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Medicare Advantage overpayments discussion gets experts fired up

Medicare Advantage, a controversial health care program, is in the spotlight due to new data revealing overpayments and criticism of its quality rating system. The Medicare Payment Advisory Commission discussed these findings, leading to conclusions that the federal government overpays Medicare Advantage insurers because they attract healthier, low-cost individuals and then code their health conditions…

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John Hedges | The BMJ

John Hedges had a successful career in both military and civilian medicine, thanks to a medical cadetship with the Royal Army Medical Corps. He was commissioned in 1969, completed his house jobs, and became the garrison senior medical officer in West Germany in 1974. He then trained at the Cambridge Military Hospital in Aldershot and…

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Uncovering the link to combating muscle atrophy caused by aging and immobility

Mitochondria play an important role in muscle development, regeneration, and maintenance, and problems with these can lead to muscle diseases such as muscle atrophy. The tethering of mitochondria to the endoplasmic reticulum (ER) is found in healthy cells, and this anchoring regulates metabolism, mitochondrial morphology, and calcium homeostasis. In people experiencing muscle atrophy, there is…

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When mass spectrometry redefines the pharma industry

In this episode of omg OMx, Mike Greig from Bruker discusses the potential of mass spectrometry in pharma. He talks about his career in biotechnology, his mentor, and his passion for chemistry. He also discusses the evolution of drug development and the barriers to the marketability of mass spectrometry in the pharma industry. He mentions…

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Complacency Has Replaced Alarm in the Newest COVID Surge

The United States is currently experiencing a surge in respiratory viruses, notably the JN1 variant of COVID-19. Hospitalization and death rates are increasing, but the response to the pandemic is waning due to complacency, pandemic fatigue, and decreased resources. COVID has become normalized, leading to increased awareness of virus transmission and increased use of protective…

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Positive Phase 3 Results for New Antipsychotic in Psychosis

The results of the phase 3 EMERGENT-2 trial showed that KarXT, a combination of a muscarinic receptor agonist with an anticholinergic agent, led to significant improvements in symptoms of schizophrenia compared to a placebo. The treatment showed potential as a new class of effective and well-tolerated antipsychotic medication. It was associated with fewer side effects…

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For Precise Readings And Peace Of Mind

Monitoring your blood pressure is crucial for maintaining good health, as hypertension can cause silent damage to your heart, arteries, and kidneys. This guide helps you find the best blood pressure monitors for your needs and budget, including options for tech-savvy users, value-conscious users, and healthcare professionals. The top contenders are the Wellue Blood Pressure…

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Hydrogels potential electrodes providing ground-breaking treatment for ventricular arrhythmia

Hydrogels show promise as electrodes for treating ventricular arrhythmia, a potentially life-threatening condition. These innovative electrodes could revolutionize the treatment of this heart condition. The use of cookies for analytics, advertising, and site improvement is acknowledged, and continued site use implies agreement to their use. For more information, the Cookie Policy and Cookie Settings can…

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Menopause Startup Launches AI-Powered Hot Flash Care Product

Amira CEO Loewen Cavill was inspired to create The Terra System, a product aimed at helping women manage menopause symptoms, after her aunt suffered severe sleep disruptions from hot flashes. The AI-powered product includes a wearable bracelet to predict hot flashes and a cooling mattress pad to help regulate temperature fluctuations. Amira also launched Amy,…

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Express Scripts sued for allegedly colluding with rival PBMs to fix prices

An antitrust lawsuit has been filed against Cigna-owned online pharmacy and pharmacy benefit manager (PBM) Express Scripts by several independent pharmacies. The lawsuit alleges that Express Scripts teamed with rival PBMs to fix pharmaceutical reimbursement rates and fees, resulting in collecting a portion of the revenue. PBMs negotiate prescription prices, which can be substantially higher…

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All About the (Government) Funding

Lawmakers are struggling to fund the government and federal health programs. The Supreme Court is reviewing a case about Idaho’s abortion ban and federal law. The Biden administration is scaling back health provider conscience protections. Florida introduced legislation classifying abortion as a felony and penalizing those involved in distributing abortion pills. The FDA approved Florida’s…

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Facility fees for colonoscopy nearly 55% more at hospitals vs. ambulatory surgery centers

Researchers compared facility fees for three common colonoscopy procedures at hospitals and ambulatory surgery centers. They found that the fees were approximately 55% higher at hospitals compared to ambulatory surgery centers. The study, published in JAMA Health Forum, used data from four major insurers and included 13,287 in-network fees from hospitals and 17,052 fees from…

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In shift, Texas to cover initial consult for Afghan baby’s gene therapy

The Texas Medicaid program has agreed to cover costs for doctors to assess 4-month-old infertility patient Sufyan Pashai in Minneapolis, Minnesota. Sufyan’s older brother has metachromatic leukodystrophy (MLD), a neurodegenerative disorder caused by a gene mutation, and Sufyan is a candidate for treatment to prevent the disease from manifesting. This gene therapy called Libmeldy is…

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Tom Nolan’s research reviews—11 January 2024

A clinical editor discusses the potential fallacy of relying on easily measured data from wearable technology to inform mental health care, emphasizing the importance of considering the impact on patients. A study on lung cancer screening raises concerns about the high rate of complications found in those who undergo invasive tests after a positive screening…

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Flagging dementia patients for better hospital care

Cedar-Sinai investigators have developed a way to use electronic health records to identify hospitalized patients with dementia. The method, outlined in the Journal of the American Geriatrics Society, is designed to help care teams provide tailored and targeted interventions for patients with dementia. An algorithm searches for dementia diagnoses and appropriate prescriptions in patients’ health…

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Why This Exercise Is So Good for High Blood Pressure

The content discusses how isometric exercises have been found to be especially effective in lowering blood pressure. Isometric exercises involve holding a position to flex muscles, which constricts blood vessels leading to a buildup of metabolites and a release of nitric oxide, causing blood vessels to dilate. Research has shown that isometric exercises such as…

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So Far, No Ties Between GLP-1s and Suicidal Thoughts

The FDA has not found any evidence linking glucagon-like peptide 1 receptor agonist (GLP-1 RA) medications used for type 2 diabetes and obesity to suicidal thoughts or actions. This determination was made after reviewing clinical trial data and reports to the FDA Adverse Event Reporting System. While the agency cannot definitively rule out a small…

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Olanzapine and samidorphan combination effective for long-term treatment of schizophrenia, bipolar disorder

Olanzapine and samidorphan combination has been found to be effective for the long-term treatment of schizophrenia and bipolar disorder. This medication has shown promising results in managing the symptoms of these mental health conditions. In addition, cookies are used on the website for analytics, advertising, and to improve the site. By continuing to use the…

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Torsemide, Furosemide Have Similar Outcomes in Patients Discharged With Acute HF

The TRANSFORM-HF study found no significant difference in outcomes between torsemide and furosemide treatments for heart failure. However, patients with de novo heart failure had better outcomes compared to those with worsening chronic heart failure after hospitalization. The study analyzed patients from 60 US hospitals and found that de novo heart failure was associated with…

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Readout LOUD podcast: live from JPM 2024

The content is about the latest in the biotech industry, discussed in a podcast called “The Readout LOUD” from STAT. The podcast covers the recent turnaround in the biotech industry, with deals and positive developments at the J.P. Morgan Healthcare Conference. It also delves into topics such as the Sarepta Therapeutics saga, Nvidia’s potential impact…

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Labour launches child action plan to create “healthiest generation ever”

Labour has unveiled a child action plan aimed at creating the healthiest and happiest generation in Britain. The plan includes reducing paediatric waiting times, improving child mental health support, addressing junk food advertising, and implementing supervised toothbrushing in schools. A Labour government would establish a mission delivery board focusing on child health and inequalities. Keir…

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American Heart Association’s merit award recipients announced

The American Heart Association is celebrating 100 years by awarding its prestigious Merit Award to three researchers. Joseph Loscalzo will study natural food chemicals and their impact on heart disease. Daniel J. Rader will investigate lipid metabolism and cardiovascular diseases, while Philip S. Tsao will focus on the effects of vaping on abdominal aortic aneurysms….

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Insulin Injections at Home: What to Expect

Diabetes management with insulin involves learning to give yourself injections. Kathy Bostrom emphasizes the rapid changes in syringes and pens which have made the process easier. Syringes are prone to errors, while pens are more user-friendly. An alcohol wipe is essential while also having a sharps container. Different insulins require different times for their administration…

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Death of a Sibling Increases the Risk for Heart Disease

A new study published in JAMA Cardiology suggests that people who have experienced the death of a sibling may be at an increased risk of developing cardiovascular illnesses. The study, which analyzed data from over 2 million people in Denmark, found that individuals who lost a sibling had a 17% higher risk for overall cardiovascular…

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Elevance Health To Offer Smartphones to Some Medicaid Members

Elevance Health has partnered with Samsung, Verizon, AT&T, and T-Mobile to provide Medicaid members with smartphones and unlimited data, talk, and text at no cost. The program aims to improve access to virtual healthcare tools and bridge the digital divide for low-income individuals. The initiative is funded by the Federal Communications Commission’s Affordable Connectivity Program…

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GP required to join north Dublin city practice

A Dublin-based GP practice on the north side of the city is looking for a GP to join their team. The practice focuses on providing high-quality patient care in a sustainable work environment, serving approximately 5,200 patients. They are open to integrating new skills and have the support of the local hospital to develop skills…

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Suicide prevention telehealth provider Vita Health receives $22.5M

Connecticut-based Vita Health has raised $22.5 million in Series A funding, with participation from various investors. The telehealth platform connects individuals contemplating suicide with providers and offers teletherapy and psychiatry services. The funding will support the company’s expansion to help address the increasing rate of suicides in the U.S. Vita Health aims to tackle the…

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Consider complete pathology, surgical techniques for tibial plateau fractures

Surgeons should consider the 3D orientation of tibial plateau fractures before fixation. Understanding the fracture pathology and components is crucial in treatment, including the size and orientation of the fracture, which dictates the location of the medial plate. Methods of articular elevation depend on the degree of comminution and depression, and reducing varus medial column…

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U.K. sequencing study surfaces new findings about tumor DNA

The UK’s 100,000 Genomes Project has revealed that certain tumors are more likely to carry mutations that can inform patient care, steering treatment choices or indicating a potential familial risk. The findings from over 13,800 solid tumors in adults are already influencing clinical practice in the UK’s National Health Service, with patients diagnosed with certain…

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“Safer supply” alternatives to toxic unregulated drug markets

Adam Holland, Thomas D Brothers, Dan Lewer, Olivia M Maynard, and Mat Southwell address the urgent need for action to reduce drug-related deaths. They discuss the prescription of safer supply interventions in response to opioid toxicity and the COVID-19 pandemic in Canada. Despite controversy and concerns about limited evidence, observational studies show that opioid dispensation…

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Pangolins’ genetic makeup linked to increased coronavirus susceptibility

A study published in Scientific Reports suggests that pangolins are highly susceptible to coronavirus infection due to the pseudogenization of key immune system genes in their genome. Researchers analyzed pangolin skin and found that the host immune response pathways were not upregulated in response to infection. They also discovered that the coronavirus suppresses endogenous retrovirus…

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How Does Too Much Sugar Affect Your Body?

The average American consumes about 17 teaspoons of added sugar each day, and sugary drinks, candy, baked goods, and sweetened dairy are the main sources of added sugar. Excess sugar intake can lead to various health issues, including mood changes, joint pain, skin aging, liver damage, heart disease, diabetes, kidney damage, weight gain, and erectile…

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FDA Rejects GI Cancer Drug Over Manufacturing Issues

The FDA has rejected approval of the cancer drug zolbetuximab due to manufacturing issues. The drug, developed by Astellas, was intended for treating a specific type of gastric cancer. The FDA’s decision was related to unresolved deficiencies in the manufacturing process at a third-party facility. The company is working to resolve the issues and clarified…

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