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How to take on Big Pharma and win

In 2013, at age 25, Elizabeth Pfiester founded T1International to address the global insulin price crisis as a type 1 diabetes patient. Over the years, the organization has successfully influenced insulin manufacturers to lower prices and advocated for policy changes. Pfiester emphasizes the need for patients to lead the fight against Big Pharma, rather than…

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Peter Cole: anaesthetist and researcher who highlighted the dangers of passive smoking years before it was considered a public health threat

Peter Cole, an anaesthetist at St Bartholomew’s Hospital in London, was not content with just a conventional hospital consultant role. He was driven by intellectual curiosity and sought to push scientific boundaries. Cole embarked on a long academic career alongside his clinical work, establishing an innovative research laboratory despite limited funding. His research covered various…

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Improvement seen in vaccine completion among military children

A study found that among military children born between 2010 and 2019, there has been improvement in vaccine completion and timeliness, with 74.4% completing the recommended seven-vaccine series. However, children born to younger parents and those with changes in well-child care locations were at higher risk for noncompletion. Completion rates were lowest for certain vaccines….

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Nagi Bioscience launches exclusive Priority Access Program, bringing revolutionary SydLab™ One platform to five leading academic labs for C. elegans research

Nagi Bioscience has launched a Priority Access Program for its SydLab™ One platform, offering exclusive access to five top academic laboratories. The platform revolutionizes C. elegans experimentation by automating processes with microfluidics, robotics, optics, and AI. The participating labs will use SydLab™ One for high-throughput experiments in areas like oncology and neurodegenerative diseases. CEO Matteo…

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Muscle Relaxants for Chronic Pain: Where Is the Evidence?

A systematic review found that long-term use of muscle relaxants can benefit patients with painful spasms, cramps, and neck pain, but not for low back pain, fibromyalgia, or headaches. Certain muscle relaxants like Baclofen, orphenadrine, carisoprodol, and methocarbamol were effective in reducing pain intensity and improving cramp frequency, while others like tizanidine showed benefits for…

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What Will It Take to Improve Healthcare Cybersecurity?

Healthcare leaders are increasing spending on cybersecurity in response to rising cyberattacks, recognizing the need for improved defense posture. During a panel discussion, it was emphasized that building a culture of cybersecurity awareness among all employees is crucial. Basic cybersecurity training for all staff is essential, as well as ensuring that new technologies are developed…

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Consultant appointment activity varies significantly in HSE regions

An analysis of productivity data shows significant differences in the average number of outpatient appointments carried out by hospital consultants in different regions across the country. Consultants in the Dublin and South-East region saw more appointments than those in the Dublin and Midlands region. Nationally, there were fewer outpatient appointments per full-time consultant in 2023…

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Elon Musk’s Neuralink device Blindsight gets FDA breakthrough device designation

Neuralink, Elon Musk’s brain-computer interface implant startup, has received FDA breakthrough device designation for Blindsight, a device that aims to restore vision in blind individuals by implanting a microelectrode array in the visual cortex. The device activates neurons to provide visual images, enabling even the blind from birth to see. This technology is part of…

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Retaining new contact lens wearers is a team effort

At a Vision Expo West panel discussion, optician Jennifer Seymour Brusven emphasized the importance of teamwork among eye care practice staff to support patients starting contact lens wear. Brusven highlighted the significance of providing patients with comprehensive care from the moment they walk in until they leave, stressing that every team member plays a crucial…

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Ginkgo Bioworks makes a bet on AI, hoping for a turnaround

Former investor darling Ginkgo Bioworks is facing layoffs and plummeting share prices, prompting the company to launch new services in artificial intelligence for biological research. The company announced a new AI model and a data service for academic researchers and companies to develop their own models. However, experts are skeptical about Ginkgo’s ability to compete…

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WHO acts to boost access to mpox vaccine

Father of six from Democratic Republic of the Congo receives treatment for mpox at Goma general hospital. Over 16,000 cases of mpox reported in DRC, with 500 deaths. WHO adds MVA-BN mpox vaccine to prequalification list for UN agencies and low income countries. This will help accelerate procurement of the vaccine for communities affected by…

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What Are the Challenges in Building a Consumer-Focused Diagnostic Testing Startup?

The direct-to-consumer medical testing industry is growing, providing patients with a convenient way to address healthcare concerns. However, companies in this space face challenges such as obtaining funding and FDA clearance. Building clinical trials to secure FDA approvals can be costly and time-consuming. Function Health, for example, had to overcome obstacles in dealing with traditional…

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Mater Private Network reaches groundbreaking milestone of over 1,000 procedures in heart treatment

The Mater Private Network in Dublin has achieved a milestone in cardiac care by completing over 1,000 Pulsed Field Ablation procedures for atrial fibrillation patients. The Atrial Fibrillation Institute at Mater Private has become the largest group of EP consultants in Ireland, treating 40% of the country’s AFib patients. Prof Gábor Széplaki, Head of Electrophysiology,…

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Health tech company Fabric acquires TeamHealth VirtualCare

Healthcare technology company Fabric has acquired virtual care provider TeamHealth VirtualCare to expand its care-enablement capabilities. Fabric uses conversational AI to help patients navigate to the appropriate care settings. The merger aims to improve operational efficiency, clinical capacity, and access for health systems and payers. Fabric’s technology will reduce provider work time, lower call center…

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American Health Under Trump — Past, Present, and Future

Recent comments from former President Donald Trump and Republican lawmakers indicate potential health policy pursuits under a second Trump administration, including changes to the Affordable Care Act and repealing Medicare drug price negotiations. Vice President Kamala Harris connected a reported death due to delayed care under a state abortion ban to Trump’s actions on abortion…

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Analyzing the connection between lifelong activity and longevity in aging research

A new research perspective published in Aging on September 9, 2024, explores the relationship between lifelong activity and longevity in aging research. Researchers from the University of California, Davis present a framework for analyzing longitudinal activity and behavior, using advanced statistical methods such as functional principal component analysis. The study focuses on Mediterranean fruit flies…

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Adalimumab Tops Cyclosporine in Preventing Uveitis Relapse

In a study comparing three immunomodulatory agents in patients with severe Behçet disease, adalimumab combined with corticosteroids was more effective in preventing uveitis relapse compared to cyclosporine and interferon alfa-2a. Patients receiving adalimumab had a lower relapse rate and later occurrence of relapse compared to those on cyclosporine or interferon alfa-2a. Adalimumab also had a…

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Medicare Reimbursement for Doctors is in Critical Condition

Independent physicians are facing a financial crisis as the federal government proposes further cuts to Medicare reimbursement rates. While hospitals see reimbursement rates increase, doctor’s offices are experiencing a significant decrease in reimbursement rates over the years. These cuts could lead to layoffs, reduced hours, and other changes that will impact all patients. Physicians are…

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RCSI 2025 scholarship programme offers opportunity for doctors to complete two-year MD research degree

RCSI University of Medicine and Health Sciences offers a two-year StAR MD Degree program for doctors aiming to enhance their clinical careers through research. The program, which has had 92 candidates since 2016, provides structured support and mentorship for research projects. Participants, such as Dr. Conor Toale and Dr. Lisa Prior, have shared positive experiences…

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General Catalyst launches institute to boost global resilience through innovation

Venture capital firm General Catalyst announced the formation of the General Catalyst Institute, focused on helping governments adopt new technologies for global resilience. The organization will work with governments to shape public policy to support startups using emerging technologies and educate on transformative technologies. The organization’s top priorities include partnerships with governments for responsible AI…

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California Medicaid Ballot Measure Is Popular, Well Funded — And Perilous, Opponents Warn

Proponents of Proposition 35 in California are seeking to create a dedicated stream of funding for healthcare for low-income residents. The campaign has raised $48 million and is supported by various stakeholders. However, a small group of community advocates opposes it, citing concerns about potential funding cuts for vulnerable populations. Governor Gavin Newsom has not…

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Medicaid should prepare now to cover twice-yearly PrEP

In June, a clinical trial showed that a twice-yearly injection was as effective as daily oral medication in preventing HIV. The trial was so successful that researchers were instructed to halt the study and offer the injection to all participants immediately. This development is part of a larger push towards longer-acting HIV medications, which reduce…

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Seven days in medicine: 11-17 September 2024

A study published in the New England Journal of Medicine showed that the weight loss injection Saxenda (liraglutide) effectively reduced BMI in children aged 6-11. The trial, funded by Novo Nordisk, found that 46% of children in the liraglutide group experienced at least a 5% reduction in BMI compared to only 9% in the placebo…

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Mixed Results for Adjuvant Pembro in Endometrial Cancer

Phase 3 trial results showed that adding pembrolizumab to adjuvant chemotherapy did not improve disease-free survival in most patients with high-risk endometrial cancer. However, patients with mismatch repair-deficient tumors did benefit significantly from immunotherapy. The study included over 1,000 patients with curative surgery, and those in the dMMR subgroup showed a higher disease-free survival rate…

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4 Things Startups Must Know to Achieve a Successful Tech Pilot

Healthcare providers are increasing their tech and IT spending, conducting tech pilots to improve clinical and operational success. Rosy Wellness, a women’s health startup, shifted to a provider partner model and demonstrated the value of a holistic approach to healthcare management. DexCare, born out of a large health system, emphasizes solid integration plans for tech…

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Amino Health, Motive Practicing Wisely unveil way to bolster ACO performance

Amino Health and Motive Practicing Wisely Solutions collaborated to launch Amino Motivate, an accountable care organization (ACO) optimization solution that provides data-driven physician performance analytics and consulting services. The goal is to help ACOs improve cost, quality, and relevance of care by identifying areas for enhancement and supporting better patient outcomes. The platform integrates health…

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California May Regulate and Restrict Pharmaceutical Brokers

California Governor Gavin Newsom is considering a bill that would regulate pharmacy benefit managers (PBMs), middlemen blamed for high prescription drug costs. The proposed law, spearheaded by Senator Scott Wiener, would require PBMs to pass along 100% of drug rebates to health plans and insurers, among other regulations. Proponents believe this would lower costs for…

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Excess abdominal fat tied to widespread chronic pain

A study published in Regional Anesthesia & Pain Medicine found that excessive abdominal fat is associated with chronic pain in multiple sites, especially in women. Researchers analyzed data from the U.K. Biobank and found that higher levels of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were linked to an increased number of chronic…

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FDA Approves Benralizumab for EGPA Vasculitis Indication

The FDA has approved benralizumab (Fasenra) for the treatment of adults with eosinophilic granulomatosis with polyangiitis (EGPA). This is the second biologic approved for this rare disease, with the first being mepolizumab (Nucala) in 2017. Benralizumab is a monoclonal antibody targeting eosinophils and has shown positive results in a noninferiority trial compared to mepolizumab. It…

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Amino Health, Motive Practicing Wisley unveil way to bolster ACO performance

Amino Health and Motive Practicing Wisely have introduced Amino Motivate, an accountable care organization (ACO) optimization solution that combines data-driven physician performance analytics with consulting services. The goal is to provide ACOs with detailed insights for improving cost, quality, and relevance of care, enabling them to make informed decisions about resource allocation and care strategies….

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Unpacking the FDA’s Non-Recall Recalls

The FDA and medical device manufacturers often allow doctors to continue using equipment that could potentially harm patients despite issuing recalls. This is highlighted in a case of the MitraClip cardiac implant, where although a Class I recall was issued in 2016, doctors were still allowed to use the device with revised instructions. Medical device…

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