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Novel gene-editing therapy continues to show positive results in sickle cell patients

Researchers presented positive findings from the RUBY Trial, focusing on a one-time gene editing cell therapy called renizgamglogene autogedtemcel for sickle cell disease treatment. The treatment was well-tolerated with no serious side effects reported, and patients showed improvements in white blood cells and platelets. The therapy aims to correct the genetic mutation responsible for sickle…

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Tackling challenges in childhood arthritis transition to adult care

Rheumatological diseases, including juvenile idiopathic arthritis (JIA), can affect children, with a need for increased awareness and effective transition from pediatric to adult care. The European Alliance of Associations for Rheumatology (EULAR) included sessions on childhood arthritis at its 2024 congress. Low awareness of childhood arthritis leads to delays in diagnosis and negative outcomes. Initiatives…

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Study Reveals Secret To Healthy Aging

Researchers recommend reducing TV time and dedicating those hours to physical activity to improve healthy aging. Swapping one hour of TV for light physical activity at home can increase the odds of reaching a healthy age of 70 by 8%. Engaging in moderate to vigorous physical activities can boost those odds by 28%. Using TV…

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Citizen’s Assembly ‘stunned’ by slow pace of drugs reform

Paul Reid addressed the inaugural meeting of the Oireachtas Committee on Drugs Use, highlighting the slow pace of change in how society treats individuals with addiction issues. The Citizen’s Assembly on Drugs Use made 36 recommendations, including a new health-based response to drug use, but has seen little progress in their implementation. Reid emphasized the…

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Watch: California Pays Drug Users To Stay Clean

California is implementing a program called “contingency management” to help hard-drug users by paying them to stay clean, focusing on stimulants like meth and cocaine. Participants must regularly provide a clean urine sample to receive payments in the form of gift cards, starting at $10 and increasing with continued abstinence. This initiative has expanded to…

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Novo Nordisk CEO to testify on Ozempic, Wegovy cost

Novo Nordisk CEO Lars Fruergaard Jørgensen will testify before the Senate after Sen. Bernie Sanders threatened to subpoena the company over the pricing of diabetes and obesity drugs. The Senate health committee announced the agreement after a public back-and-forth. Jørgensen’s appearance is a pivot from initially scheduling a vote to subpoena Novo’s U.S. division chief….

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Scientists find a link between increased headaches and hotter temperatures for individuals with migraines

A study from the University of Cincinnati College of Medicine, Icahn School of Medicine at Mount Sinai, and other institutions found a correlation between rising temperatures and increased migraine attacks. The study, presented at the American Headache Society’s annual meeting, looked at the use of Fremanezumab, a drug that blocks a protein responsible for pain…

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New insights into predictors of organ damage in childhood-onset SLE

Childhood-onset systemic lupus erythematosus (cSLE) is a severe autoimmune disorder in children that can lead to early organ damage. The European Alliance of Associations for Rheumatology (EULAR) highlighted the importance of identifying predictors to prevent damage at their 2024 congress. New research presented at the congress focused on factors associated with damage accrual in cSLE,…

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Enhancing QoL in Breast Cancer

Advances in breast cancer detection and treatment have led to an increase in the number of women diagnosed at earlier stages and successfully treated. There are now around four million breast cancer survivors in the United States. Long-term effects of treatment can include fatigue, pain, and mental health issues, while financial toxicity can also be…

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Turning To Junk Food During Stress? Study Says It Increases Anxiety

Researchers have found that consuming a high-fat diet can harm mental health by increasing anxiety. A study found that a high-fat diet disrupts gut bacteria in animals, leading to behavioral changes and influencing brain chemicals, ultimately contributing to increased anxiety. Rats fed a high-fat diet showed increased levels of neuroinflammation and anxiety-like behaviors. The study…

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Length and ‘adversarial’ nature of Medical Council investigations impacting doctors’ mental health – survey

A recent survey found that doctors investigated by the Medical Council experience stress and anxiety, with many reporting negative impacts on their mental health. Some practitioners considered quitting or retired early due to the probe, and a significant number had suicidal thoughts during the investigation process. The primary cause of mental struggles was the length…

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Hot Science: New Material Senses Temperature Without Touch

Researchers at the Chinese Academy of Sciences have developed a material that can sense temperature without direct contact. This material, made of tellurium and copper embedded in polyimide, is thin, flexible, and sensitive to changes in temperature. It can detect infrared waves from a distance, making it suitable for various applications such as robotics, health…

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Done Health CEO and clinical president arrested for alleged $100M scheme

Done Health CEO and clinical president were arrested for allegedly distributing Adderall online, committing healthcare fraud, obstructing justice, and scheming to defraud taxpayers. The company allegedly made over $100 million by prescribing 40 million pills through deceptive social media ads and easy access via telemedicine. They increased revenue by charging monthly subscription fees and structured…

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AMA adopts several new public health policies

The AMA House of Delegates adopted new policies at its annual meeting to promote public health. One policy aims to raise awareness of high-dose biotin supplements interfering with lab tests, including inaccurately low troponin levels. The FDA has warned that high-dosage biotin supplementation may lead to delayed or missed diagnoses of heart attacks. The AMA…

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NIH needs restructuring, key Republican committee chairs say

The article highlights the importance of reforming the National Institutes of Health (NIH) to restore public trust and ensure responsible stewardship of resources. It addresses concerns about transparency, research misconduct, and the need for structural and policy reforms within the agency. The House Energy and Commerce Committee proposes streamlining NIH institutes and centers, addressing issues…

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Revolutionizing Life Science: An Interview with SCIEX

SCIEX attended ASMS 2024, showcasing new innovations and engaging with attendees about future needs. Highlights included fun nighttime activities and the launch of the SCIEX 7500+ system, featuring Mass Guard technology and DJet+ assembly. The system’s speed benefits large quantitation panels and lab productivity. SCIEX also introduced the ZT Scan DIA and AI quantitation software…

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Defining Difficult-to-Treat axSpA and PsA

Experts are working to define “difficult-to-treat” patients with axial spondyloarthritis and psoriatic arthritis who struggle to reach remission despite advanced treatments. Current guidelines lack clear guidance on managing these patients, with various factors contributing to treatment resistance, including noninflammatory causes of pain. Efforts by international groups like ASAS and GRAPPA aim to develop consensus definitions…

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AmeriHealth Caritas Exec: Worst Thing Insurers Can Do Is Be Paralyzed by AI Challenges

At the AHIP 2024 conference in Las Vegas, Neil Gomes, the chief digital officer of AmeriHealth Caritas, emphasized the importance of insurers overcoming challenges in deploying artificial intelligence in healthcare. He highlighted issues such as health literacy, policy building, talent acquisition, and trust in AI. Gomes also warned about the risk of ransomware attacks and…

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Nice guys can be winners too

Dr Michael Mosley, a British television journalist and writer, was known for his ‘gonzo journalism’ style of trying health challenges he discussed. Despite his success, many doctors lack role models for good behavior. Mosley’s impact and influence in public broadcasting, particularly regarding calorie-restricting diets like the 5:2 diet, made him a prominent figure in British…

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California Lawmakers Preserve Aid to Older, Disabled Immigrants

California lawmakers passed a $211 billion budget for 2024-25, rejecting Governor Gavin Newsom’s proposal to cut in-home supportive services for low-income older, blind, and disabled immigrants without legal residency. The budget plan draws more from the state’s rainy-day fund and reduces corporate tax deductions to prevent cuts to health and social services. Advocates applauded the…

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FDA seeks public input on advisory committees

Mitze Klingenberg expressed her devastation during an FDA town hall meeting after an FDA advisory committee voted against an experimental treatment for amyotrophic lateral sclerosis (ALS). She shared that her son, who benefitted from the treatment, was ignored and dismissed as anecdotal by the panel. Klingenberg emphasized the impact of false hope and the need…

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AI can help doctors make better decisions and save lives

A study conducted at The Mount Sinai Hospital showed that using AI-generated alerts based on machine learning algorithms to signal adverse changes in patient health can improve clinical care outcomes. The study found that patients who received real-time alerts were more likely to have their care escalated, leading to improved interventions and lower mortality rates….

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Short-term alcohol abstinence worsens gut health in alcohol use disorder patients

A recent study in PLoS ONE investigated the effects of alcohol consumption and short-term abstinence on gut dysbiosis in individuals with Alcohol Use Disorder (AUD). The study found that abstinent AUD patients had distinct gut microbiota and metabolome compositions, higher mental distress, and no improvement in gut microbial health compared to those still drinking. Patients…

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FDA Expands Repotrectinib Label

The US FDA has approved repotrectinib for solid tumors with NTRK gene fusion that have progressed after initial treatment. The drug is a tyrosine kinase inhibitor initially approved for ROS1-positive lung cancer. NTRK gene fusions are rare but found in many cancer types. Approval is for patients aged 12 and older based on TRIDENT-1 trial…

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Want To Kickstart Your Health Journey? Get Your Cholesterol Checked At Home Today!

Cholesterol-related health complications are a leading cause of death worldwide, with high levels of cholesterol posing a significant risk for heart disease and stroke. Regular cholesterol testing is essential to detect early signs of unhealthy cholesterol levels. At-home cholesterol testing kits offer a convenient and efficient way to monitor cholesterol levels, including important markers like…

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How Healthcare Leaders Are Reacting to the Supreme Court Preserving Abortion Pill Access

The U.S. Supreme Court upheld access to the abortion pill mifepristone, ruling against an anti-abortion physician group’s challenge. The FDA-approved drug, along with misoprostol, is used for abortion up to 10 weeks gestation. The court determined the group lacked legal standing to challenge the FDA’s regulation of the drug. Medical associations praised the decision, emphasizing…

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SCOTUS Rejects Abortion Pill Challenge — For Now 

The Supreme Court rejected a challenge to the abortion pill mifepristone, ruling the group lacked standing. Biden proposed regulations to remove medical debt from credit reports, while Trump tries to take credit for a cap on insulin prices. Drug shortages are increasing, impacting pharmacies and patients. The Southern Baptist Convention restricted in vitro fertilization. Republican…

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Lefthandedness could be an advantage in medicine

Milton’s optimism regarding the advantages of left handedness is supported by the experience of one individual who was trained to be ambidextrous by a right handed mentor. Despite initial difficulties, adaptation came quickly and the long term benefits are evident. This is particularly beneficial in surgical fields, as highlighted by a retired ear, nose, and…

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Exercise in natural settings may provide more benefits than indoor exercise

Regular physical activity offers numerous health benefits, including preventing chronic conditions and improving mental health. Exercising in natural settings like parks is more beneficial than indoors, with studies showing short-term positive outcomes. Factors affecting park usage include physical and natural features, as well as accessibility. However, some demographic groups face barriers to using natural spaces…

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SCOTUS rejects abortion pill challenge — for now

Julie Rovner hosts KFF Health News’ “What the Health?” podcast. The Supreme Court rejected a challenge to the abortion pill mifepristone due to lack of standing, but abortion opponents seek other ways to restrict access. The Biden administration proposes eliminating medical debt from credit reports, while Trump falsely claims credit for Medicare’s $35 insulin cap….

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Significant Benefit With Liver Transplantation in ACLF

Liver transplantation improves survival in patients with acute-on-chronic liver failure (ACLF), with 3-month post-transplantation mortality rates in ACLF grades 2 and 3 similar to those with decompensated cirrhosis. The CHANCE study highlights the inadequacy of current transplant allocation criteria for ACLF patients, leading to excess mortality on the waitlist. MELD scores do not account for…

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