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Trial using CRISPR to edit HIV out of cells disappoints

BALTIMORE — An ambitious effort to cure HIV with CRISPR genome editing fell short in an early clinical trial, investigators announced Friday morning. In the study, run by Excision BioTherapeutics, researchers tried to use the gene editing tool to address a chief reason HIV has been so hard to cure. While antiviral drugs can clear…

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Arm fat may reveal women and men at risk of spinal fracture

Credit: cottonbro studio from Pexels Measuring the total mass of fat in the arms could potentially predict which women and men over 50 are at risk of spinal fracture, according to research presented at the 26th European Congress of Endocrinology, held 11–14 May, in Stockholm. The findings may help identify high-risk individuals with a more…

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Putting a Hole in Our World

May 10, 2024 – When we’re young, we take our macula for granted. At the center of our retina – the deepest layer of the eye that’s chock-full of photoreceptors and that confers color to our world – the macula is like a high-resolution camera. As light hits our eyes, the retina’s macula recasts our…

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Oral Microbiome Test Could Detect Gastric Cancer Earlier

A mouth rinse used to identify oral microbiome composition could serve as an early-detection tool for gastric cancer, new evidence suggests. Researchers found distinct bacterial composition differences in patient samples that point to the potential for oral microbial signatures to be used as biomarkers for assessing gastric cancer risk.  “Too many patients are being diagnosed…

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This Chip Seeks to Transform Drug Manufacturing by Learning More About Intracellular Dynamics

A new company emerged out of stealth mode this week at the SynBioBeta conference in San Jose. The startup, called CybergenX, is seeking to integrate AI-powered cybergenetic technology into the synthetic biology field. The company, which was born out of the University of Edinburgh, is developing cybergenetic technology to enhance researchers’ understanding of what is…

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The evolving treatment paradigm of Chronic Lymphocytic Leukaemia

Novel targeted therapies are transforming patient outcomes, but further research is required to address unmet clinical needs Paolo Ghia, Professor of Medical Oncology at the Università Vita-Salute San Raffaele in Milan, Italy, outlines the changing treatment landscape of chronic lymphocytic leukaemia (CLL). His work has supported many patients worldwide and he continues to teach, research…

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Rad AI secures $50M for radiology workflow platform and more digital health fundings

GenAI radiology workflow company Rad AI announced it secured $50 million in Series B funding led by Khosla Ventures, bringing the company’s total raise to more than $80 million. WiL (World Innovation Lab) participated in the round, alongside existing investors OCV Partners, Gradient Ventures (Google’s AI-focused fund), Kickstart Fund and ARTIS Ventures.  Rad AI offers…

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Machine learning enables cheaper and safer low-power MRI

Machine learning enables cheaper and safer low-power magnetic resonance imaging (MRI) without sacrificing accuracy, according to a new study. According to the authors, these advances pave the way for affordable, patient-centric, and deep learning-powered ultra-low-field (ULF) MRI scanners, addressing unmet clinical needs in diverse healthcare settings worldwide. Magnetic Resonance Imaging (MRI) has revolutionized healthcare, offering…

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Cows Are Potential Spreaders of Bird Flu to Humans

May 10, 2024 — Cow udders have the same receptors for flu viruses as humans and birds, raising concerns that cows could become “mixing vessels” that help the bird flu virus spread between people. That’s according to new research conducted by scientists at the University of Copenhagen and St. Jude Children’s Research Hospital in Memphis and…

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If at First Tirzepatide Doesn’t Succeed, Keep Trying

NEW ORLEANS — When using tirzepatide (Zepbound, Eli Lilly) to treat obesity, patience may pay off.  New post hoc data from Lilly’s SURMOUNT-1 trial of people with overweight or obesity but not diabetes suggest that the drug will almost always produce at least 5% weight loss eventually, even among slow responders.  “Some obesity treatment guidelines…

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Study: Google reveals new capabilities of Med-Gemini’s LLMs

A study performed by Google Research in collaboration with Google DeepMind reveals the tech giant expanded the capabilities of its AI models for Med-Gemini-2D, Med-Gemini-3D and Med-Gemini Polygenic.  Google said it fine-tuned Med-Gemini capabilities using histopathology, dermatology, 2D and 3D radiology, genomic and ophthalmology data.  The company’s Med-Gemini-2 was trained on conventional medical images encoded…

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New measures to control spread to humans

WASHINGTON — The federal government will provide livestock farms as much as $28,000 apiece to bolster protective measures and testing for the avian flu virus spreading among dairy cows, officials said Friday. The Agriculture Department also allotted $98 million to aid states restricting the interstate movement of affected cattle, and health officials announced they would…

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Study points to personalized treatment opportunities for glioblastoma

Credit: Cancer Cell (2024). DOI: 10.1016/j.ccell.2023.12.015 A study appearing in Cancer Cell uncovers the evolutionary dynamics of glioblastoma recurrence through proteogenomic analysis, offering potential therapeutic avenues. The research team, led by Professor Jason K. Sa from Korea University College of Medicine’s Department of Biomedical Informatics and Professor Jong Bae Park from the National Cancer Center,…

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Teprotumumab Treats Thyroid Eye Disease Across Age

NEW ORLEANS — Teprotumumab (Tepezza) works equally well in both older and younger patients with thyroid eye disease (TED) and regardless of TED duration, new data suggest.  TED is an autoimmune disease characterized by orbital inflammation and expansion of fat and muscles around the eyes, resulting in proptosis, diplopia, pain, redness, and swelling. Many of…

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Review to determine if second ED needed in Mid-West

Emergency facilities in Ennis and Nenagh closed 15 years ago Health authorities will determine if a second emergency department is required in the Mid-West after the Minister for Health announced a review into emergency care capacity in the region. The HIQA assessment will consider the case for a second ED for the region in light…

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Tirzepatide Superior to Placebo in Weight Loss Study

Treatment with tirzepatide was associated with significant weight loss in obese and overweight adults, according to phase 3 data. Tirzepatide is an investigational once-weekly, dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that integrates the actions of both incretins into a single molecule. GIP is believed to complement the effects of GLP-1…

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Rad AI secures $50M for radiology workflow platform and more digital health funding

GenAI radiology workflow company Rad AI announced it secured $50 million in Series B funding led by Khosla Ventures, bringing the company’s total raise to more than $80 million. WiL (World Innovation Lab) participated in the round alongside existing investors OCV Partners, Gradient Ventures (Google’s AI-focused fund), Kickstart Fund and ARTIS Ventures.  Rad AI offers…

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The 5 C’s of media use for children

Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . “ data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later. If you continue to have…

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CBT Tops Mindfulness Therapy for Prolonged Grief Disorder

Cognitive behavioral therapy (CBT) is superior to mindfulness-based cognitive therapy (CT) for reducing symptom severity in patients with prolonged grief disorder, results from a randomized trial showed. While patients receiving grief-focused CBT had a superior response compared with those receiving MT, participants in both groups experienced a significant reduction in symptoms 6 months after treatment….

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Doubting Thomas cannot see the IMT future

Terence Cosgrave is not the Messiah – he’s a very naughty boy My Messiah complex has not been well of late. My experiences of the last month have led me to a place where I can well understand (and sympathise with) the frustration of previous incarnations of (obviously false) ‘Messiahs’. The first complaint would be…

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Fasting in Pregnancy Linked to Lower Birth Weight

HealthDay News — Fasting during pregnancy is associated with lower birth weight; however, dietary composition outside of fasting hours modifies this association, according to the results of a study published online Feb. 15 in PLOS ONE. Fabienne Pradella, PhD, from Johannes Gutenberg-University in Mainz, Germany, and colleagues surveyed 326 Muslim patients who delivered their babies in Mainz….

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Continuous observation of patients at risk of self harm is often ineffective, finds safety report

There is only limited evidence that the current approach to continuous observation of patients at risk of harming themselves when on hospital wards is effective, an investigation has concluded.1 The report from the Health Services Safety Investigations Body (HSSIB) said that sometimes healthcare providers get false reassurance from a patient being on continuous observation, believing…

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Psychological therapy shows promise in improving quality of life for people living with motor neuron disease

Credit: Sơn Bờm from Pexels The largest-ever trial of a psychological intervention for patients with motor neuron disease (MND), conducted by researchers at the University of Sheffield and UCL, found that acceptance and commitment therapy (ACT) improves overall quality of life, when integrated alongside existing care. MND is a progressive, neurodegenerative disease with no cure….

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Custom Video Games Promising for ADHD, Depression, in Kids

Targeted video games could help reduce symptoms of attention-deficit/hyperactivity disorder (ADHD) and depression in children and adolescents, results of a new review and meta-analysis suggested. Although the video game–based or “gamified” digital mental health interventions (DMHIs) were associated with modest improvements in ADHD symptoms and depression, investigators found no significant benefit in the treatment of…

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Why Consumers Leave Their Payer/Provider

Navigation challenges are the top reason consumers stop seeing healthcare providers, while experience issues are the main reason consumers leave their health insurer, a new survey found. The Accenture report, released last week, surveyed more than 9,700 insured consumers and 8,000 consumers who sought or received care in the prior year. The survey is a…

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Mortgage Solutions designed for Medical Consultants

In this article, tailored specifically for Medical Consultants, we delve into the unique financial considerations you face, and the expert solutions provided by Biograph Wealth Advisors Through a real-life case study and comprehensive insights, we explore mortgage options, including incorporating private income, leveraging contract changes like Sláintecare, maximising overpayment benefits, and the advantages of partnering…

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Transcendental Meditation Helps to Alleviate Burnout in Academic Physicians

HealthDay News — Transcendental Meditation is a viable and effective intervention to decrease burnout and depression among academic physicians, according to results of a study published online January 26 in the Journal of Continuing Education in the Health Professions. Marie Loiselle, PhD, from Maharishi International University in Fairfield, Iowa, and colleagues studied the effects of the…

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