula or graft within 2 years of hemodialysis initiation was more likely in patients with…

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Neighborhood not associated with subjective cognitive decline in Black women

A study presented at the American Academy of Neurology annual meeting found that location of residence was not associated with subjective cognitive decline in Black women. The research analyzed data from the Black Women’s Health Study, including 20,768 individuals. The Area Deprivation Index, used to measure neighborhood disadvantage, did not show any significant differences in…

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Researchers find ethnic minorities are underrepresented in studies into multiple long-term health conditions

New research indicates that ethnic minorities are not adequately represented in studies on multiple long-term conditions (MLTCs), despite being more susceptible to these conditions. A systematic review published in the Journal of the Royal Society of Medicine highlighted a lack of reporting on ethnicity and underrepresentation of ethnic minority groups in intervention studies aimed at…

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Study finds low and high GI diets boost endurance performance over low-carb diets

A study was conducted on the effects of varying carbohydrate intake and glycemic index on endurance performance in men during a 10-week exercise and nutritional intervention. The study compared a low-carb high-fat (LCHF) diet, high-GI diet, and low-GI diet. The low-GI diet showed reduced energy intake, improved metabolic flexibility, and endurance performance. The LCHF diet…

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The Truth About Whole-Body Scans

Whole-body CT scans are becoming increasingly popular as a preventive health measure, but their effectiveness and safety are a matter of debate among medical experts. These scans use computed tomography to examine different parts of the body for early signs of abnormalities, but they are expensive and not typically covered by insurance. The radiation exposure…

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Tension, Other Headache Types Robustly Linked to Suicide

A large study found that headaches, including tension-type, migraine, and posttraumatic headache, are strongly linked to both attempted and completed suicide. Individuals with trigeminal and autonomic cephalalgias (TAC) had a four times higher risk of suicide attempt, while those with posttraumatic headache had double the risk of completed suicide compared to those with no headache….

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Addition of Metronidazole to Cefazolin Reduces Surgical Site Infections risk in Gynecologic Surgery, finds study

A study has found that adding metronidazole to cefazolin reduces the risk of surgical site infections in gynecologic surgery. By combining these two antibiotics, the study showed a decrease in postoperative infections. This finding may lead to improved surgical outcomes and reduced complications for patients undergoing gynecologic procedures. Source link

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AHIP, AMA, NAACOS Release Playbook for Value-Based Care

Three healthcare organizations, including AHIP, AMA, and NAACOS, have collaborated to release a playbook outlining best practices for value-based arrangements as the industry shifts away from fee-for-service models. The playbook focuses on improving patient experience, advancing population health, and reducing costs, with recommendations organized into seven domains. The goal is to help payers, physicians, hospitals,…

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IgA Nephropathy Prognosis Worse With Microangiopathy

The presence of microangiopathy in patients with immunoglobulin A nephropathy (IgAN) is associated with a worse prognosis, as shown in a study of 450 patients. Patients with microangiopathy had a significantly increased risk for kidney outcomes, including a decrease in estimated filtration rate, end-stage kidney disease, kidney transplantation, or death. The group with microangiopathy also…

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Public awareness campaign on risks of accessing weight loss surgery overseas is crucial

Surgeon Sala Abdalla warns about the risks of having surgery abroad, particularly in weight loss and cosmetic surgery. Patients are not adequately informed of the potential complications that can arise from medical procedures conducted outside their home country. Abdalla has personally treated multiple patients who experienced complications after undergoing surgery overseas. The rise of health…

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Intestinal neurons in infancy could explain wide-ranging gastrointestinal disorders in children

A new theory proposed by Wu Tsai Neuro Faculty Scholar Julia Kaltschmidt and MD/Ph.D. candidate Lori Dershowitz suggests that defects in the organization of gut neurons in infancy may be linked to pediatric gastrointestinal motility disorders. This theory, published in a Perspective article in the journal Cellular and Molecular Gastroenterology and Hepatology, highlights the importance…

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Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Antisense oligonucleotides (ASOs) are promising next-generation drugs that can block harmful messages from genes, potentially treating diseases like cancer. However, delivering ASOs into cancer cells has been a major challenge as the cells have gatekeeper molecules that prevent their entry. Researchers at Osaka University have developed a new compound called L687, which opens specific calcium…

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How New Ideas Are Changing Advanced Breast Cancer Research

Dr. Lisa Newman highlights reasons for hope for women with advanced breast cancer, including improving treatments and targeted therapies with fewer side effects. Research on circulating cancer cells and precision medicine is promising. However, African American women face higher death rates due to systemic racism affecting healthcare access and delays in diagnosis. More research is…

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First Long-Term Data on Atogepant for Migraine Prevention

An ongoing extension study supports the long-term safety and efficacy of the oral CGRP receptor antagonist atogepant in preventing chronic and episodic migraine. 70% of patients treated with atogepant achieved at least a 50% reduction in monthly migraine days at 13-16 weeks, maintained over 48 weeks. The study, reported at the American Academy of Neurology…

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Know All About Deadly Infection

A 37-year-old man in Hong Kong tested positive for the rare human B virus after being attacked by a wild monkey. The virus can lead to severe brain damage or death and can be transmitted through bites, scratches, or contact with saliva, feces, urine, or tissue from infected monkeys. Symptoms of infection include flu-like symptoms,…

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EConsent Workflows Must Evolve to Support Interoperability and Health Equity

A webinar on April 16 at 1pm ET will discuss how healthcare organizations and health tech companies can collaborate to improve interoperability through eConsent, moderated by Aneesh Chopra. The panel, including representatives from DocuSign and Velatura, will focus on streamlining patient consent for sharing protected health information (PHI), complying with regulations, and improving care coordination….

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Government approves further expansion of role of pharmacists 

The Cabinet has approved new legislative amendments to expand pharmacists’ responsibilities, including the ability to prescribe. The Expert Taskforce on Pharmacy in Ireland has been reviewing the role of pharmacists in primary care and has made recommendations for changes. Health Minister Stephen Donnelly has secured approval for an amendment to the Health (Miscellaneous Provisions) Bill…

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Standards of Care encourages more people with diabetes to use CGM

The 2024 ADA Standards of Care recommend continuous glucose monitoring (CGM) for all people with type 1 diabetes. CGM, along with certain insulins, can help people recognize, prevent, and treat hypoglycemia. Joanne Rinker, a board-certified advanced diabetes manager, highlighted these changes at a conference. Providers are encouraged to offer CGM to all adults on insulin,…

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Intra-Cellular reports positive results in depression study

Intra-Cellular Therapies announced positive results from a Phase 3 clinical trial for its antipsychotic medicine Caplyta in treating major depressive disorder. The study showed a significant reduction in depressive symptoms compared to a placebo on the MADRS scale. The drug also demonstrated benefits on a patient-reported measure of depression severity. Common side effects included dry…

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NHS England does U turn on staff mental health service after outcry by doctors

NHS England has initially decided to stop accepting new sign-ups to the NHS Practitioner Health program, which provides mental health and addiction services to healthcare professionals. This decision sparked dismay and disbelief among doctors, prompting NHS England to reverse the decision. The organization stated that they are reviewing staff support options for mental health across…

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New guidelines reflect growing use of AI in health care research

New guidelines called TRIPOD+AI have been introduced to update the reporting standards for clinical prediction models, reflecting the increasing use of artificial intelligence (AI) in medical decision-making tools. These guidelines aim to improve transparency and accuracy in studies developing and evaluating AI prediction models, emphasizing trustworthiness, fairness, and the importance of reporting. Led by researchers…

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Survey Highlights Impact of Cosmetic-Procedure Complications

A study presented at the annual meeting of the American Society for Laser Medicine and Surgery found that patients who experienced complications following dermatologic cosmetic procedures had high rates of mental health issues. Survey results from 100 individuals showed that rates of anxiety disorder, depression, body dysmorphic disorder, and PTSD were significantly higher after complications….

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Exercise Lowers Heart Disease Risk By Reducing Stress; Depression Patients At Greater Benefits: Study

Regular physical activity is important for heart health, with exercise lowering cardiovascular disease risk by reducing stress-related signaling in the brain. A study by researchers at Massachusetts General Hospital found that individuals with depression benefited the most from physical activity, with a 23% reduced risk of heart disease among participants who met recommended activity levels….

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Why Banner Health Is Scaling Automation Tech In Its Operating Rooms

Banner Health, an Arizona-based health system, is deploying Qventus’ perioperative technology across its organization after a successful pilot. Qventus, founded in 2012, offers technology that optimizes efficiency in healthcare settings. The perioperative software integrates with electronic health records and uses machine learning to maximize surgical caseloads. Banner is rolling out the technology to meet increasing…

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2024 RCGP Spring Meeting Conference Report

The 2024 Spring Meeting of the ROI Faculty RCGP at Queens University Belfast had an ‘all-island’ feel, with presentations on clinical cases, cancer care, political challenges in Northern Ireland, and the role of general practice in society. Winners of the Clinical Case Presentation Competition from UCC presented a case for varicella immunization, while Trinity College…

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Lark Health appoints chief growth officer for GLP-1 tech and more digital health hires

Lark Health has appointed Darren Eckberg as its chief growth officer to lead the expansion of its AI-enabled GLP-1 cost-containment technology. The company offers digital chronic-condition management services aimed at reducing medication costs. Additionally, Parsley Health has named Chris Ricaurte as co-CEO to help with financial stewardship and strategic leadership. Similarly, Array Behavioral Care has…

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Concerns linger for interchangeable biosimilar switch ‘without prescriber knowing’

Dr. Edward V. Loftus Jr. discusses the use of interchangeable biosimilars in patients with inflammatory bowel disease in a video exclusive for Healio. The availability of interchangeable biosimilars like Cyltezo, Abrilada, and Wezlana has increased access to costly medications for patients. Dr. Loftus explains that interchangeable biosimilars have been studied more than regular biosimilars and…

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Cerebral to pay $7 million fine, limit health data use for ads

Telehealth company Cerebral has agreed to limit the use of consumer health data for advertising and pay $7 million to settle charges of disclosing personal health information to third parties. The Federal Trade Commission ordered Cerebral to stop using health information for advertising purposes. The company, known for providing counseling services and prescriptions for mental…

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Predicting the risks of kidney failure and death in adults with moderate to severe chronic kidney disease: multinational, longitudinal, population based, cohort study

This study developed and tested a new prediction tool, called KDpredict, to predict the risk of kidney failure and mortality in individuals with moderate to severe chronic kidney disease. The study used data from Canada, Denmark, and Scotland to train and test the tool. KDpredict outperformed the current benchmark model for kidney failure risk prediction,…

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Environmental stressors linked to fetal brain development challenges

Researchers reviewed the impact of environmental factors on fetal brain development, focusing on inflammation and oxidative stress as common denominators across various stressors. They emphasize the importance of healthy intrauterine environments for promoting fetal brain development and stress the need to reduce modifiable stress factors during pregnancy. Factors like maternal nutrition, gut microbiota, obesity, smoking,…

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Living With Crohn’s: My Daily Routine

Michelle Pickens struggled with health issues since childhood, including severe digestive problems and fatigue, eventually diagnosed with Crohn’s disease in 2015. She manages her symptoms through medication, including immunosuppressive infusions, and prioritizes self-care and stress management. Motherhood has added challenges, as she had to make tough decisions during pregnancy and adjusts her schedule to balance…

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One-Minute Speech Test Could Help Assess Dementia Risk

Research suggests that analyzing temporal changes in speech could be a simple way of detecting mild cognitive impairment and identifying the risk of developing dementia. The Speech-Gap Test focuses on temporal speech parameters such as speech rate, hesitations, and silent pauses. It is a tool for initial screening, not diagnosis, to quickly flag patients with…

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Dr. Peter Rentrop Shares Medical Technology That Is Revolutionizing The Future Of Heart Health In Cardiology

Dr. Peter Rentrop discusses how cutting-edge medical technologies are revolutionizing the field of cardiology. Innovations such as smart wearables with ECG capabilities, AI for enhanced diagnostics, telecardiology for remote care, minimally invasive procedures, and 3D printing for surgical planning are transforming the way heart health is approached. These advancements allow for continuous monitoring, more accurate…

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