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Study shows extending interval between colonoscopies feasible after negative result

For individuals without a family history of colorectal cancer (CRC), increasing the interval between colonoscopies for those with a first colonoscopy with negative findings seems safe and can avoid unnecessary colonoscopies, according to a study published online May 2 in JAMA Oncology. Qunfeng Liang, from the German Cancer Research Center in Heidelberg, and colleagues assessed…

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How music affects the cognitive health of older adults

Credit: Andrea Piacquadio on Pexels Listening to music benefits older adults’ cognitive health, even if it’s music they haven’t heard before or don’t enjoy very much, according to a study by Simon Fraser University and Health Research BC researchers. Led by SFU neuroscientist Sarah Faber, the study published in Network Neuroscience discovered that listening to…

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Analysis shows gender and racial disparities in pulmonary embolism treatment

New data from the REAL-PE analysis investigated catheter-based pulmonary embolism (PE) treatment, showing women and Black people were less frequently treated with minimally invasive therapy compared to men or non-Black patients. The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions. PE is often caused by blood…

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MHFA training for correctional officers may boost mental health support in prisons

According to Rutgers Health researchers, training correctional officers in Mental Health First Aid (MHFA) for adults, a 7.5-hour national education program from the National Council of Mental Wellbeing, may help provide them with the necessary skills to effectively identify signs and symptoms of mental distress and advocate for incarcerated individuals facing mental health crises. Led…

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Study shows high rates of hip osteoarthritis among older adults with spinal deformity

Credit: Unsplash/CC0 Public Domain One-third of patients undergoing surgery for adult spinal deformity (ASD) also have severe osteoarthritis (OA) of the hip—which is associated with worse spinal alignment and physical functioning, reports a study in the Journal of Bone & Joint Surgery. These differences persist even following operative treatment of ASD, according to the new…

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Novel vaccine approach targets AML and other blood cancers

Acute myeloid leukemia (AML) is a type of blood cancer that forms in the soft marrow of the bones, typically attacking cells that would otherwise form the key component of the body’s immunodefense system, white blood cells. In a new study published in Blood Advances, researchers from the UChicago Pritzker School of Molecular Engineering’s Hubbell Lab created with a…

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NK cells’ role in cancer therapy resistance unveiled

Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs destructive immune reactions. Researchers from the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim (UMM) now discovered that NK…

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Mental health first-aid training may enhance mental health support in prison settings

Credit: CC0 Public Domain According to Rutgers Health researchers, training correctional officers in Mental Health First Aid (MHFA) for adults, a 7.5-hour national education program from the National Council of Mental Wellbeing, may help provide them with the necessary skills to effectively identify signs and symptoms of mental distress and advocate for incarcerated individuals facing…

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Exploring molecular landscapes of cancer in Hispanic/Latin American patients

A new editorial paper was published in Oncoscience (Volume 11) on April 22, 2024, entitled, “Exploring oncogenic driver molecular alterations in Hispanic/Latin American cancer patients: A call for enhanced molecular understanding.” In this new editorial, researcher Rafael Parra-Medina from Fundación Universitaria de Ciencias de la Salud and Instituto Nacional de Cancerología begins by discussing Latin…

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Birdwatching can help students improve mental health, reduce distress

Credit: Pixabay/CC0 Public Domain For college students seeking to improve their mental health, a potential answer may be right outside their window: birdwatching. A new study finds people who have nature-based experiences report better well-being and lower psychological distress than those who do not. Birdwatching in particular yielded promising results, with higher gains in subjective…

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Research shows interferon-beta regulates excessive alternative splicing in multiple sclerosis

Graphical abstract. Credit: Journal of Interferon & Cytokine Research (2024). DOI: 10.1089/jir.2024.0032 A new study found extensive alternative splicing of messenger RNA in the blood cells of untreated multiple sclerosis patients compared to healthy controls. The study, which showed that highly dysregulated alternative splicing was largely corrected by interferon-ß (IFN-ß) therapy, is published in the…

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New data reveals optimal timing for percutaneous coronary intervention in TAVR patients

New data reveals that percutaneous coronary intervention (PCI) can be safely performed before, during, or after transcatheter aortic valve replacement (TAVR) for patients with stable coronary artery disease (CAD). The results from the analysis were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions. For those with CAD, PCI and…

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Study shows ChatGPT can be helpful for Black women’s self-education about HIV, PrEP

Credit: Unsplash/CC0 Public Domain The artificial intelligence (AI) chatbot called ChatGPT is a powerful way for Black women to educate themselves about HIV prevention, as it provides reliable and culturally sensitive information, according to a study in The Journal of the Association of Nurses in AIDS Care. “In addition to immediately available information, regardless of…

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‘Get this done’, WHO chief tells pandemic accord talks

Credit: Pixabay/CC0 Public Domain WHO chief Tedros Adhanom Ghebreyesus on Friday told countries negotiating a global agreement on handling future pandemics to “get this done”, as they hit the half-way stage in last-ditch talks. World Health Organization member states have spent the last two years drafting an international accord on pandemic prevention, preparedness and response,…

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Key transport systems fuel rapid E. coli growth in UTIs

Through a quirk of anatomy, women are especially prone to urinary tract infections, with almost half dealing with one at some point in their lives.  Scientists have been trying to figure out for decades how bacteria gain a foothold in otherwise healthy people, examining everything from how the microbes move inside and stick to the…

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More than half of older adults with intellectual disability take psychotropic medicines, shows study

Credit: Unsplash/CC0 Public Domain The Examining Quality, Use and Impact of Psychotropic (Use) in older adults with intellectual disabilities (EQUIP) study, has revealed that more than half of older adults with intellectual disability take psychotropic medicines, including antipsychotics and antidepressants used to treat mental illness. While these medicines are critical to treat mental illness and…

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Unlocking glioblastoma’s immune suppression mechanism

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body’s defenses. The lab’s discovery was published in the paper, “Glucose-driven histone lactylation promotes the…

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The key role of Galectin-3 in brain tumor development

Credit: Anna Shvets from Pexels A research group at the Department of Biochemistry and Molecular Biology of the University of Seville has made a significant advance by discovering the crucial role of the protein Galectin-3 in the progression of various types of brain tumors. In these tumors, the most abundant immune system cells, microglia and…

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Scientists discover new immunosuppressive mechanism in brain cancer

Graphical abstract. Credit: Immunity (2024). DOI: 10.1016/j.immuni.2024.04.006 The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so that the tumor can grow unimpeded by the body’s defenses. The lab’s discovery was published in the paper, “Glucose-driven histone…

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More Relief for Crohn’s on the Horizon With New Treatments

More than 1 million Americans live with Crohn’s, a chronic and sometimes crippling inflammatory bowel disease that affects the intestines and leads to digestive issues. While some people may have mild symptoms or even be symptom-free at times, others get severe belly pain, diarrhea, fatigue, weight loss, anemia, and other life-threatening complications. So far, the…

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Women and Black patients less likely to receive catheter-based treatment for pulmonary embolism

Credit: Pixabay/CC0 Public Domain New data from the REAL-PE analysis investigated catheter-based pulmonary embolism (PE) treatment, showing women and Black people were less frequently treated with minimally invasive therapy compared to men or non-Black patients. The late-breaking results were presented today at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions. PE is…

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Microbiota Therapeutics Could Become Strong Ally in IBD Tx

Microbiota therapeutics, such as fecal microbiota transplantation (FMT), could offer more diverse, personalized treatment options for patients with inflammatory bowel disease (IBD), particularly for those with no response or resistance to existing therapies, according to a new review. Treatments that target the microbiome could help when combined with current drugs that alter the immune system,…

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Competition from ‘skinny label’ generics saved medicare billions, according to report

Credit: CC0 Public Domain An analysis of 15 name-brand drugs and their “skinny label” generic counterparts found that competition from these counterparts saved Medicare Part D nearly $15 billion from 2015 to 2021. Skinny labeling allows generic drug manufacturers to exclude labeling information that remains patent-protected by the brand name manufacturer. However, a recent federal…

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Extreme Temps Tied to Increased Stroke Death, Disability

A global increase in stroke-related death and disability has been linked to extreme temperatures related to climate change, data from a 30-year global study showed. In the first study to assess the global stroke burden attributed to nonoptimal temperatures, investigators found that in 2019, more than 500,000 people around the world died of stroke linked…

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Launching an Obesity Medicine Practice? Key Considerations

DENVER — With the demand for anti-obesity drugs continuing to soar and the provision of supportive care that is essential with their use lacking, the need for professional, highly skilled practices specializing in obesity medicine has never been higher, said an expert offering key recommendations for launching such a practice at the Obesity Medicine 2024…

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Serious Mental Illness Tied to Multiple Physical Illnesses

Serious mental illness (SMI), including bipolar disorder or schizophrenia spectrum disorders, is associated with a twofold increased risk for comorbid physical illness, results of a new meta-analysis showed. “Although treatment of physical and mental health remains siloed in many health services globally, the high prevalence of physical multimorbidity attests to the urgent need for integrated…

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A common type of fiber may trigger bowel inflammation

Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 Inulin, a type of fiber found in certain plant-based foods and fiber supplements, causes inflammation in the gut and exacerbates inflammatory bowel disease in a preclinical model, according to a new study by Weill Cornell…

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In Angina, Gene Therapy Coaxes Heart Vessel Growth

LONG BEACH, California — An experimental new gene therapy has specialists questioning whether heart vessel growth to restore blood flow could actually be possible in refractory angina after bypass surgery. “These patients by definition have exhausted all medical and surgical options in terms of revascularization,” reported lead study investigator Kenta Nakamura, MD, an interventional cardiologist…

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No Evidence of Dementia, Brain Atrophy With Antidepressant Use

Antidepressant medication use is not associated with long-term cognitive decline, brain atrophy, or dementia risk, according to results from a prospective cohort study published in Alzheimer’s and Dementia. Although antidepressants are used widely and have become more frequently used among older adults, the long-term effects of antidepressant use on cognition and dementia remain uncertain. To…

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