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Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning. I’m making another plea to please fill out our brief survey! We want to know how to make this newsletter more informative and helpful for you. I assure you that we are reading…
Doctors have raised concerns about the future training prospects of medical students after the government announced it would fund 350 additional medical school places in England for the academic year 2025-26. In its NHS Long Term Workforce Plan published last year the government promised it would double medical school places in England, from 7500 to…
Study Protocol. At 8 PM, participants encoded images from the EPT, emotional picture task, followed by an immediate test. Next, participants slept either at home or in the lab depending on their method of testing being remote or in-person, respectively. Upon awaking, participants reported the presence and description of their dreams and completed a delayed…
A deadly strain of cholera bacteria that emerged in Indonesia back in 1961 continues to spread widely to this day, claiming thousands of lives around the world every year, sickening millions -; and, with its persistence, baffling scientists. Finally, in a study published today in Nature, researchers from The University of Texas at Austin have discovered…
NEW ORLEANS — Adrenalectomy for the treatment of mild autonomous cortisol secretion (MACS) appears to improve bone quality but not bone density, new data suggested. Formerly called “subclinical Cushing Syndrome,” MACS is the name now used when a patient with an incidentally discovered adrenal mass has no overt Cushing symptoms but has cortisol levels greater…
The Government has committed to providing increased and recurring funding for an innovative new initiative for adults with ADHD. The Understanding and Managing ADHD in Adults Programme (UMAAP) is a six-week workshop that combines psycho education on adult ADHD with acceptance and commitment therapy (ACT). Since beginning as a pilot project in 2022 it has…
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BOSTON — The tables set up near the entrance of the Big Night Live concert venue looked like a typical merch spread. But instead of band T-shirts and buttons, there were plastic models of human noses and a handful of naloxone nasal sprays. This unusual display was part of a medical training for bar and restaurant…
See Chai Carol Chan, academic clinical fellow in general practice1, Rebecca Wright, honorary GP teaching fellow1, Azeem Majeed, professor of primary care and public health1 1Imperial College London X: @carolchancarol, @Azeem_Majeed In some parts of England, there are proposals to divide NHS primary care services. NHS England’s strategy aims to separate patients with “same-day” acute…
Credit: Pixabay/CC0 Public Domain Artificial intelligence (AI) computer programs that process MRI results show differences in how the brains of men and women are organized at a cellular level, a new study shows. These variations were spotted in white matter, tissue primarily located in the human brain’s innermost layer, which fosters communication between regions. The…
A newly discovered Zika virus-specific synthetic molecule is capable of differentiating Zika-immune patient samples from samples of patients previously infected with the related dengue virus. The technology may lead to the development of better diagnostics and vaccine candidates, scientists announced today in the Proceedings of the National Academy of Sciences. The study, led by researchers…
Clinical guidelines on age-related hearing loss (ARHL), published in Otolaryngology–Head and Neck Surgery, highlight referral recommendations for all clinicians, including primary care doctors, who often are the first clinicians to screen for and address the condition. Betty S. Tsai Do, MD, with the Department of Head & Neck Surgery at Kaiser Permanente in Walnut Creek,…
An emergency response charity – Critical – has launched a new fleet of rapid response cars as it aims to expand its life-saving network of medical volunteers. Critical currently has a team of ten doctors, including consultants in emergency medicine, who respond to serious and life-threatening incidents and illnesses in their local areas. The clinicians…
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SAN DIEGO — Companies racing to read the genome accurately, quickly, and affordably have hit a snag recently, with several firms reporting that their growth has slowed, stalled, or reversed. Upstart Element Biosciences is hoping it can succeed despite the challenging market conditions. The San Diego firm launched a $290,000 sequencer, dubbed Aviti, in March…
African countries increased their health workforce from 1.6 million in 2013 to 5.1 million in 2022, alongside improvements in training and data use, a review by the World Health Organization Africa region office has found.1 The decade also saw a 44% increase in the number of countries with national health workforce strategies, from 27 in…
A summary of behavioral data in a simple value-based decision-making experiment. A: Reported mental effort (y-axis) is plotted against the difference in reported option values (x-axis), for all trials (black), high-confidence trials (blue) and low-confidence trials (red), respectively. B: Decision time, same format. C: The probability of choosing the first option (y-axis) is plotted against…
Jacqueline Saa has a genetic condition that leaves her unable to stand and walk on her own or hold a job. Every weekday for four years, Saa, 43, has relied on a home health aide to help her cook, bathe and dress, go to the doctor, pick up medications, and accomplish other daily tasks. She…
VIENNA — Nearly one third of anterior cruciate ligament (ACL) injuries appear to heal without surgery, according to an analysis of three-dimensional MRI data taken from the NACOX study, presented as a late-breaking poster at the recent World Congress on Osteoarthritis (OARSI) 2024 Annual Meeting. At 2 years after injury, three-dimensional MRI showed that 13…
Dr Ray O’Connor takes a look at the latest clinical studies on mental health AnxietySocial Anxiety Disorder (SAD) is highly prevalent and debilitating disorder. Treatments exist but are not accessible and/or helpful for all patients, indicating a need for accessible treatment alternatives. The aim of this randomized, clinical trial1 was to evaluate internet-delivered psychodynamic therapy…
Jacqueline Saa has a genetic condition that leaves her unable to stand and walk on her own or hold a job. Every weekday for four years, Saa, 43, has relied on a home health aide to help her cook, bathe and dress, go to the doctor, pick up medications, and accomplish other daily tasks. She…
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WASHINGTON — On a bright June day in 2018, one of the nation’s top regulators waved groceries in the air, quizzing the secretary of agriculture on which agency is charged with monitoring different types of food. Scott Gottlieb, the commissioner of the Food and Drug Administration at the time, grinned widely as he held liquid…
Matt Morgan, consultant in intensive care medicine Cardiff mmorgan{at}bmj.comFollow Matt on X @dr_mattmorgan One of the joys of writing this column is receiving emails from readers who work across a wide spectrum of medicine, from students to retired professors. I read one such email from a retired, fellow Cardiff alumnus in response to my last…
Credit: CC0 Public Domain More than 20,000 volunteers have been recruited to a resource aimed at speeding up the development of much-needed dementia drugs. The cohort will enable scientists in universities and industry to involve healthy individuals who may be at increased risk of dementia in clinical trials to test whether new drugs can slow…
In a recent study published in Nature Aging, researchers conducted a randomized clinical trial (RCT) to investigate whether a health education intervention offered to Chinese college students will increase severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) booster vaccinations among their grandparents. Study: Influence of grandchildren on COVID-19 vaccination uptake among older adults in China: a parallel-group,…
The daily injectable vosoritide (Voxzogo) appears promising for various genetic causes of short stature in children, new phase 2 trial data suggested. Vosoritide is a C-type natriuretic peptide analog that binds its receptor on chondrocytes, promoting growth by inhibiting the extracellular signal-regulated protein kinases 1 and 2-mitogen-activated protein kinase pathways. It was approved in 2021…
Four-year study found that patients lost 10 per cent of body weight on average Revolutionary obesity drug semaglutide may deliver heart health benefits, even in patients who lose a modest amount of weight on the treatment, major new research has found. In two long-term studies involving more than 17,000 adults with overweight or obesity but…
In early 2020, with reports of covid-19 outbreaks making dire headlines, Trever Schapers worried about her father’s safety in a nursing home in Queens. She had delighted in watching her dad, John Schapers, blow out the candles on his 90th birthday cake that February at the West Lawrence Care Center in the New York City…
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Deciding whether to withdraw life support after a severe traumatic brain injury is extremely difficult. Loved ones are faced with balancing their hopes for recovery with the desire not to prolong suffering, and clinician insight is essential. With the support of critical care physicians, most decisions on whether to end life support are made within…
Janice Hopkins Tanne New York The American Medical Association (AMA) has expressed concern about the widening health disparities between rural and urban communities, with death rates around 20% higher for the 46 million Americans who live in rural areas than for those who live in urban areas.1 Many people in rural communities also live below…
Credit: CC0 Public Domain The idea that biology is not destiny is hardly new. Studies in twins have shown that even among identical pairs—those sharing 100% of their DNA—the same disease genes do not turn into full-blown illness in both individuals. Most human diseases are fueled by both genetic and environmental factors. Genes account for…
Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus. Herpes…
Charles Powell, MD, said he sometimes has a hard time persuading patients to start on low-dose vaginal estrogen, which can help prevent urinary tract infections and ease other symptoms of menopause. Charles Powell, MD Many women fear taking these vaginal products due to what Powell considers excessively strong warnings about the risk for cancer and…
Excess sugar in the diet is a known risk factor for developing metabolic disorders, including obesity and diabetes. Researchers have now found that the source of sugar matters more than the amount when it comes to the development of obesity in children. The study results presented at the European Congress on Obesity revealed that the…
Welcome to this week’s issue of The Week in Medicine – a round-up of all the happenings in the world of Irish medicine As a longtime fan of Benjamin Franklin – whose long and fruitful life has been an inspiration to many – I was intrigued to see Jamie Raskin referring to him in the…
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Credit: Pixabay/CC0 Public Domain Findings from the Kennedy Krieger Institute emphasize the critical importance of integrated care for children with epilepsy and co-occurring psychiatric issues, shedding light on the negative effects of fragmented care. Expertise on the issue has been published in Epilepsy Currents. Epilepsy is a neurological disorder that causes recurring seizures. The article…
Electronic vapor products (EVPs), also known as e-cigarettes or vaping devices, have an allure because of their marketed image as a safer alternative to traditional cigarette smoking and for their variety of appealing flavors. Yet, they contain many substances beyond nicotine, including propylene glycol, glycerin, flavorings and potentially harmful chemicals such as formaldehyde and metals,…
TOPLINE: Higher endoscopist polyp detection rates are significantly associated with fewer negative colonoscopies after positive stool tests, suggesting the need for new detection benchmarks, researchers say. METHODOLOGY: Researchers evaluated the degree to which positive stool tests followed by negative colonoscopy (“false-positive” stool tests) vary with endoscopist quality. They analyzed data from the New Hampshire Colonoscopy…
Regular cannabis use is associated with the risk of mental health issues, including anxiety and depression. The use of high-potency cannabis in teen years almost doubles the risk of developing psychotic episodes in early adulthood compared to the use of those with lower potency, a study revealed. Earlier studies have shown that the concentration of…
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Herpes simplex virus. Credit: CDC Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread…
Suddenly they appear and – like the SARS-CoV-2 coronavirus – can trigger major epidemics: Viruses that nobody had on their radar. They are not really new, but they have changed genetically. In particular, the exchange of genetic material between different virus species can lead to the sudden emergence of threatening pathogens with significantly altered characteristics….
DENVER — Two new drugs are headed toward pivotal trials after making their endpoints in phase 2 treatment-resistant epilepsy studies, while a first-in-humans study of an implantable product suggests a new direction for this disease, according to new data presented at the 2024 annual meeting of the American Academy of Neurology. Of the two drugs…
Men who have low levels of testosterone are at an increased risk of heart disease and early death, particularly from cardiovascular diseases, a study revealed. Testosterone is a male sex hormone essential for sexual development and functions in men. The normal testosterone levels range from 300 and 1,000 ng/dL. When testosterone levels are low, the…
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Credit: CC0 Public Domain A study published in Medicine & Science in Sports & Exercise reveals that people who participated in regular bicycling over their lifetime had a lower prevalence of frequent knee pain, radiographic osteoarthritis (ROA) and symptomatic radiographic osteoarthritis (SOA). Rheumatologists often encourage regular physical activity for the prevention of osteoarthritis, the most…