Value for money checks over NHS spending are shrouded in uncertainty owing to audit delays, weaknesses in financial systems, and backlogs, MPs have said. The Commons public accounts committee also raised concerns about the level of money spent on settling clinical negligence cases, which hit £2.6bn in the most recent year. A report from the…
According to the data of the Kobe University research team, the HIV substrain dominant in Southeast Asia was brought to Thailand around 1977, from where it started to spread through this part of the world. The virus was brought to Indonesia at least three different times, sometimes via different countries such as Vietnam and Laos….
On April 29th, 2024, the U.S. FDA granted full approval for Seagen Inc.’s TIVDAK® (tisotumab vedotin) targeting tissue factor (TF) for the treatment of patients with recurrent or metastatic cervical cancer who have progressed on or after chemotherapy. This marks a significant advancement in the therapeutic landscape for cervical cancer, highlighting the potential of antibody-drug…
NEW YORK CITY — Psychiatric comorbidities are highly prevalent in patients with eating disorders (EDs), a large study showed. In a propensity-matched cohort of young adults with and without EDs, a wide variety of psychiatric disorders including depression and anxiety, as well as cannabis and alcohol use disorders, were more common in those with EDs,…
Almost one-fourth of patients with insulin-dependent diabetes aged 16 years and older experience an eating disorder, a study has revealed. Type-1 diabetes is the type of diabetes commonly known as insulin-dependent, as the autoimmune disorder attacks the body’s insulin-producing cells in the pancreas. Patients with type 2 diabetes may also need insulin as they may…
Alpha Sophia, a premier platform for commercial intelligence in healthcare, has launched its new podcast series, Alpha Sophia Spotlight. Aimed at medtech startups and small to medium-sized businesses (SMBs), the series features interviews with industry innovators and leaders, hosted by Alpha Sophia’s own executives. The podcast delves into go-to-market strategies, development, and commercialization of medtech and…
Survey highlights impact of autoimmune disease on patients’ lives Campaigners have called for greater lupus visibility as a new survey has shown how the condition affects people’s lives. Lupus, also known as Systematic Lupus Erythematosus (SLE), is a complex autoimmune disease that is experienced differently by each person, and causes a variety of symptoms, including…
A 30-year-old woman presents to the emergency department (ED) with headache, nausea, vomiting, diarrhea, and abdominal pain that started 1 day ago. The patient reports 3 episodes of nonbilious, nonbloody vomiting with concomitant bilateral extremity weakness lasting about 15 minutes and 2 episodes of nonbloody diarrhea. She reports intermittent episodes of generalized body aches and…
ST. CHARLES, Mo. — Democrat Lucas Kunce is trying to pin reproductive care restrictions on Sen. Josh Hawley (R-Mo.), betting it will boost his chances of unseating the incumbent in November. In a recent ad campaign, Kunce accuses Hawley of jeopardizing reproductive care, including in vitro fertilization. Staring straight into the camera, with tears in…
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After seeing its last deal go bust in the face of regulatory scrutiny, Maze Therapeutics has found another suitor for its experimental Pompe disease treatment. Bay Area-based Maze and Shionogi said Friday that the Japanese pharma company had licensed the drug, called MZE001, with an upfront payment of $150 million. The global deal includes additional,…
GPs in Northern Ireland have agreed changes to the general medical services (GMS) contract, the BMA has said. The BMA’s Northern Ireland GP committee (NIGPC) has agreed changes for 2024-25, with the Department of Health agreeing to further work to overhaul the contract from 2025 onwards.1 The association said that NIGPC had also secured £5…
Credit: Pixabay/CC0 Public Domain Researchers at the University of California San Diego School of Medicine have shed new light on the changes in metabolism that occur between birth and the presentation of autism spectrum disorder (ASD) later in childhood. The researchers discovered that a small number of biochemical pathways are responsible for the majority of…
In a recent review published in the Scientific Reports, a group of authors used a graph-convolutional neural network (NN) to predict and analyze the thermal decomposition products of e-liquid flavors, correlating them with mass spectrometry (MS) data to assess potential health risks. Study: Forecasting vaping health risks through neural network model prediction of flavour pyrolysis reactions….
TOPLINE: Exposure to drinking water contaminated with arsenic below the current regulatory limit is associated with an elevated risk for type 2 diabetes (T2D) in urban US communities, with the correlation being stronger in women and individuals with a lower body mass index (BMI). METHODOLOGY: US residents are exposed to inorganic arsenic exposure, a potential…
Faster aging is often linked to an unhealthy lifestyle, poor sleep and eating habits, and stress. Researchers have now discovered that discrimination could be a factor that could accelerate aging. Earlier studies have shown that people who experience discrimination based on their identity, which may be their race, gender, weight, or disability, face negative health…
Cybercriminals don’t seem like they will stop using healthcare institutions as target practice anytime soon, as another major organization fell victim to a cyberattack this week. Ascension, a St. Louis-based health system with 140 hospitals across 19 states, detected a hacker’s activity in its systems on Wednesday, it said in a notice posted on its…
Produodopa provides infusion of levodopa-based drug combination to patients Irish patients with advanced Parkinson’s disease are to benefit from a new wearable kit that provides 24-hour treatment for their condition. Health authorities here have granted reimbursement for Produodopa, which uses a pump to release medicine into the bloodstream. The treatment is combination of foslevodopa and…
Telehealth and medical transportation company DocGo reported a data breach in an SEC filing on May 7. The company stated it identified a cybersecurity incident in which consumers’ protected health information was accessed and acquired regarding the company’s U.S. ambulance transportation business. The company said it took steps to contain and respond to the incident,…
Noam N. Levey JACKSONVILLE, Ill. — Heather Crivilare was a month from her due date when she was rushed to an operating room for an emergency cesarean section. The first-time mother, a high school teacher in rural Illinois, had developed high blood pressure, a sometimes life-threatening condition in pregnancy that prompted doctors to hospitalize her….
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LONDON — Novavax, the beleaguered maker of a Covid-19 vaccine, just got a boost of its own. The French pharma company Sanofi on Friday said it had reached a licensing deal to sell Novavax’s Covid shot going forward as well as to try to combine the vaccine with Sanofi’s own flu shot. The pact includes…
Tom Nolan, clinical editor; sessional GP, Surrey The BMJ, London Tom Nolan reviews this week’s research TAVI for severe aortic stenosis and low surgical risk A randomised controlled trial compared transcatheter aortic valve implantation (TAVI) with surgical aortic valve replacement (SAVR) in people with severe, symptomatic aortic stenosis and a low surgical risk. The multicentre…
Credit: Unsplash/CC0 Public Domain Hectic last-ditch talks aimed at striking a landmark global agreement on handling future pandemics rolled into the final day on Friday with a deal still up in the air. Two years of work on drafting an international accord on pandemic prevention, preparedness and response are coming to the crunch, with just…
In a recent meta-analysis published in the journal Nature, researchers collate, analyze, and discuss the results from over 2,938 published observations to elucidate the global change drivers contributing highest to global surges in infectious diseases, both amongst humans and other non-human organisms. Their study reveals that biodiversity losses, species introductions, climate change, and chemical pollutants…
Processed foods have been around for millions of years, since early hominoids first cooked meat over open fires. Humans later learned processing techniques to make food safer, tastier, and longer lasting. But with the advent of ultraprocessed foods (UPFs), we may have reached the turning point where modern food production methods are coming at an…
Working on the night shift for as little as three days can disrupt protein rhythms, raising the risk of diabetes, a recent study has revealed. The researchers of the latest study from the Washington State University and the Pacific Northwest National Laboratory explored how night shift workers are more prone to metabolic disorders, including diabetes…
Naoki Okamura, the CEO of Astellas Pharma, and his senior leadership team were in South San Francisco on Wednesday to mark the opening of the company’s West Coast Innovation Center, a gleaming $90 million, state-of-the-art building that co-locates several of the company’s operations strewn over the Bay Area in one location. “Our gene therapy organization…
No further out of stock issues are envisaged in the immediate future A. Menarini wish to announce that Frovex 2.5mg tablets are back in stock. No further out of stock issues are envisaged in the immediate future. We would like to apologise for any inconvenience caused. Further information contact:Peter Tobin; e: Ptobin@menarini.ie; t: 01 284…
Access to bivalent COVID-19 vaccinations through September 2023 throughout the United States was enabled by a government/pharmacy partnership program that may provide a model for routine vaccination services and future public health emergencies, according to study findings published in Morbidity and Mortality Weekly Report (MMWR). The Federal Retail Pharmacy Program (FRPP) is a collaboration of…
A mobile application used to assess sports-related head and brain injuries is now being tested for detecting and monitoring neurological disorders. BrainEye’s mobile test is now being studied in clinical trials at The Alfred Hospital in Melbourne. It digitises the traditional eye movement test, which is done in 60 seconds through a mobile device, and…
The Host A new analysis finds that graduating medical students were less likely to apply this year for residency training in states that ban or restrict abortion. That was true not only for aspiring OB-GYNs and others who regularly treat pregnant patients, but for all specialties. Meanwhile, another study has found that more than 4…
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Exact Sciences reported first-quarter revenues this week that beat market expectations, and the cancer detection company’s executives still believe they’re on track to meet expected 2024 revenue. That’s usually good news. Yet Exact shares are down nearly 11% on Thursday, dipping to $53.12 within the first few hours of trading. During after-hours trading on Wednesday,…
Julian Hirt, research fellow and lecturer1 2 3, Thomas Nordhausen, research fellow4, Thomas Fuerst, medical information specialist5, Hannah Ewald, medical information specialist5, Christian Appenzeller-Herzog, medical information specialist5 on behalf of the TARCiS study group 1Pragmatic Evidence Lab, Research Centre for Clinical Neuroimmunology and Neuroscience Basel, University Hospital Basel and University of Basel, Basel, Switzerland 2Department…
First introduced five decades ago, MRI scanners are now a cornerstone of modern medicine, vital for diagnosing strokes, tumors, spinal conditions and more, without exposing patients to radiation. A magnetic resonance imaging device built with off-the-shelf parts and paired with AI matched the performance of high-end MRI machines, according to a study published Thursday that could…
Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions. The finding, from a study led by scientists at Washington State University and the Pacific Northwest National Laboratory, provides new clues as to…
May 9, 2024 – Were you born with family genes that predict a short life? Fear not; it turns out that having such genes is not a death knell but an opportunity. In fact, new findings suggest that adopting and sticking to a combination of lifestyle changes may be one of the most important ways…
The medication vibegron led to improvements in symptoms of overactive bladder and overall quality of life in men undergoing treatment for benign prostatic hyperplasia, according to findings from a phase 3 trial presented on May 6, 2024, at the American Urological Association (AUA) 2024 Annual Meeting in San Antonio, Texas, and data published in The…
Welcome to this week’s issue of The Week in Medicine – a round-up of all the happenings in the world of Irish medicine It’s hard to know where to put ‘WellFest’ in the medical compendium. For those of you who aren’t aware of it, WellFest is taking place next weekend in the Royal Hospital Kilmainham…
Syra Health, a healthcare technology company that provides tools to analyze population health, reported revenue of $1.7 million in the first quarter of 2024, compared to $1.2 million in the same period last year. The company noted that its strong growth was due to its Population Health offering, which grew 212% year over year, and…
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You’re reading the web edition of D.C. Diagnosis, STAT’s twice-weekly newsletter about the politics and policy of health and medicine. Sign up here to receive it in your inbox on Tuesdays and Thursdays. Ways & Means strikes first Yesterday, leaders of the House Ways & Means Committee passed a two-year extension of expiring Medicare telehealth provisions with…
Eric Slade, health economics adviser1, Laura Berg, systematic reviewer1, Katharina Dworzynski, guideline lead1, Ranjit Manchanda, professor of gynaecological oncology and consultant gynaecological oncologist, guideline topic adviser2 3 4 on behalf of the Guideline Committee 1National Institute for Health and Care Excellence, London 2Wolfson Institute of Population Health, Queen Mary University of London 3Barts Health NHS…
Credit: Unsplash/CC0 Public Domain The reminders are everywhere. When a woman turns 40, doctors say she should begin receiving yearly mammograms to detect breast cancer. You see it on posters, ads and buttons. Doctors beat the drum forcefully and often because the stakes are high. While both women and men can develop breast cancer, the…
A recent Nature Mental Health study assessed the developments in ensemble deep learning (EDL) models used to characterize and estimate AD. Study: Ensemble deep learning for Alzheimer’s disease characterization and estimation. Image Credit: SewCreamStudio/Shutterstock.om Ensemble deep learning EDL combines the outputs of several machine learning (ML) models to enhance their generalization performance. The traditional approach to building…
Ablation of the gastric fundus to reduce production of the “hunger hormone” ghrelin resulted in decreased appetite and significant weight loss among participants in a small first-in-human trial. “Patients reported a decrease in hunger, appetite, and cravings, and an increase in control over-eating,” said senior study investigator Christopher McGowan, MD, a gastroenterologist in private practice…
For many women, the days after childbirth may not be as exciting and thrilling as they expected during their pregnancy. In the first days and weeks following childbirth, they may experience a stage of “baby blues” accompanied by mood swings, bouts of crying, and heightened anxiety. In some cases, these symptoms become severe and long-lasting,…
One of the more famous precepts of Dr. William Osler (1849-1918), widely regarded as the Father of Modern Medicine and the “greatest diagnostician ever to wield a stethoscope,” was to, “treat the whole patient not just the disease.” The phrase he specifically used was, “the good physician treats the disease; the great physician treats the…
Dr Ray O’Connor takes a look at the latest clinical studies on asthma AsthmaIt is no harm to remind ourselves as doctors why we do this job, and the occasional dire consequences if due process is not followed. I begin this piece with an account of the coroner’s report on the death of a 10-year-old…