#obesity

A collaborative effort between POSTECH, Daegu Catholic University School of Medicine, and Seoul National University has developed a novel strategy called OrthoID to identify key proteins in organelle communication. This method improves the ability to pinpoint proteins crucial for interactions between organelles, particularly between mitochondria and the endoplasmic reticulum (ER). OrthoID utilizes multiple binding pair…

Expecting twins is a double blessing, but it can also bring greater risks than a singleton pregnancy. Twin pregnancies require more monitoring and care, with the need for higher folic acid intake and increased weight gain. Pregnant with twins may experience more morning sickness, back pain, and heartburn. There is also a higher risk of…

Researchers have developed a smartphone-based tool that uses voice recordings to track mental health status by analyzing specific vocal patterns linked to mental health. This Mental Fitness Vocal Biomarker (MFVB) platform aims to complement traditional psychiatric assessments and improve self-monitoring of mental health symptoms. The tool calculates a real-time MFVB score based on eight vocal…

New research has found a link between gestational hypertension during pregnancy and cognitive decline later in life. The study suggests that women who experienced high blood pressure during pregnancy may be at a higher risk for cognitive problems as they age. This highlights the importance of monitoring and addressing gestational hypertension to prevent long-term health…

Atlantic Health System has partnered with FeelBetter, a startup based in Tel Aviv and Boston, to adopt their technology for managing polypharmacy patients who take five or more medications simultaneously. The platform aims to address the growing public health concern of senior patients being prescribed multiple medications, leading to poor health outcomes, increased healthcare costs,…

A recent study presented at the American Academy of Neurology annual meeting looked at the outcomes of treating older adults with multiple sclerosis (MS) and signs of cancer with immune checkpoint inhibitors. The study found that 13 out of 38 patients treated with immune checkpoint inhibitors had partial or complete cancer remission. Overall, the treatment…

During World War II, Nazi troops caused a man-made famine in the Netherlands known as the Dutch Hunger Winter, resulting in 20,000 deaths and long-lasting impacts on survivors’ descendants. Neuroscientist Bianca Jones Marlin investigates how trauma can be inherited across generations, particularly through changes in sensory experiences like smell. Her research with mice shows that…

Dreams are a mysterious aspect of human experience that continue to fascinate scientists and society. Recent research presented at the annual meeting of the Cognitive Neuroscience Society highlights the impact of dreams on our waking lives, including their potential influence on our perceptions of sleep quality. Studies are exploring the relationship between dreams, cognition, and…

A study conducted at the University of Jyväskylä in Finland found that genetic predisposition for higher muscle strength can predict a longer lifespan and lower risk for common diseases. The research used data from over 340,000 Finns to analyze the relationship between hereditary muscle strength, morbidity, and mortality. Individuals with a genetic predisposition for higher…

Pregnancy myths about predicting a baby’s sex persist despite advances in medical technology. These myths, such as belly shape, heart rate, ring swinging, and Drano color, have no scientific basis. While some myths seem to align with reality, like cravings and morning sickness, they are not reliable indicators. The Chinese lunar calendar is also not…

Early data suggests that new multicancer early detection (MCED) tests, such as CanScan, MERCURY, and OncoSeek, show promise in identifying cancers without routine screening options. These tests aim to accurately identify multiple cancer types with a single blood draw. CanScan covers two-thirds of new cancer cases globally and has shown promising sensitivity and specificity rates….

A study found that poorly controlled Type 1 Diabetes in children is linked to metabolic associated fatty liver disease (MASLD) regardless of overweight. This highlights the importance of managing blood sugar levels in children with Type 1 Diabetes to prevent complications such as MASLD. The study emphasizes the need for healthcare providers to closely monitor…

NationsBenefits and Instacart have partnered to offer online grocery services to Medicare Advantage, Medicaid, and commercial plan members. NationsBenefits provides supplemental benefits and member engagement solutions, while Instacart is a grocery technology company that partners with healthcare organizations for food as medicine programs. Through the partnership, health plans can offer Instacart’s delivery services as a…

Osso VR has launched the Osso Health training app for use with Apple Vision Pro, an immersive reality wearable headset. The app simulates surgical workflow for procedures such as carpal tunnel release and total knee replacement. It can also be used by patients preparing for surgery. Justin Barad, MD, co-founder of Osso VR, highlighted the…

The IRS allows most U.S. hospitals to pay no federal taxes under a vague “community benefit” standard, despite many taking advantage of patients with inflated bills. Some nonprofit hospitals even sue and garnish wages of low-income patients. Hospitals hide profits through accounting tricks and loan refinancing while avoiding taxes. Patients are often harassed for payment…

A study from the University of Sydney found that most menu items on online food delivery platforms in Australia lack nutritional information, hindering consumers’ ability to make healthy choices. The study revealed that less than 6% of menus had complete kilojoule labeling, with inconsistencies between different outlets and delivery services. The findings highlight the need…

Researchers at the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation discussed the potential benefits of using normothermic regional perfusion (TA-NRP) to re-perfuse the lungs of organ donors after cardiac death. This technique has shown promise in increasing the number of lung transplants performed and improving outcomes for recipients….

Exercise can help reduce the effects of aging and improve physical and mental health by reducing the risk of chronic disease and improving symptoms of anxiety and depression. Being physically fit can make you functionally years younger and improve muscle strength, endurance, and flexibility. It is recommended that adults do moderate to vigorous-intensity exercise, muscle-strengthening…

A recent study published in JAMA Dermatology explored why dermatologists are still prescribing long-term antibiotics for acne, despite guidelines limiting their use to 3-4 months. The study identified several barriers hindering clinicians’ adherence to guidelines, including a lack of evidence to justify changes in practice, difficulties with iPLEDGE and oral contraceptives, patient demands, and a…

Kerala Public Service Commission is currently accepting applications for the position of Assistant Professor. Interested candidates can apply now. The commission uses cookies for analytics, advertising, and site improvement. By continuing to use the site, users agree to the use of cookies. More information can be found in the Cookie Policy and Cookie Settings. Source…

The American Organization for Nursing Leadership released a report in partnership with Laudio, a startup that provides software for nurse managers, revealing that nearly one-fifth of nurses are projected to leave the healthcare workforce by 2027 due to lack of support from their managers. Nurse managers play a vital role in nurse retention and patient…

Durvalumab, a monoclonal antibody that binds to PD-L1, showed extended overall survival (OS) and progression-free survival (PFS) compared to a placebo for patients with limited-stage small cell lung cancer in a phase 3 ADRIATIC trial. The trial included 730 patients and evaluated durvalumab monotherapy, durvalumab plus tremelimumab-actl, or placebo. The primary endpoints of improved PFS…

Powerful groups of mostly men are making decisions about biology and bodies they know little about, leading to suboptimal medical care for women. Engineers have historically oversimplified designs, leading to issues like the Dalkon Shield and Essure devices causing harm to women. Biomedical design teams lack diversity and knowledge of women’s health, resulting in inadequate…

New Swedish research suggests that extensive lymph node removal may not be necessary for all breast cancer patients. The study tracked outcomes for nearly 2,800 patients with metastases in one or two sentinel nodes. Results showed that post-surgical therapy was effective in controlling cancer spread, even without extensive lymph node removal. Patients with larger metastases…

The research published in The Journal of Nuclear Medicine suggests that PET/MRI can improve diagnostic accuracy for prostate cancer patients and help avoid unnecessary biopsies. The study found that using the PRIMARY scoring system with PET/MRI results could avoid more than 80% of unnecessary biopsies while potentially missing one in eight clinically significant prostate cancer…

Donna Rice, a 65-year-old runner from Arizona, struggled with a hamstring injury for months before seeking help from a physical therapist. Physical therapists offer individualized exercise programs to help improve strength and mobility, especially in older adults. Regular physical therapy can benefit conditions like osteoporosis, osteoarthritis, vertigo, neurological conditions, cancer, and incontinence. The support of…

A study comparing low-dose oral minoxidil and topical minoxidil found that oral minoxidil was just as effective in promoting hair growth as the topical form. The trial was well-designed and included 90 men with androgenetic alopecia. Results showed that oral minoxidil had a higher increase in terminal hair density in the vertex area compared to…

Bayer AG’s subsidiary AskBio has appointed Mansuo Shannon as its new Chief Scientific Officer. Shannon will be responsible for leading the company’s scientific initiatives. Bayer AG’s use of cookies for analytics, advertising, and site improvement is mentioned, with users agreeing to their use by continuing to access the website. More information on the use of…

The MedCity INVEST healthcare startup pitch contest track focused on Consumer/ Employer healthcare highlights women’s health. Scheduled for May 21-22 at the Ritz Carlton in Chicago, the contest will feature six health tech companies. GoNo Food Finder developed an app to scan and recommend foods based on medical conditions. Coologics created a device to treat…

A study presented results from a week 16 analysis of tildrakizumab, an interleukin-23 inhibitor, for the treatment of moderate to severe plaque psoriasis of the scalp. Results showed that a significantly higher proportion of patients treated with tildrakizumab achieved clearance of their scalp psoriasis compared to placebo. Adverse events were reported more in the tildrakizumab…

The article discusses how Western drug makers are seeking alternative suppliers in response to draft U.S. legislation that would restrict working with certain Chinese biotechs. These Chinese companies produce active pharmaceutical ingredients for many U.S. and European drugmakers, prompting companies like Eli Lilly and Vertex Pharmaceuticals to diversify production. In other news, European regulators found…

A study found that treatment with ticagrelor alone, rather than in combination with aspirin, led to a lower rate of clinically relevant bleeding in patients with acute coronary syndrome who underwent percutaneous coronary intervention. The study involved adults who remained event-free for one month on dual antiplatelet therapy after their procedure. Participants were randomly assigned…

A team of researchers led by Huanyu “Larry” Cheng at Penn State developed wearable sensors and a machine learning algorithm to monitor infant movements for early detection of neuromotor diseases. The pilot study showed up to 99.9% accuracy in identifying at-risk infants. This technology is needed to detect issues early, before irreversible damage occurs. The…

Lauren Nicks recalls experiencing adultification bias at a summer camp, where she was scolded for her clothing and perceived as more mature than her age. This bias disproportionately affects Black girls, who are often treated harshly in education and juvenile justice systems. Signs of trauma from this bias can include changes in behavior or academic…

A phase 2 trial investigating a new drug, ninerafaxstat, showed promising results in improving cardiac function in patients with nonobstructive hypertrophic cardiomyopathy (nHCM). While overall cardiovascular outcomes did not show significant improvement, a post hoc analysis revealed that patients with severe symptoms experienced measurable improvements in heart failure symptoms and exercise capacity. This suggests potential…

Lupin has received approval from the CDSCO panel to study a powder for inhalation capsule containing Glycopyrronium Bromide and Vilanterol Trifenatate. This medication is intended for the treatment of respiratory conditions. The company will conduct further research on the product. Cookies are used on the website for analytics and advertising purposes. Continuing to use the…

The traditional fee-for-service healthcare model has been foundational in providing access to healthcare services, but as the industry shifts towards outcomes-based care, specialty practices face unique challenges and opportunities. These practices, including dermatology, ophthalmology, and aesthetics, can lead in healthcare innovation by integrating medical wellness into their services. The focus on wellness aligns with consumer…

The Belfast Health and Social Care Trust is seeking a Consultant in Palliative Medicine, with the opportunity for a joint appointment at the Marie Curie Hospice. The role involves working with community-based colleagues to develop a community service for patients in the Belfast Trust area. The closing date for applications is 16th May 2024 at…

Smith & Nephew has launched its Renasys Edge negative pressure wound therapy system, designed to discreetly treat patients with chronic wounds like ulcers. The system can be carried or worn, allowing patients to go about their daily lives while receiving the prescribed therapy. Smith & Nephew is partnering with SunMed Medical Solutions and First Nation…

Damian bids farewell in the final edition of The Readout at STAT after 8 years of covering biotech. Meghana Keshavan will continue the newsletter. European regulators find no link between new obesity medicines and suicidal thoughts. Moderna halts plans to invest in a Kenya manufacturing site for mRNA vaccines due to insufficient demand. Vertex Pharmaceuticals…

A Botox nasal spray called Haytox is gaining popularity as a treatment for hay fever in Australia and the UK, despite a lack of clinical evidence to support its effectiveness. Claims by private cosmetic clinics hail Haytox as a breakthrough for chronic rhinitis, offering relief for several months without discomfort. However, the treatment has not…

A study published in The Lancet Neurology showed that subcutaneous infusion of ND0612, a levodopa-carbidopa solution, increases on time without troublesome dyskinesia in Parkinson’s disease patients. The study, involving 381 participants, found that compared to oral levodopa-carbidopa, subcutaneous ND0612 provided an additional 1.72 hours of on time without troublesome dyskinesia. Other outcomes, such as daily…

Researchers have developed a microfluidic device to improve the separation of tumor cells and clusters from malignant effusions, aiding in cancer diagnosis and treatment monitoring. This technology enables the high-throughput, continuous-flow separation of single tumor cells, tumor cell clusters, and white blood cells. Understanding tumor clusters’ role in metastasis is crucial, and traditional techniques often…

Maria Davis-Pierre, a licensed mental health therapist, was diagnosed with autism spectrum disorder at age 38 after years of attributing her symptoms to ADHD. She experienced exhaustion, depression, and fatigue common in adults on the spectrum. Many adults with autism spend their lives masking their symptoms, leading to burnout. Seeking a diagnosis in adulthood is…

A recent survey of 204 US oncologists revealed ethical concerns about using artificial intelligence (AI) in cancer treatment decision-making. Most oncologists supported patient consent for AI use and believed they should be able to explain AI-based clinical decision models. However, few felt patients needed to understand AI models. When AI recommended a different treatment than…

Maintaining a healthy lifestyle is important, but often leads to falling into the trap of diet culture, which glorifies thinness and promotes restrictive eating habits. This can result in negative body image, disordered eating patterns, guilt, and shame. To combat these harmful effects, intuitive eating is recommended. Intuitive eating involves listening to your body’s cues,…

AstraZeneca was told by the CDSCO panel to submit an analysis of clinical data specific to the Asian and Indian population regarding their drug Durvalumab. The panel emphasized the importance of understanding how the drug affects these populations to ensure its safety and efficacy. By analyzing this data, AstraZeneca can provide more targeted and personalized…

Novartis is expanding its presence in prostate cancer with the acquisition of the small molecule drug ARV-766 from Arvinas for $150 million upfront, with the potential for up to $1 billion more based on milestones. ARV-766 targets disease-causing proteins for disposal by the cell’s built-in system. The drug has shown promise in targeting androgen receptor…

Dr. Chris Luke discusses his evolving views on politicians, influenced by his childhood experiences and the political figures of his time. He recalls his dislike for Nixon and Thatcher, yet softens towards politicians as he ages. He highlights the modern challenge of social media toxicity towards politicians, urging them to address real issues in healthcare….

IQVIA has expanded its partnership with Salesforce to enhance its customer engagement platform for the life sciences industry. The companies will use IQVIA’s Orchestrated Customer Engagement Platform and Salesforce’s CRM to develop the Salesforce Life Sciences Cloud. IQVIA is licensing its platform to Salesforce for this purpose, with the offering set to be available in…