Orlynvah, a new drug for urinary tract infections, has been approved by the FDA, providing a new treatment option for patients with limited alternatives. The drug, a combination of sulopenem etzadroxil and probenecid, has shown effectiveness in treating uncomplicated UTIs in adult women. Clinical trials with over 3,800 participants demonstrated that Orlynvah works as well…
Crescent Biopharma is going public through a reverse merger with GlycoMimetics to capitalize on a recent groundbreaking cancer drug development still fresh in investors’ minds. The company’s lead program is a bispecific antibody called CR-001, similar to Summit Therapeutics’ ivonescimab. Crescent aims to replicate the properties of ivonescimab to compete in the checkpoint inhibitor therapy…
Ireland will invest in developing nursing and midwifery professions in Kenya through a new bilateral labour agreement. The plan aims to address shortages in the nursing and midwifery workforce in Ireland by increasing the number of Kenyan nurses and midwives working there. Collaboration with the World Health Organization will help develop and monitor the workforce…
Chronic stress can alter sperm and impact a father’s children’s mental health, increasing their risk for anxiety and depression. This phenomenon is known as epigenetic inheritance, where experiences can leave a mark on genes that are passed down to the next generation. A recent study by researchers at the University of Melbourne focused on how…
Hurricane Helene damaged a Baxter International factory in North Carolina, leading to a shortage of IV fluids across the country. Patients relying on parenteral nutrition, such as those with autoimmune diseases or cancer, are particularly affected as supply issues persist. CVS Health’s subsidiary, Coram, has stopped providing parenteral nutrition, further exacerbating the situation. Some patients…
A high school student presented data at the Lifestyle Medicine Conference showing that implementing a course focused on well-being into the curriculum improved happiness for students. The study compared EPOCH happiness scores in students who took the Science of Well-Being for Teens class to a control group. Students who took the course showed increased happiness…
Get your daily dose of health and medicine through STAT’s free newsletter Morning Rounds, covering topics like Lassa fever and its recent fatality in Iowa, the impact of eviction lawyers on preterm births, and the potential benefits of certain ultra-processed foods. Former President Trump’s comments on vaccines and the role of Robert F. Kennedy Jr….
Annie Sara Mathew, also known as Joyce, was born in a village in Kerala, India. She excelled academically and pursued a bachelor of science before studying medicine in Thiruvananthapuram. There, she met Mathew, also a medical student. Source link
Researchers from the University Hospital Bonn and the University of Bonn have studied how sharp vision is linked to eye movements and cone density in the fovea. Using high-resolution imaging and micro-psychophysics, they found that eye movements are finely tuned to optimize sampling by cones, allowing humans to perceive finer details. The study revealed that…
A Mayo Clinic study found that unipedal balance is a key measure for age-related neuromuscular decline. The study investigated age-related changes in gait, balance, and strength, utilizing a cohort of individuals above 50 years old. Results showed that balance was most affected by aging, with significant declines in strength but no impact on gait. These…
Data from a retrospective study presented at the American College of Gastroenterology 2024 Annual Scientific Meeting suggests that the use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) may decrease the risk of early-onset colorectal cancer (EO-CRC) in patients with type 2 diabetes (T2D). The study analyzed patients under 50 years old with T2D who…
World Stroke Day highlights the importance of awareness and proactive prevention in the fight against stroke, a leading cause of death and disability in the US. While some risk factors like family history and age are beyond our control, lifestyle changes such as a healthy diet, regular exercise, quitting smoking, limiting alcohol intake, and managing…
Tampa General Hospital CEO John Couris is worried about the lack of effective care coordination in the healthcare industry. He believes that the rising healthcare costs and average clinical outcomes in the U.S. are unsustainable. Couris emphasizes the importance of addressing basic issues such as access, care coordination, and patient-provider friction before moving on to…
A study found that consuming 2 oz. of pistachios daily for 12 weeks significantly increased macular pigment optical density and serum lutein concentration in healthy adults. This suggests that pistachios, as the only tree nut with significant lutein content, could be an effective dietary intervention for preserving eye health. The study included 36 participants who…
A charter company working for Charles River Laboratories was fined by Canadian authorities for improperly shipping long-tailed macaques into the country. The flights have prompted an investigation by officials overseeing the endangered species treaty. SkyTaxi was fined $7,500 for lacking permits to transport the primates on three flights from Cambodia. An email exchange revealed that…
Alexander was born in Egypt in 1940 to a Greek mother and English pilot father who died in a bombing raid. He moved to England in 1946 with his mother and grew up in Sussex with his grandparents. He attended Brighton Grammar School as a boarder. Source link
A genetic signature in newborns can predict neonatal sepsis before symptoms appear, according to a new study conducted by researchers at UBC, SFU, and MRC Unit The Gambia. Neonatal sepsis, a severe infection in infants, has higher rates in lower- and middle-income countries, leading to significant morbidity and mortality. The study identified four genes that,…
Researchers at Nationwide Children’s Hospital found in a study published in JAMA Pediatrics that prenatal cannabis exposure can negatively impact children’s cognitive skills and behaviors in early childhood. This includes impulse control, attention, planning ability, and aggressive behavior. The study suggests that using cannabis during pregnancy can have lasting effects on a child’s development and…
The US FDA issued a CRL to PharmaTher for deficiencies in their application for racemic ketamine. The FDA requested new information related to drug substance, drug product, manufacturing, and microbiology. The FDA did not express concern about the stability of the ketamine submission batches. PharmaTher plans to work with their manufacturing partner to resolve the…
Pistachios are a nutrient-dense superfood that supports eye health, heart health, blood pressure, and weight management. Research shows that consuming two ounces of pistachios daily for three months leads to improved macular pigment optical density (MPOD), which is important for visual health. Pistachios are rich in lutein, a plant pigment that is a powerful antioxidant…
AbbVie has acquired Aliada Therapeutics for $1.4 billion to improve drug delivery for Alzheimer’s disease treatments. Aliada’s technology allows antibodies to cross the blood-brain barrier more easily, potentially leading to more effective therapies. The lead program, ALIA-1758, uses a platform technology called Modular Delivery to enhance brain delivery. AbbVie has been investing in Alzheimer’s drug…
The article discusses the disparities in healthcare experienced by Black Americans in rural areas of South Carolina, particularly along the “Corridor of Shame.” Despite efforts to address racial health inequities, policies and decisions at the federal, state, and local levels have perpetuated systemic racism and contributed to preventable deaths and worse health outcomes for Black…
Pregnant women with systemic lupus erythematosus are at a higher risk of adverse outcomes such as miscarriage and preterm delivery if they have either high or low levels of serum vitamin D. A study recommended monitoring maternal vitamin D levels during pregnancy and aiming for a range of 40 ng/mL to 59 ng/mL to reduce…
A new digital avatar therapy has shown promising results in treating auditory verbal hallucinations in people with psychosis, particularly schizophrenia. The therapy involves creating an avatar that resembles the voices in the person’s head and engaging in conversations to confront and gain power over the hallucinations. Results from a Phase 2/3 trial in the UK…
Dr. Ken started his career as a GP in Ipswich and later became a partner in Woodbridge. He moved to various locations before settling in Teignmouth in 1973, where he worked as a single-handed family doctor for the rest of his career. Apart from his clinical work, he was involved in research on hypertension and…
New blood tests for colorectal cancer screening are less invasive than colonoscopies but may not be as effective. A study from Stanford Medicine found that colonoscopies and stool tests are better at detecting early cancers and polyps. The new blood tests are recommended for people who avoid traditional screenings. However, if too many people switch…
A recent study investigated the potential of a new sign, spontaneous headshake after a kinematic event (SHAAKE), to diagnose concussions in athletes. Concussions are mild brain injuries that can have serious consequences if not diagnosed promptly. SHAAKE was observed in nearly 73% of athletes after a collision, with common reasons being disorientation, dizziness, and a…
The AVATAR2 trial, the largest study of avatar therapy to date, shows promising results for reducing auditory hallucinations in patients with psychosis. The therapy allows patients to interact with a computer-generated avatar representing the voice they hear. Results show that patients who received personalized dialogues based on their life history, in addition to treatment as…
Charlotte Lay, a British nurse, met her husband Dave Lay when he saved her from attempting suicide by train in 2019. After reconnecting and dating, Dave was diagnosed with testicular cancer in 2020, thanks to Charlotte’s insistence on seeing a doctor for a bad back. Dave credited Charlotte with saving his life, just as she…
Monte Rosa Therapeutics is developing molecular glue degrader medicines that could be used to treat both cancer and immunological disorders. Novartis has shown interest in a Monte Rosa drug candidate, MRT-6160, designed to target a protein associated with autoimmune disease and has paid $150 million for global rights to the program. The drug is currently…
Cork Kerry Community Healthcare is seeking a General Practitioner for the General Medical Services Scheme in Tralee, Co. Kerry. The position involves providing medical care at the general practitioner level for around 1080 patients under a GMS contract. Doctors participating in the scheme work as contractors rather than employees of the Health Service Executive. Interested…
Diversity plays a significant role in healthcare experiences, with under-represented communities facing challenges in securing top medical jobs. Studies have shown disparities particularly affecting Black residents and under-represented minority women. Intersectionality is a key concept to consider in addressing these inequities. A study published in JAMA in 2024 examined racial and gender disparities in chief…
Belinda Ramones received a call that her brother was in the hospital due to heatstroke while working for the Davey Tree Expert Co. He later died from acute kidney failure caused by heatstroke. This incident highlights the need for national regulations to prevent heat-related illnesses and deaths in the workplace. President Joe Biden has proposed…
In a Healio video exclusive, Dr. Maria Rodriguez discusses how access to contraceptive care affects maternal morbidity and mortality, as well as other reproductive health outcomes. She emphasizes the impact of policy on reproductive health services, particularly through Medicaid. Rodriguez highlights the importance of providing access to a range of FDA-approved contraceptive methods to promote…
The article discusses various updates in the biotech industry. Monte Rosa Therapeutics signed a licensing deal with Novartis for an experimental drug, while AbbVie acquired Aliada Therapeutics for Alzheimer’s disease drugs. David Epstein, former CEO of Seagen, launched a new cancer startup called Ottimo Pharma. A feud between gene-editing companies Prime Medicine and Tessera Therapeutics…
The study conducted by Kawano-Dourado et al. focuses on proactive therapeutic drug monitoring of biologic drugs in adult patients with inflammatory bowel disease, inflammatory arthritis, or psoriasis. The clinical practice guideline aims to optimize treatment outcomes and minimize adverse effects by monitoring drug levels in these patients. The research team consists of senior researchers, clinicians,…
Research from Amsterdam UMC analyzed the data of 3,723 out-of-hospital cardiac arrest patients and found that for the first shock, every minute of delay reduces the chance of survival by 6%. Giving the first shock within six minutes resulted in a 93% chance of stopping the heart rhythm disorder ventricular fibrillation, compared to 75% when…
Evosep, a leader in proteomics solutions, has relocated to new headquarters in Odense to enhance its role in advancing proteomics for pharmaceutical and biotech industries. The new facility will support innovation and high-precision proteomics techniques. Evosep has also launched Evosep Biolabs for high-throughput proteomics and introduced Installation Qualification and Operational Qualification services to ensure regulatory…
Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common liver disease globally, linked to obesity and diabetes. Studies are exploring the use of GLP-1 RAs to treat MASLD by aiding in weight loss and controlling diabetes. GLP-1 RAs have shown promise in resolving MASH and liver fibrosis as well as reducing liver fat content….
A study found that the use of GLP-1 drugs for obesity treatment has led to a 25% decrease in weight loss surgeries. The research analyzed data from over 17 million privately insured adults and showed a significant increase in GLP-1 prescriptions, while weight loss surgeries declined. Only 5% of obese patients received GLP-1 drugs, and…
The NCQA announced updated credentialing standards for 2025, pushing healthcare organizations to meet stricter requirements. The changes reflect a focus on innovation and patient safety, with adjustments to verification turnaround times to align with current industry standards. New guidelines include license monitoring for health plans and capture of social demographic data for providers, aiming to…
Cork Kerry Community Healthcare is seeking a General Practitioner for the General Medical Services Scheme in Mayfield, Co. Cork. The GMS Panel has approximately 548 patients, and the scheme provides medical care at a general practitioner level for medical card patients. Doctors participating in the scheme work under a formal contract for service and are…
Blood volume monitoring-guided hemodialysis was found to decrease hospital stay by 2 days and lead to significantly fewer readmissions for patients with end-stage kidney disease and heart failure. A multicenter cohort study conducted from 2017 to 2020 with 278 hospitalized patients showed that those who received dialysis with blood volume monitoring had a shorter hospital…
The U.S. has the highest maternal mortality rate among high-income countries, with Black women being four times more likely to die than white women. Louisiana ranks low in maternal mortality and lacks mental health services, contributing to pregnancy-associated deaths. Initiatives like the Louisiana Mental Health Perinatal Partnership and the Doula Registry Board aim to address…
Type 2 diabetes affects 1.2 million Australians and is managed through diet, exercise, and medication to control blood glucose levels. A new study suggests that time-restricted eating, focusing on when you eat rather than what you eat, can be as effective as advice from a dietitian in managing blood sugar levels. This approach involves limiting…
Yourgene Health, part of the Novacyt group, has received accreditation for their Yourgene Cystic Fibrosis Base assay under the new EU IVDR requirements. The test is a Class C in vitro medical device intended for use in molecular laboratory environments by healthcare professionals. The accreditation ensures that the test meets stringent quality, safety, and performance…
A study presented at the American Society of Nephrology found that the benefits of the drug empagliflozin in treating chronic kidney disease (CKD) begin to diminish within about a year after treatment is stopped. The EMPA-KIDNEY trial showed that empagliflozin reduced the risk of kidney disease or progression by 28% compared to a placebo over…
Traumatic brain injuries (TBIs) are severe and can have life-altering consequences, ranging from mild concussions to severe impairments. Common causes include car accidents, falls, sports injuries, and workplace incidents. Symptoms vary but can include headaches, dizziness, nausea, memory problems, and mood changes. Treatment depends on the severity, ranging from rest and pain relievers for mild…
During the HLTH conference, key topics discussed included how AI could be deepening health disparities, the challenges retailers face when entering the healthcare space, the economic impact of strict abortion laws, the realization that many investors backed products instead of companies, the importance of healthcare leaders recognizing themselves as being in the customer service industry,…
A study presented at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting found that smokers with asthma were more likely to receive smoking cessation treatment compared to smokers without asthma. The study used an EHR system to identify smokers, with 18.1% of asthmatic smokers and 8.4% of non-asthmatic smokers receiving prescriptions for…